Principles of surface-enhanced Raman spectroscopy

White wine phenolics: current methods of analysis

“…Raman spectroscopy was used to analyse white wine phenolic acids and sugar components 143,144 . This research was proposed to fill a gap in the literature as only one paper 142 had so far been published documenting the use of Raman spectroscopy for white wine analysis, where the ethanol content of the wine was determined.…”

“…It should be noted that surface‐enhanced Raman spectroscopy (SERS) can be employed to improve the signals obtained from samples for low‐concentration applications. The signal is increased through electric field enhancement with the aid of a noble metal substrate 143 …”

Enabling spectral barcoding of SERS nanotags using gold nanostars

“…The SERS enhancement factor of AuNSs was calculated by comparing the intensities of AuNS@TFMBA and the reference sample (1 M of TFMBA solution in ethanol) (presented in Fig. S5 †) using the following equation: 12,41 Table 1 Band assignments to the distinct Raman vibrations of the seven SERS nanotags 33,35,[47][48][49][50][51][52][53] Raman reporter molecule In this calculation, we assume that the surface of nanoparticles are fully covered by a monolayer of Raman reporter molecules. This assumption is valid for TFMBA since it binds to the surface of AuNSs through Au-S binding.…”

“…9 It has been reported that the magnitude of SERS is proportional to the fourth power of the enhanced electric field, up to 10 7 -10 8 -fold enhancement in the Raman signal, which can be obtained by the electromagnetic enhancement mechanism. 9,12 Therefore, designing metal nanostructures with a stronger enhanced electric field is desirable for designing SERS nanotags. SERS nanotags are unique labels that could be used for multiple and simultaneous detection of different biomolecules.…”

A review of cardiac troponin I detection by surface enhanced Raman spectroscopy: Under the spotlight of point-of-care testing

“…By the interaction of the detection probes with the AAC, the sandwich-shape immunocomplexes (S-SIC) are formed ( Smolsky et al, 2017 ). Although antibodies are the generic biomarker-capture reagents used in the ELISA immunoassay method, they can be substituted by aptamers, a more efficient oligonucleotide-based reagent ( Thiviyanathan and Gorenstein, 2012 ; Kimoto et al, 2019 ; Bognár and Gyurcsányi, 2020 ; Wang X. et al, 2021 ; Majdinasab et al, 2022 ). Once the immunoassay is completed, the Raman experiments can be performed either directly in the solution where the S-SIC were formed or in a dry way on the capture substrate where the immunoassay was driven (see Figures 4A,B ).…”