Prognostic Considerations in the Management of Left Ventricular Aneurysms

Mullen, Donald C.; Posey, L. R.; Gabriel, Roger; Singh, Harjeet; Flemma, Robert J.; Lepley, Derward

doi:10.1016/s0003-4975(10)64166-5

Cited by 50 publications

(3 citation statements)

References 12 publications

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“…The remaining 59 patients (52 men and seven women) with an average age of 52-9 years, consisted of 33 with anterior infarction, 21 with inferior infarction, and five with lateral infarction (Tables 1 and 3). In these 59 patients, 44 had single vessel disease.…”

Section: Methodsmentioning

confidence: 99%

Site and severity of coronary narrowing and infarct size in man.

Hori¹,

Inoue²,

Ohgitani³

et al. 1980

Heart

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The relation between the site and severity of coronary artery lesion and infarct size was investigated in 59 patients with acute myocardial infarction. All patients had no prior myocardial infarction and had at least one significant coronary narrowing (greater than or equal to 75%) in one of the major coronary arteries or in the first diagonal branch. Left ventriculography and selective coronary arteriography were performed on average 2.2 months after the onset of infarction to identify the site and severity of coronary narrowing and to assess the extent of the non-contracting segment (akinetic, dyskinetic, or aneurysmal). Thirty-four of 59 patients were studied enzymatically and total CK released was taken as an indication of infarct size. Non-contracting segment and total CK released in group L-I (narrowing proximal to the first diagonal branch) were significantly larger than those in group L-II (a coronary lesion distal to the branch). The data also indicate that the perfusion area of the first diagonal branch is as large as that of the left anterior descending artery below the first diagonal branch. In contrast to left anterior descending artery disease, the involvement of the right ventricular branch did not significantly influence the infarct size. However, infarct size was significantly larger in eight patients with the left ventricular branch of the right coronary artery supplying the predominantly large area of posterior wall of the left ventricle than in nine patients with small left ventricular branches. It was also shown that the severity of coronary narrowing does not correlate with the infarct size in either left anterior descending or right coronary artery disease.

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Section: Methodsmentioning

confidence: 99%

Site and severity of coronary narrowing and infarct size in man.

Hori¹,

Inoue²,

Ohgitani³

et al. 1980

Heart

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show abstract

“…Since the early days of cardiac surgery until now, most series in the literature have reported a high mortality rate for the surgical treatment of left ventricular aneurysm, ranging from 2 to 19% (mean 9.9%) 9,15,[20][21][22][23][24][25][26][27][28][29][30][31][32][33] .…”

Section: Discussionmentioning

confidence: 99%

Short-term follow-up of patients after aneurysmectomy of the left ventricle

Silveira¹,

Leite²,

Soares³

et al. 2000

Arq. Bras. Cardiol.

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“…For example, the frequency of left ventricular thrombi in aneurysms seen at post mortem can range between 14 to 68%, which is consistent with findings at aneurysmectomy (50_95%).1 However, the reported incidences of systemic thromboembolism in patients with left ventricular aneurysm demonstrate a wide range, from 0 to 52%. 1,[3][4][5] Thus, although it is generally considered that patients with chronic aneurysms (longer than three months) are at low thromboembolic risk, a high proportion still have intracardiac thrombus formation. There is thus some debate on the likelihood of thromboembolism.1…”

Section: Mechanisms and Factors Contributing To Thromboembolismmentioning

confidence: 99%

Intracardiac thrombus formation in cardiac impairment: the role of anticoagulant therapy

Lip

1996

Postgraduate Medical Journal

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Summary The presence of intracardiac thrombus has been associated with many diseases and clinical states, although cardiac impairment is commonly also present. Despite this, there continues to be a lack of consensus on which patients with cardiac impairment should have anticoagulant therapy. This review discusses the relationship between thromboembolism and cardiac impairment secondary to ischaemic heart disease, and suggests possible mechanisms, methods of diagnosis and therapeutic strategies for anticoagulation in such patients. In particular, warfarin has been established as thromboprophylaxis in certain subgroups of patients with cardiac impairment secondary to ischaemic heart disease. A large-scale randomised controlled trial in ambulant patients with cardiac impairment to evaluate the effectiveness of anticoagulant therapy and antiplatelet therapy is, however, long overdue.

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Prognostic Considerations in the Management of Left Ventricular Aneurysms

Cited by 50 publications

References 12 publications

Site and severity of coronary narrowing and infarct size in man.

Site and severity of coronary narrowing and infarct size in man.

Short-term follow-up of patients after aneurysmectomy of the left ventricle

Intracardiac thrombus formation in cardiac impairment: the role of anticoagulant therapy

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