Principais causas de internações em uma unidade neonatal no extremo Norte do Brasil / Main causes of hospitalizations in a neonatal unit in the extreme North of Brazil

Silva, Andressa Gomes da; Cardoso, Andréa dos Santos; Oliveira, Cleonice Barbosa de; Moura, Hadassa Oliveira de

doi:10.34119/bjhrv3n5-086

Cited by 5 publications

(6 citation statements)

References 2 publications

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“… 18 Another study showed that prematurity was responsible for 48% of the admissions, while respiratory dysfunction was responsible for 18.9%. 23 This article, based on secondary data collection, considered only the diagnosis that led to admission of the newborn to the NICU. One of its limitations, therefore, is the fact that it cannot include relevant pathologies that may have emerged during continued care or coexisted with the main pathology — with delayed diagnosis — since they may have influenced the definition of treatment.…”

Section: Discussionmentioning

confidence: 99%

Prescription of off-label and unlicensed medication for newborns hospitalized in the Intensive Care Unit

Santos,

Iser

et al. 2024

Rev. paul. pediatr.

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Objective: To analyze the prevalence of off-label and unlicensed prescriptions for a population of neonates admitted to the Neonatal Intensive Care Unit in a hospital in southern Santa Catarina. Methods: Observational study with a cross-sectional design. All neonates admitted to the Intensive Care Unit during the period from March 2020 to March 2021 were included. Data collection was performed through a questionnaire made by the authors and the classification of drugs based on the Electronic Drug Description (Bulário Eletrônico) of the Brazilian Health Regulatory Agency and Drug Dex-Micromedex. Results: Data from 296 neonates were evaluated. The prevalence was 50,7% for prescribing off-label medications and 37,2% for unlicensed medications. The use of drugs was higher in preterm neonates, with low birth weight, 1st minute Apgar between 6–8, 5th minute Apgar between 7–8, and in need of invasive procedures. The most used off-label drugs were ampicillin, gentamicin and fentanyl (92.6, 92.0 and 26.6%, respectively), whereas the most used unlicensed drugs were caffeine, phenobarbital and bromopride (78.1, 16.3 and 10.9%, respectively). Conclusions: This study showed a large percentage of prescriptions made in the off-label (50.7%) and unlicensed (37.2%) form in the Neonatal Intensive Care Unit, corroborating the worrying world scenario. The most exposed neonates were precisely the most vulnerable ones and, among the most commonly prescribed medications, ampicillin and gentamicin stood out in off-label form and caffeine in unlicensed form.

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Section: Discussionmentioning

confidence: 99%

Prescription of off-label and unlicensed medication for newborns hospitalized in the Intensive Care Unit

Santos,

Iser

et al. 2024

Rev. paul. pediatr.

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“…For Silva et al 2020, respiratory disorders are among the main causes of admission to a neonatal ICU, and there are several possible causes, ranging from prematurity and surfactant deficiency to the clinical repercussions of a systemic disease.…”

Section: Discussionmentioning

confidence: 99%

Gestational and Neonatal Outcomes After Coronavirus Infection: A Systematic Review

Santos¹,

Moreira²,

Silva³

et al. 2022

JHS

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Introduction: Covid-19 is a disease caused by the SARSCOV-2 virus. The first cases emerged in December 2019 in China and evolved into a global pandemic since 2020. In those infected, the clinical picture of the disease can range from mild or asymptomatic symptoms to severe forms with complications. It was found that during pregnancy there is a greater risk of maternal complications, especially when it occurs in the last trimester of pregnancy and puerperium, with an increase in cases of maternal death. Goal: To review the most prevalent possible gestational and neonatal complications in those infected with SARS-COV-2. Methodology: This is a systematic literature review with articles published in PubMed/MEDLINE, Scientific Electronic Library Online (SciElo), Latin American and Caribbean Health Sciences (Lilacs) databases published in the period between February 2020 and December 2021, with the descriptors: "pregnant women", "neonates" and "SARS-CoV-2, with their translations into English, joined through the Boolean operator "AND" in the advanced search. Original publications were chosen. Results/Discussion: data were obtained from 2243 patients, all pregnant and with a confirmed diagnosis of SARSCoV-2. The most reported symptoms were: fever, cough, dyspnea and sore throat. A high prevalence of cesarean deliveries was found. Preterm birth was the most common obstetric complication, followed by PRMO. Significant percentages of neonates evolved with some type of respiratory disorder and died. Conclusion: the most prevalent clinical manifestations in pregnant women with COVID-19 were similar to those found in pregnant women without the infection; high percentages of obstetric and neonatal complications and cesarean deliveries have been described after COVID-19 infection.

