Primary jejunal melanoma as a cause of adult intussusception: a case report and review of literature

Olatoke, Samuel; Agodirin, SO; Adenuga, Adedire Timilehin; Lawal, Bashir Oladimeji; Ibrahim, Kazeem O O; Folaranmi, Olaleke Oluwasegun

doi:10.11604/pamj.2019.33.214.18622

Cited by 8 publications

(8 citation statements)

References 8 publications

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“…As in our reported cases, SB metastases are more common with cutaneous as opposed to non-cutaneous melanomas [ 10 ]. Primary mucosal melanomas arising in the SB are rare, remaining a controversial diagnosis as the possibility of a MM from an unidentified or regressed primary cutaneous melanoma should always be considered [ 20 , 21 ].…”

Section: Discussionmentioning

confidence: 99%

The forgotten appearance of metastatic melanoma in the small bowel

et al. 2022

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Background Melanoma is the most aggressive form of skin cancer, with a tendency to metastasise to any organ of the human body. While the most common body organs affected include liver, lungs, brain and soft tissues, spread to the gastrointestinal tract is not uncommon. In the bowel, it can present with a multitude of imaging appearances, more rarely as an aneurysmal dilatation. This appearance is classically associated with lymphoma, but it has more rarely been associated with other forms of malignancy. Case presentation We report a case series of three patients with aneurysmal dilatation in the small bowel (SB) confirmed to be due to metastatic melanoma (MM). All patients had non-specific symptoms; most times being attributed initially to causes other than melanoma. On CT the identified aneurysmal SB dilatations were diagnosed as presumed lymphoma in all cases. In two cases, the aneurysmal dilatation was the first presentation of metastatic disease and in two of the cases more than one site of the gastrointestinal tract was concomitantly involved. All patients underwent surgical resection with histological confirmation of MM. Conclusions Recognition of unusual SB presentation of MM, such as aneurysmal SB dilatation, is important to expedite diagnosis, provide appropriate treatment, and consequently improve quality of life and likely survival of these patients. As the most common cancer to metastasise to the SB and as a known imaging mimicker, MM should remain in any radiologist’s differential diagnosis for SB lesions with aneurysmal dilatation.

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Section: Discussionmentioning

confidence: 99%

The forgotten appearance of metastatic melanoma in the small bowel

et al. 2022

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“…The small bowel is the most common site of intussusception in adults [35]. Adult SBIs have a pathological lead point (such as Meckel diverticulum and adhesions) in up to 90% of cases [3,36]. About 60% of SBI in adults are caused by benign lesions, the remaining ones arise on the basis of a malignant lesion or are classified as idiopathic intussusception.…”

Section: Small Bowel Intussusception (Sbi)mentioning

confidence: 99%

“…In literature, about 50% of malignant lesions causing SBI were metastatic melanomas [3]. Primary melanoma of the small bowel is a rare, but also could be pathological lead point to intussusception [36].…”

Section: Small Bowel Intussusception (Sbi)mentioning

confidence: 99%

Intestinal intussusceptions in children population

Kopystecka

Kopeć

Mitek-Palusińska

et al. 2022

J Educ Health Sport

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Intussusception is an invagination of a proximal segment of the bowel into an immediately adjacent, distal portion of the bowel. Ileocolic intussusception is one of the most common causes of bowel obstruction in children. The peak incidence occurs in infants between five and seven months of age. The etiology of intussusception in children is typically idiopathic, approximately 5-10% of patients have a pathological lead point. Postoperative intussusception is one of the rare causes of intussusception. Children with ileocolic intussusception often present abdominal pain, palpable mass, rectal bleeding, fussiness, and emesis. The most effective imaging method for the diagnosis of intussusception is ultrasound. The treatment of ileocolic and ileoileal intussusceptions is different, the first type requires invasive treatment.

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“…The clinical presentation of small bowel melanomas is often asymptomatic and nonspecific at an early stage of the disease [8]. Although intestinal intussusception is a rare condition in healthy adults, PGM are responsible for 60% of colonic intussusceptions and 30% of small bowel intussusceptions in adult patients [4,8,9]. Hence the low PGM incidence and the uncommon association with small bowel intussusception, the present study reports a case of a 75-year-old male with primary small bowel amelanotic melanoma who presented intestinal intussusception on admission.…”

Section: Introductionmentioning

confidence: 99%

Primary Small Bowel Amelanotic Melanoma and Intestinal Intussusception: A Case Report

Guimbala¹,

Kormann²,

Neto³

et al. 2023

BJCR

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Primary gastrointestinal melanomas (PGM) are usually asymptomatic in the early stages, leading to misdiagnosis. We reported the case of a 75-year-old male patient admitted to our service due to hematochezia, and fatigue. Primary investigation showed small bowel intussusception and surgical treatment was performed. Histopathology and immunohistochemistry analysis identified primary small bowel amelanotic melanoma at an advanced tumor stage. Whereas the patient had a sudden impairment of performance status during hospitalization, no curative oncological approach could be performed. This report highlights the clinical and imaging findings that led to the primary gastrointestinal amelanotic melanoma diagnosis in an elderly patient with intestinal intussusception. The early recognition of prior intussusception signs in adults and elder patients may lead to an earlier oncological diagnosis and a better prognosis.

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Primary jejunal melanoma as a cause of adult intussusception: a case report and review of literature

Cited by 8 publications

References 8 publications

The forgotten appearance of metastatic melanoma in the small bowel

The forgotten appearance of metastatic melanoma in the small bowel

Intestinal intussusceptions in children population

Primary Small Bowel Amelanotic Melanoma and Intestinal Intussusception: A Case Report

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