Primary Solid Tumors of the Heart

Urba, Walter J.; Longo, Dan L.

doi:10.1007/978-1-4612-4898-9_6

Cited by 18 publications

(14 citation statements)

References 65 publications

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“…histologic types: embryonal types, which occur mainly in children and adults, and a pleomorphic variety, which are much less frequent and occur in adulthood (16). There is no specific chamber from which they arise, but they are more likely than any other primary cardiac sarcomas to involve the valves and may manifest with multiple sites of involvement (1). The presentation will depend on the area of involvement, but as with other cardiac sarcomas, congestive heart failure is common.…”

Section: Rhabdomyosarcomamentioning

confidence: 99%

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MR Imaging of Cardiac Tumors

Sparrow

Kurian²,

Jones³

et al. 2005

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Magnetic resonance (MR) imaging is an important tool in the evaluation of cardiac neoplasms. T1-weighted, T2-weighted, and gadolinium-enhanced sequences are used for anatomic definition and tissue characterization, whereas cine gradient-echo imaging is used to assess functional effects. Recent improvements in pulse sequences for cardiac MR imaging have led to superior image quality, with reduced motion artifact and improved signal-to-noise ratio and tissue contrast. Although there is some overlap in the MR imaging appearances of cardiac tumors, particularly of primary malignancies, differences in characteristic locations and features should allow confident differentiation between benign and malignant tumors. Indicators of malignancy at MR imaging are invasive behavior, involvement of the right side of the heart or the pericardium, tissue inhomogeneity, diameter greater than 5 cm, and enhancement after administration of gadolinium contrast material (as a result of higher tissue vascularity). Concomitant pericardial or pleural effusions are rare in benign processes but occur in about 50% of cases of malignant tumors. MR imaging offers improved resolution, a larger field of view, and superior soft-tissue contrast compared with those of echocardiography, suggesting that knowledge of the MR imaging features of cardiac neoplasms is important for accurate diagnosis and management.

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Section: Rhabdomyosarcomamentioning

confidence: 99%

“…The overall frequency of cardiac tumors is quite low, with an estimated cumulative prevalence of 0.002%-0.3% at autopsy and 0.15% in echocardiographic series (1,2). The majority of primary cardiac tumors are benign; of these, myxoma is by far the commonest, with lipomas and fibromas occurring less frequently.…”

Section: Introductionmentioning

confidence: 99%

MR Imaging of Cardiac Tumors

Sparrow

Kurian²,

Jones³

et al. 2005

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307

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“…Primary cardiac tumors are very rare with an autopsy incidence of 0.17–0.28% 14 whereas those metastatic to the heart occur with 10–20 fold higher incidence, 6 making cardiac tumors in general a rare but serious condition. Once a cardiac tumor is visualized it becomes paramount to obtain tissue biopsy for diagnosis in order to guide further investigation and therapy.…”

Section: Mass Biopsymentioning

confidence: 99%

Transthoracic Echocardiography Guided Procedures in the Catheterization Laboratory

et al. 2007

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“…Extension of the tumor into the subepicardial fat and pericardial cavity may also occur. Kaposi's sarcoma preferentially involves the subepicardial fat [47,48].…”

Section: Selected Primary Malignant Cardiac Tumorsmentioning

confidence: 99%

Primary malignant cardiac tumors: Update 1992

Thomas

Johnson

Stoddard

et al. 1992

Med. Pediatr. Oncol.

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CLINICAL SUMMARYA 37-year-old male initially complained of polyarthralgias, fever and shortness of breath in February of 1986. Physical examination was unremarkable and routine laboratory analysis was unrevealing. The ANA and rheumatoid factor were negative. The sedimentation rate was 62 (elevated), and the C-reactive protein was 7.2 (elevated). The patient was initially thought to have adult onset Still's disease or familial Mediterranean fever. He was started on aspirin and later switched to oral steroids with marginal resolution of symptoms.With the persistence of symptoms, the patient was admitted to a hospital in April. The arthralgias and dyspnea worsened. Past medical and surgical histories were unremarkable. The family, social, and work history were all noncontributory. Physical examination was remarkable for a temperature of 99.6"F, hyperdynamic precordium, with the first heart sound maximally heard at the apex and the second heart sound maximally heard at the base. There was a 3/6 crescendo murmur heard at the apex which radiated toward the axilla, compatible with mitral valve regurgitation. Approximately 0.12 seconds after the second heart sound, a plop, followed by a soft diastolic rumble, was audible. Musculoskeletal exam failed to reveal clubbing, cyanosis, edema or joint swelling. Chest radiographs were remarkable for bilateral small pleural effusions as well as bilateral interstitial infiltrates at the bases. Computed tomography of the chest revealed an interstitial pattern in the lungs. A gallium scan noted diffuse bilateral lung parenchymal uptake.A 2-D echocardiogram revealed a 3.0 X 3.0 cm distal left atrial mass which was attached to the posterior atrial wall above the posterior mitral leaflet. It appeared to prolapse into the valve orifice during diastole.It was felt that the patient had an atrial myxoma, and a thoracotomy was undertaken on April 15, 1986. The atrial mass was identified and resected. The lesion had a pedunculated stalk arising approximately 4.0 mm above the posterior leaflet of the mitral valve annulus. The 0 1992 Wiley-Liss, Inc.

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Primary Solid Tumors of the Heart

Cited by 18 publications

References 65 publications

MR Imaging of Cardiac Tumors

MR Imaging of Cardiac Tumors

Transthoracic Echocardiography Guided Procedures in the Catheterization Laboratory

Primary malignant cardiac tumors: Update 1992

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