Profile of antimicrobial peptides in the bronchoalveolar lavage of patients with interstitial lung diseases

Gómez, Rubén Osuna; Echevarria, Sandra Orozco; Billi, P.; Alcorisa, Silvia Vidal; Villegas, Diego Castillo

doi:10.1183/13993003.congress-2021.oa1208

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Idiopathic Interstitial Pneumonias1

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2022

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“…This five-gene-based signature differentiated significantly between high- and low-risk patient groups (area under the curve (AUC) 0.837). At a protein level, a novel inverse association between pro-fibrotic cytokines and antimicrobial peptides (AMPs) in BAL was identified [ 2 ]. The different AMP profiles in BAL of patients with IPF and other fibrotic ILDs compared with nonfibrotic patients might open up new possibilities for early diagnosis of patients at risk.…”

Section: Idiopathic Interstitial Pneumoniasmentioning

confidence: 99%

ERS International Congress 2021: highlights from the Interstitial Lung Diseases Assembly

et al. 2022

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This article provides an overview of scientific highlights in the field of interstitial lung disease (ILD), presented at the virtual European Respiratory Society Congress 2021. A broad range of topics was discussed this year, ranging from translational and genetic aspects to novel innovations with the potential to improve the patient pathway. Early Career Members summarize a selection of interesting findings from different congress sessions, together with the leadership of Assembly 12 – Interstitial Lung Disease.

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Section: Idiopathic Interstitial Pneumoniasmentioning

confidence: 99%