PRIMARY INTRACRANIAL CHORIOCARCINOMA ARISING FROM THE PITUITARY FOSSA: Report of an Autopsy Case with Literature Review

Furukawa, Fukumi; Haebara, Hideyuki; Hamashima, Yoshihiro

doi:10.1111/j.1440-1827.1986.tb01065.x

Cited by 5 publications

(5 citation statements)

References 1 publication

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“…3,15,16 Various sites of PICCC have been reported, including the pineal region 3,5,[17][18][19][20][21] and the suprasellar or parasellar region. 5,15,22,23 Less common sites include the lateral ventricle, 2 pituitary fossa, 24 basal ganglia, 2,25 and septum pellucidum. 6 In our study, all tumors were located in the pineal (6/7) and suprasellar (1/7) regions.…”

Section: Discussionmentioning

confidence: 99%

Primary Intracranial Choriocarcinoma: MR Imaging Findings

Qiu²,

Zhang³

et al. 2010

AJNR Am J Neuroradiol

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Section: Discussionmentioning

confidence: 99%

Primary Intracranial Choriocarcinoma: MR Imaging Findings

Qiu²,

Zhang³

et al. 2010

AJNR Am J Neuroradiol

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“…The latter is termed "pure" and is pathologically indistinguishable from gestational choriocarcinoma. Primary choriocarcinomas of the ovary, lung, gastrointestinal tract, heart, and brain are more likely to be nongestational in origin (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15) .…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, guidance must be derived from indirect information. The few reported cases of choriocarcinoma of the ovary (5,19) , lung (7) , and gastrointestinal tract (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15) have been noted to have a poor outcome, with a response being similar to that of germ cell tumors.…”

Section: Discussionmentioning

confidence: 99%

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Primary choriocarcinoma of the vulva

Weiß¹,

Amit²,

Schwartz³

et al. 2001

Int J Gynecol Cancer

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Abstract. Weiss S, Amit A, Schwartz MR, Kaplan AL. Primary choriocarcinoma of the vulva. Primary extrauterine choriocarcinoma is very rare, found mostly in the genital tract (tube, cervix, ovary, vagina). Other sites such as lungs, gastrointestinal tract, heart, brain and submentum also have been reported. A 31‐year‐old woman presented with abnormal uterine bleeding 6 weeks after her last menstrual cycle. Her HCG titer level was 900 mIu/ml. She underwent dilation and curettage (D & C). Pathology failed to reveal any chorionic villi. Further evaluation was done, including a second D & C, laparoscopy, exploratory laparotomy, CT, MRI and ultrasound which all failed to define a source for the elevated HCG titer which subsequently rose to 95,000 mIu/ml 130 days after her last menstrual cycle. At that time a vulvar mass was observed. Fine needle aspiration (FNA) was positive for choriocarcinoma. The patient was treated with one course of methotrexate 60 mg intramuscularly every other day for 5 days. Actinomycin‐D 0.5 mg given intravenously daily for 5 days was added to courses 2–7. Radiotherapy (4000 rads) was applied concomitant with the chemotherapy. The remainder of the mass was subsequently excised. The patient has remained with no evidence of disease for 10 years. This is the first case report of primary vulvar choriocarcinoma.

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“…When outside the genital tract, it is most commonly found in the lung (7) and gastrointestinal tract, including stomach, duodenum, jejunum, colon, esophagus, and pancreas (8)(9)(10)(11)(12)(13) . However, other sites, such as heart (14) , brain (15) , and submentum (16) have been reported. No case of choriocarcinoma of the vulva has previously been reported.…”

mentioning

confidence: 99%

Primary choriocarcinoma of the vulva

Weiss,

Amit,

Schwartz

et al. 2001

International Journal of Gynecological Cancer

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Primary extrauterine choriocarcinoma is very rare, found mostly in the genital tract (tube, cervix, ovary, vagina). Other sites such as lungs, gastrointestinal tract, heart, brain and submentum also have been reported. A 31-year-old woman presented with abnormal uterine bleeding 6 weeks after her last menstrual cycle. Her HCG titer level was 900 mIu/ml. She underwent dilation and curettage (D & C). Pathology failed to reveal any chorionic villi. Further evaluation was done, including a second D & C, laparoscopy, exploratory laparotomy, CT, MRI and ultrasound which all failed to define a source for the elevated HCG titer which subsequently rose to 95,000 mIu/ml 130 days after her last menstrual cycle. At that time a vulvar mass was observed. Fine needle aspiration (FNA) was positive for choriocarcinoma. The patient was treated with one course of methotrexate 60 mg intramuscularly every other day for 5 days. Actinomycin-D 0.5 mg given intravenously daily for 5 days was added to courses 2–7. Radiotherapy (4000 rads) was applied concomitant with the chemotherapy. The remainder of the mass was subsequently excised. The patient has remained with no evidence of disease for 10 years. This is the first case report of primary vulvar choriocarcinoma.

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PRIMARY INTRACRANIAL CHORIOCARCINOMA ARISING FROM THE PITUITARY FOSSA: Report of an Autopsy Case with Literature Review

Cited by 5 publications

References 1 publication

Primary Intracranial Choriocarcinoma: MR Imaging Findings

Primary Intracranial Choriocarcinoma: MR Imaging Findings

Primary choriocarcinoma of the vulva

Primary choriocarcinoma of the vulva

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