Primary bone tumours in Kashmir valley a retrospective histopathological study

Abstract

The present study was carried out in the postgraduate department of Pathology at Government Medical College, Srinagar, India, to study the histopathological pattern of primary bone tumors in Kashmir valley over a period of 15 years. During this study, 373 histologically proven primary bone tumors were analyzed. Out of these, 298 were benign (79.89%) and 75 were malignant (20.10%). Peak incidence was in the second and third decade of life with male predominance. Among the malignant tumors, the highest incidence was that of Osteosarcoma (52%), followed by Ewing's sarcoma (24%) and Chondrosarcoma (14%). Osteochondroma (49%) was the most frequent tumor in the benign category. The most commonly affected bones were femur, tibia and humerus in that order. Comparison with similar studies from other parts of the globe indicate that the relative frequency of primary bone tumors appears to be low but shows a rising trend in the last 10 years in this part of the world.

Evaluation of neoplastic bone lesions: A morphological study at a tertiary care centre.

“…3 Clinical features of bone tumours are mainly non-specific or not recognised, and usually not detected in the initial stages 11 , so experience in diagnostic orthopaedic pathology is also needed in maintaining the high standard of histological reporting. 12 In present study we evaluate 68 cases of neoplastic lesions of bone, we observed that these lesions are more common in younger persons between 20 -40 years of age, as observed by other studies 13 and the male (60.3%) were found affected more than the females, this was also the observation of other researchers mentioned in the literature. 1,7,10,14 We detect majority of benign (63.2%) cases in our study, which was in consistent with the findings of other studies 10,13,15 some studies showed a very high (84%) frequency of benign tumors 16 , these differences may be due to differences in sample size and selection criteria.…”

“…12 In present study we evaluate 68 cases of neoplastic lesions of bone, we observed that these lesions are more common in younger persons between 20 -40 years of age, as observed by other studies 13 and the male (60.3%) were found affected more than the females, this was also the observation of other researchers mentioned in the literature. 1,7,10,14 We detect majority of benign (63.2%) cases in our study, which was in consistent with the findings of other studies 10,13,15 some studies showed a very high (84%) frequency of benign tumors 16 , these differences may be due to differences in sample size and selection criteria. Among 43 benign tumors, we diagnose majority (25.6%) of cases as osteochondroma followed by 21 % cases of Benign Giant Cell Tumor.…”

Histopathological Evaluation of Neoplastic and Non-Neoplastic Bone Tumours in a Teaching Hospital

“…[7] Benign lesions were more common than malignant lesions. [8][9][10][11][12][13] Neoplastic lesions were found to be more common than non-neoplastic lesions which is in conformity with studies done by Settakom et al [14] Chronic osteomyelitis was most common non-neoplastic condition affecting 7 patients (38.9%). Other non-neoplastic conditions were tubercular osteomyelitis and ABC.…”