Production of gluconic acid from glucose by Aspergillus niger: growth and non-growth conditions

Znad, Hussein; Markoš, Jozef; Báleš, V.

doi:10.1016/s0032-9592(03)00270-x

Cited by 78 publications

(40 citation statements)

References 4 publications

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“…Another possible alternative is oxidation catalyzed by enzymes. Microbial fermentation of carbohydrates is cheap and well known but suffers from many disadvantages [6]. Hence, highly selective enzymes are isolated from living cells and used as a catalyst.…”

Section: Current Trends In Carbohydrate Oxidationmentioning

confidence: 99%

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From a Review of Noble Metal versus Enzyme Catalysts for Glucose Oxidation Under Conventional Conditions Towards a Process Design Analysis for Continuous-flow Operation

Dencic¹,

Meuldijk²,

Croon³

et al. 2011

J Flow Chem

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A methodology for the ex ante evaluation of different processing options is proposed. Current processes for glucose oxidation and possible improvements using microreactor technology are investigated. As twofold prime research objectives, the oxidation with noble metal catalyst versus enzymatic oxidation and the oxidation under conventional process conditions versus under Novel Process Windows are explored. Operation and design of an active and stable catalyst, reactor performance, and work-up are included. This ex ante analysis gives information of the critical aspects of a process prior to technology development and facilitates the development of new process routes; especially valuable if step and paradigm changing routes are undertaken, with even no vague idea on their performance potential and with high technological risk. The methodology used for gluconic acid production will be transferred to other chemicals which have the potential in using microreactor technology and Novel Process Windows.

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Section: Current Trends In Carbohydrate Oxidationmentioning

confidence: 99%

“…Liquid side mass transfer coefficient can be calculated from the values of Sh and Gz number, (6) Calculating the value for a micrometer size catalyst particle and parameters given above, it follows that F ~ 10 −3 what is smaller than 1, therefore, internal diffusion is not significant.…”

Section: Reactor Designmentioning

confidence: 99%

From a Review of Noble Metal versus Enzyme Catalysts for Glucose Oxidation Under Conventional Conditions Towards a Process Design Analysis for Continuous-flow Operation

Dencic¹,

Meuldijk²,

Croon³

et al. 2011

J Flow Chem

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“…The glucono-delta-lactone is a food item with valuable features like even pH development and impartial taste forming a favoured additive for diverse foods like bread, mozzarella, sea food, meat, tofu etc. (Znad et al, 2003). Also, it is transformed to gluconic acid by fermentation method or through electrophoresis (Ramachandran and Fontanille, 2006).…”

Section: Introductionmentioning

confidence: 99%

Application of glucose oxidase for the production of metal gluconates by fermentation

Khurshid¹,

Kafiat²,

Hanif³

et al. 2013

Afr. J. Biotechnol.

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The present study deals with the application of glucose oxidase (GOX) for the production of metal gluconates by fermentation method. It provides a method for the conversion of glucose into gluconic acid and its derivatives using the enzyme glucose oxidase (GOX). Due to the presence of calcium carbonate in fermentation medium the gluconic acid is converted into calcium gluconate. Conditions like concentration of substrate, temperature, pH, fermentation period and different phosphate sources were optimized during fermentation. The maximum GOX activity was observed at 35°C (pH 5.5) after 44 h of incubation at 100 rpm. At the maximum enzyme activity, the percentage yield of gluconates are also maximum; both go side by side. Sulphuric and oxalic acids method were employed for the production of gluconic acid. Derivatives of gluconic acid that is, calcium lactate gluconate, sodium gluconate, potassium gluconate, zinc gluconate and copper gluconate were formed by using double displacement and direct methods. The direct method gave the better yield. The percentage yields were 73, 89.63, 81.93, 92.86 and 81.53%, respectively.

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“…Due to these physiological and chemical properties, GA itself and its salts have found extensive demand in construction, chemicals, pharmaceuticals, food, beverage, textile, leather and other industries [1][2][3]. There are various approaches available for the production of gluconic acid namely, chemical, electrochemical, biochemical, bioelectrochemical, and photocatalytic approach [4][5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Gluconic Acid Production from Golden Syrup by Aspergillus niger Strain using Semiautomatic Stirred-Tank Fermenter

Purane¹

2012

J Microb Biochem Technol

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The gluconic acid batch fermentation was conducted using mutant Aspergillus niger NCIM 530 strain under submerged condition in 50 L semiautomatic stirred-tank fermenter. Certain cost-effective source as golden syrup was effectively utilized instead of glucose for successful industrial fermentation process. The significant level of gluconic acid (85.2 gL -1 ) production was observed with maximum 86.97% glucose conversion over 44 hours. This process provides great advantages over traditional submerged fermentation strategies and substrates, as showed by effective production of gluconic acid by utilizing novel substrate as a golden syrup. To reduce analysis time with better accuracy, an effort has been made to use a method for evaluation of parameters like conversion of substrate and production of gluconic acid during the fermentation by using High Performance Thin Layer Chromatography (HPTLC).

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Production of gluconic acid from glucose by Aspergillus niger: growth and non-growth conditions

Cited by 78 publications

References 4 publications

From a Review of Noble Metal versus Enzyme Catalysts for Glucose Oxidation Under Conventional Conditions Towards a Process Design Analysis for Continuous-flow Operation

From a Review of Noble Metal versus Enzyme Catalysts for Glucose Oxidation Under Conventional Conditions Towards a Process Design Analysis for Continuous-flow Operation

Application of glucose oxidase for the production of metal gluconates by fermentation

Gluconic Acid Production from Golden Syrup by Aspergillus niger Strain using Semiautomatic Stirred-Tank Fermenter

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