Profil Fraksi Sitotoksik terhadap Sel Murine Leukemia P-388 dari Ekstrak Biji Honje (Etlingera elatior)

Rusanti, Alfindah; Sukandar, Dede; Rudiana, Tarso; Adawiah, Adawiah

doi:10.15408/jkv.v0i0.3640

Cited by 5 publications

(5 citation statements)

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“…Almost all parts contain monoterpenes, terpenoids, sesquiterpenes, saponins, steroids, flavonoids, triterpenoids, alkaloids, and tannins. The plant extract can be used as an anticancer agent, especially an antileukemic agent (Rusanti et al, 2017), antioxidant (Maimulyanti and Prihadi, 2015), insect repellents and termiticides (Rislyana et al, 2015), antibacterial and antifungal agents to inhibit Salmonella thypi, Shigella sp., Aspergillus flavus, Streptococcus mutans, and in fish spoilage (Angin, 2015;Suryani et al, 2019;Nasution et al, 2020;…”

Section: Etlingera Elatiormentioning

confidence: 99%

Etlingera (Zingiberaceae) in Bogor Botanic Gardens: Potential Benefits and Its Conservation Status

Novitasari

2023

JRBA

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Indonesia is one of mega biodiverse countries in the world, with a high global biodiversity index and many vascular plant species. However, not all plant species are known in terms of their uses, potential benefits, and conservation status. One of example is genus Etlingera, where further studies are required. Therefore, this study aimed to provide information on the potential benefits and uses of the genus Etlingera and to investigate its conservation status. The study was conducted using the method of literature study, an inventory of potential uses, and an inventory of the genus Etlingera living in Bogor Botanic Gardens through direct observation. Six species of the genus Etlingera were collected from the Bogor Botanic Gardens, namely Etlingera brevilabrum, E. elatior, E. hemisphaerica, E. loerzingii, E. megalocheilos, and E. walang, conservation status of three species (E. brevilabrum, E. hemisphaerica, and E. megalocheilos) is Least Concern (LC), two species (E. elatior and E. walang) are Data Deficient (DD), and one species (E. loerzingii) is Vulnerable (VU). All species are commonly used as spices, condiments, cosmetics, and traditional medicine to cure various diseases, possibly also as ornamental plants. The secondary metabolites present in some species, namely E. brevilabrum, E. elatior, and E. hemisphaerica can be used as antimicrobial, antifungal, and antioxidant agents.

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Section: Etlingera Elatiormentioning

confidence: 99%

Etlingera (Zingiberaceae) in Bogor Botanic Gardens: Potential Benefits and Its Conservation Status

Novitasari

2023

JRBA

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“…11,12,13 Kandungan senyawa pada bunga kecombrang yang berhasil diidentifikasi antara lain flavonoid, saponin, tanin, alkaloid, fenol, terpenoid, polifenol, steroid, dan minyak atsiri. 14,15 Aktivitas antibakteri ekstrak etanol bunga kecombrang sudah banyak dilaporkan. Konsentrasi hambat minimum ekstrak etanol bunga kecombrang terhadap bakteri Staphylococcus aureus, Bacillus cereus, Listeria monocytogenes, Pseudomonas aeruginosa, Escherichia coli, Propionibacterium acnes, dan Aeromonas hydrophila secara berurutan yaitu 13 mg/mL, 6 mg/mL, 4 mg/mL, 3 mg/mL, 4 mg/mL, 20%, dan 3 mg/mL.…”

Section: Pendahuluanunclassified

“…Hal ini sesuai dengan penelitian sebelumnya yang menunjukkan bahwa kandungan senyawa pada bunga kecombrang antara lain flavonoid, saponin, tanin, alkaloid, fenol, terpenoid, triterpenoid, polifenol, steroid, dan minyak atsiri. 15,18 Uji degradasi biofilm P. gingivalis dengan ekstrak etanol bunga kecombrang dilakukan menggunakan metode microtiter plate assay yang merupakan gold standard untuk menguji biofilm. Metode ini memiliki luaran berupa nilai optical density (OD) yang menunjukkan kepadatan biofilm P. gingivalis.…”

Section: Pembahasanunclassified

The Activities of Torch Ginger Flower (Etlingera elatior) Ethanol Extract on Degradation of Porphyromonas gingivalis Biofilm as Periodontal Pathogen

