Profile, effects, and toxicity of novel psychoactive substances: A systematic review of quantitative studies

Assi, Sulaf; Gulyamova, Nargilya; Ibrahim, Kinda; Kneller, Paul; Osselton, David

doi:10.1002/hup.2607

Cited by 25 publications

(19 citation statements)

References 34 publications

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“…Novel psychoactive substances (NPS) are synthetic substances that have been developed to produce altered states of consciousness and perceptions. The use of NPS has harmful outcomes on both physical and neuropsychiatric symptoms including respiratory depression, cardiac arrest or multiple organ failure (1). NPS users has higher risk of violence, assaultive, or aggressive behavior requiring restraint when compared with non-NPS users (2).…”

Section: Introductionmentioning

confidence: 99%

Prevalence Rates of Personality Disorder and Its Association With Methamphetamine Dependence in Compulsory Treatment Facilities in China

et al. 2018

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Methamphetamine use is popular and rapidly increasing in China, and the co-occurrence of personality disorders has an impact on treatment outcomes and may increase vulnerability of developing dependence. The aim of the present study was to investigate the prevalence rates of personality disorders in methamphetamine users and further explore the association between personality disorders and methamphetamine use status. Five hundred and seventy-seven male methamphetamine users were recruited. The self-developed questionnaire was used for demographics, and a Structural Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) (SCID-I/II) was performed covering psychiatric diagnosis. Our study found the prevalence of antisocial personality disorder in male methamphetamine users was 71.4%, followed by borderline (20.2%) and obsessive-compulsive (17.9%) personality disorder. Borderline and antisocial personality disorders were found to be risk factors of methamphetamine dependence (adjusted odds ratio = 2.891, p = 0.007 and adjusted odds ratio = 1.680, p = 0.042). These findings suggested personality disorders were highly prevalent in male methamphetamine users, and the comorbidity of antisocial and borderline personality disorders are especially associated with methamphetamine dependence.

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Section: Introductionmentioning

confidence: 99%

Prevalence Rates of Personality Disorder and Its Association With Methamphetamine Dependence in Compulsory Treatment Facilities in China

et al. 2018

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“…However, few drivers are convicted for driving under the influence of those types of substances in Norway so the impact of not including them in our study is small. The so-called Novel Psychoactive Substances (245) were neither included in our study. They may reduce driving performance, but are rarely analysed for because of the very quick shift in individual substances available on the market, each expected to be rarely used.…”

Section: Information Biasmentioning

confidence: 99%

Fatally injured drivers in Norway 2005–2015—Trends in substance use and crash characteristics

Valen

Bogstrand

Vindenes

et al. 2019

Traffic Injury Prevention

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Last but not the least, my deepest gratitude goes to Trond Valen for patiently supporting from home this almost never-ending PhD project. You were perfectly right about it not being the best to combine PhD work with an extensive building project and a baby. In addition, several months on the waiting list for kindergarten tipped the schedule even further. I am forever grateful to my extended family members for their help during this time, especially my parents, grandma, and brothers. Ambition is the path to success. Persistence is the vehicle you arrive in. Bill Bradley... often helped by some love and support on the way.

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“…4 Secondly, among the large variety of NPS, some are proven to have "desirable" pharmacological effects, while others are more likely to disappear because of their unpleasant side-effects. [5][6][7] Third, pharmacokinetic studies progressively provide information about the various NPS metabolic pathways and the target analytes to look for, in different biological matrices. Lastly, and most importantly, recent technological developments may make screening analysis for NPS more affordable and effective.…”

Section: Introductionmentioning

confidence: 99%

Should NPS be included in workplace drug testing?

Salomone

Palamar

Vincenti

2020

Drug Testing and Analysis

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Profile, effects, and toxicity of novel psychoactive substances: A systematic review of quantitative studies

Abstract: Despite the unique subjective effects associated with the use of NPS, harmful effects could be severe and/or lethal. Therefore, there is a need to develop research in the area of NPS and promote awareness among healthcare professionals.

Cited by 25 publications

References 34 publications

Prevalence Rates of Personality Disorder and Its Association With Methamphetamine Dependence in Compulsory Treatment Facilities in China

Prevalence Rates of Personality Disorder and Its Association With Methamphetamine Dependence in Compulsory Treatment Facilities in China

Fatally injured drivers in Norway 2005–2015—Trends in substance use and crash characteristics

Should NPS be included in workplace drug testing?

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