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“…Correa (2019) 9 apresentou 56,7% de prematuros em sua pesquisa. Silva (2020) 14 , estudo realizado no Norte do Brasil, apresentou 48%. Nascimento (2020) 15 descobriu a prematuridade em 69,7% dos internados em terapia intensiva neonatal em um hospital do estado de Alagoas, no Nordeste do Brasil.…”

Section: Introductionunclassified

“…Nascimento (2020) 15 descobriu a prematuridade em 69,7% dos internados em terapia intensiva neonatal em um hospital do estado de Alagoas, no Nordeste do Brasil. Assim, acredita-se que a representação dos prematuros pode variar de acordo com o acesso da população ao pré-natal, à assistência obstétrica e a fatores socioeconômicos 9,14,15 A predominância de prematuros nesta pesquisa pode ser justificada pela grande participação de cesáreas, em que foram encontrados valores de 69,5% entre os partos, associado também à grande representatividade do desconforto respiratório, que tem relação com recém-nascidos prematuros já comprovada no literatura médica. Além disso, cabe questionar se os elevados números de prematuridade nesta unidade de terapia intensiva estariam associados ao período de internação, que foram estudados durante a pandemia da COVID-19.…”

Section: Introductionunclassified

Fatores Preditores Para Admissão De Neonatos Em Unidade De Terapia Intensiva Em Um Hospital No Sul De Santa Catarina

Esmeraldino Mendes Filho,

Dal-Bó Michels,

Silveira Boeger

2024

Braz. J. Implantol. Health Sci.

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Introdução: O Brasil inscreveu prepronderante redução da taxa de mortalidade neonatal entre os períodos de 1990 e 2019. Contudo, ainda permanece com valores três vezes maiores que países como Canadá e Estados Unidos. Neste sentido, a terapia intensiva age como principal ferramenta de suporte para estes pacientes que viriam a óbito, tornando-se importante o conhecimento sobre quais motivos levam o recém-nascido a ser admitido em terapia intensiva, para que seja possível traçar metas que reduzam a elevada mortalidade neonatal ainda persistente no país. Objetivo: Analisar fatores preditores de mortalidade e admissão de recém-nascidos em uma unidade de terapia intensiva neonatal. Métodos: Estudo observacional do tipo coorte retrospectiva desenvolvido através da análise de prontuários de neonatos internados em terapia intensiva em um hospital no Sul do Brasil, e suas respectivas progenitoras, no período de 01 de janeiro de 2020 a 31 de junho de 2022. Resultados: Foram avaliados dados de 259 neonatos e suas progenitoras. Desconforto respiratório esteve presente em 79,2% dos neonatos, prematuridade em 69,9% e baixo peso em 57,5%. Usuários de ventilação positiva tiveram 80,4% menos risco de morte. O óbito foi encontrado em 6,9%. Conclusão: Desconforto respiratório, prematuridade e baixo peso foram os principais diagnósticos preditores de admissão. Prematuros extremos, baixo peso, doenças congênitas, submetidos à intubação orotraqueal, cirurgia, manobras de reanimação e uso de fármacos vasoativos foram associadas ao óbito. Questiona-se uma possível associação entre elevados valores de prematuridade e o intervalo de análise dos pacientes, realizado durante a pandemia de COVID-19.

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Principais causas de internações em uma unidade neonatal no extremo Norte do Brasil / Main causes of hospitalizations in a neonatal unit in the extreme North of Brazil

Abstract: Principais causas de internações em uma unidade neonatal no extremo Norte do Brasil Main causes of hospitalizations in a neonatal unit in the extreme North of Brazil

Cited by 5 publications

References 2 publications

Prescription of off-label and unlicensed medication for newborns hospitalized in the Intensive Care Unit

Prescription of off-label and unlicensed medication for newborns hospitalized in the Intensive Care Unit

Gestational and Neonatal Outcomes After Coronavirus Infection: A Systematic Review

Fatores Preditores Para Admissão De Neonatos Em Unidade De Terapia Intensiva Em Um Hospital No Sul De Santa Catarina

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