Putri,

Widodo,

Ichsyani

et al. 2023

J Indones Dent Assoc

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Introduction: Porphyromonas gingivalis is bacteria that can form biofilms as the main cause of periodontitis. Mouthwash therapy in long term can cause mucositis and even oral cancer. Antibacterial potential of torch ginger flower (Etlingera elatior) can be developed as an alternative adjuvant therapy for periodontitis. Objective: Aims of this research was to determine the effect of torch ginger flower ethanol extract against degradation of P. gingivalis biofilm. Methods: This research used ethanolic extract of torch ginger flower with concentrations 1.56 mg/mL, 3.125 mg/mL, 6.25 mg/mL, 12.5 mg/mL, 25 mg/mL, and 50 mg/mL. Chlorhexidine gluconate 0.2% was used as positive control and DMSO 1% was used as negative control. Measurement of P. gingivalis biofilm degradation used microtiter plate assay with crystal violet 1% staining which reads its optical density at wavelength of 450 nm. Data were analyzed by one way ANOVA and Post hoc LSD. Results: The percentage of P. gingivalis biofilm degradation with torch ginger flower ethanol extract sequentially were 12.47%, 30.56%, 57.12%, 71.36%, and 74.83%. The analysis showed that there was a significant difference (p<0,05) between treatment groups torch ginger flower ethanol extract, as well as between torch ginger flower ethanol extract with DMSO 1% and chlorhexidine gluconate 0.2%. Optimum concentration of ethanol extract of torch ginger flower on P. gingivalis biofilm degradation was 25 mg/mL and showed no significant difference with chlorhexidine gluconate 0,2% (p>0,05). Conclusion: Conclusion of this research is torch ginger flower (Etlingera elatior) ethanol extract has P. gingivalis biofilm degradation activity.biofilm

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“…Kegunaan kecombrang yang lain adalah mengobati sakit telinga serta penghilang bau badan. Bahkan beberapa penelitian menunjukkan efek kecombrang sebagai antioksidan, repellent pengusir nyamuk, larvasida, anti radang, serta anti kanker (Farida & Maruzy, 2016;Resna et al, 2021;Rusanti et al, 2017;Saudah, Zumaidar, Darusman, Fitmawati, Roslim, & Ernilasari, 2022). Kandungan antioksidan pada batang kecombrang juga berfungsi untuk meningkatkan sistem imun (Bogoriani et al, 2022).…”

Section: Pendahuluanunclassified

Potensi Antioksidan Batang Kecombrang (Bongkot) Bagi Kesehatan

Yuliana

2023

Biopros

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Sambel bongkot adalah pelengkap masakan tradisional Bali yang sangat digemari di kalangan masyarakat setempat. Bongkot disebut juga kecombrang di daerah Jawa. Sambel bongkot dibuat dari batang bongkot (kecombrang) yang muda dan diberikan bumbu sambal mentah. Namun, banyak yang belum mengetahui manfaat bongkot bagi kesehatan karena potensi antioksidannya. Tujuan tulisan ini adalah mengetahui potensi antioksidan batang kecombrang (bongkot) bagi kesehatan. Metode: Tulisan ini merupakan narrative literature review. Jurnal diambil dari Google Scholar, Science Direct, dan PubMed. Publikasi jurnal dicari terbitan dalam 10 tahun terakhir (2013-2023). Kecombrang sebagai tanaman unik memiliki banyak manfaat, mulai dari daun, buah, bunga, dan batang (rimpang). Batang kecombrang memiliki kadar antioksidan yang cukup tinggi. Antioksidan yang ditemukan adalah asam askorbat, tannin, flavonoid, terpenoid, dan polifenol. Antioksidan berperan penting untuk memerangi radikal bebas dan dapat menginhibisi sel tumor. Simpulan: potensi antioksidan batang kecombrang (bongkot) bagi kesehatan menunjukkan kandungan asam askorbat, tannin, flavonoid, terpenoid, dan polifenol yang dapat memerangi radikal bebas dalam tubuh.

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Profil Fraksi Sitotoksik terhadap Sel Murine Leukemia P-388 dari Ekstrak Biji Honje (Etlingera elatior)

Cited by 5 publications

References 0 publications

Etlingera (Zingiberaceae) in Bogor Botanic Gardens: Potential Benefits and Its Conservation Status

Etlingera (Zingiberaceae) in Bogor Botanic Gardens: Potential Benefits and Its Conservation Status

The Activities of Torch Ginger Flower (Etlingera elatior) Ethanol Extract on Degradation of Porphyromonas gingivalis Biofilm as Periodontal Pathogen

Potensi Antioksidan Batang Kecombrang (Bongkot) Bagi Kesehatan

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