Progress in Ionic Liquids as Reaction Media, Monomers and Additives in High-Performance Polymers

He, Dannong; Liu, Zheng­ping; Huang, Liyan

doi:10.5772/intechopen.86472

Cited by 3 publications

(2 citation statements)

References 150 publications

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“…Ionic strength seems to be advantageous for ionic drug attachment [ 8 , 9 ]. In these cases, the carriers contain ionic groups, which are usually provided by ionic liquids (IL) as suitable (co)monomers introduced into the polymer chain [ 10 , 11 , 12 ]. Many of them are known as biocompatible, especially those based on choline chloride with cationic trimethylammonium groups [ 13 , 14 , 15 , 16 , 17 ].…”

Section: Introductionmentioning

confidence: 99%

Biological In Vitro Evaluation of PIL Graft Conjugates: Cytotoxicity Characteristics

Niesyto

Łyżniak

Skonieczna

et al. 2021

IJMS

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In vitro cytotoxicity of polymer-carriers, which in the side chains contain the cholinum ionic liquid units with chloride (Cl) or pharmaceutical anions dedicated for antituberculosis therapy, i.e., p-aminosalicylate (PAS) and clavulanate (CLV), was investigated. The carriers and drug conjugates were examined, in the concentration range of 3.125–100 μg/mL, against human bronchial epithelial cells (BEAS-2B) and adenocarcinomic human alveolar basal epithelial cells (A549) as an experimental model cancer cell line possibly coexisting in tuberculosis. The cytotoxicity was evaluated by MTT test and confluency index, as well as by the cytometric analyses, including Annexin-V FITC apoptosis assay. The polymer systems showed supporting activity towards the normal cells and no tumor progress, especially at the highest concentration (100 μg/mL). The analysis of cell death did not show meaningful changes in the case of the BEAS-2B, whereas in the A549 cell line, the cytostatic activity was observed, especially for the drug-free carriers, causing death in up to 80% of cells. This can be regulated by the polymer structure, including the content of cationic units, side-chain length and density, as well as the type and content of pharmaceutical anions. The results of MTT tests, confluency, as well as cytometric analyses, distinguished the polymer systems with Cl/PAS/CLV containing 26% of grafting degree and 43% of ionic units or 46% of grafting degree and 18% of ionic units as the optimal systems.

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Section: Introductionmentioning

confidence: 99%

Biological In Vitro Evaluation of PIL Graft Conjugates: Cytotoxicity Characteristics

Niesyto

Łyżniak

Skonieczna

et al. 2021

IJMS

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“…The already mentioned ionic liquids are no longer a scientific sensation but are becoming the objects of intensive research even in the industry [ 24 ]. They have also been reported to have antistatic properties, rendering them an object of interest in this paper [ 25 , 26 , 27 , 28 , 29 , 30 ].…”

Section: Introductionmentioning

confidence: 99%

New Hybrid Polyurea-Polyurethane Elastomers with Antistatic Properties and an Influence of Various Additives on Their Physicochemical Properties

Kosiński

Gonsior²,

Krzyz̈anowski³

et al. 2021

Molecules

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Polyurea is a synthetic high-strength elastomeric material that can be sprayed as a coating over existing structures in order to protect against weathering effects. It is ideal for anti-corrosion protection and is characterized by excellent mechanical properties and adhesion to various surfaces. Further development of this technology may allow obtaining new coatings with improved antistatic properties, which would be an excellent alternative compared to used antistatic epoxy paints. This paper will examine the influence of tetraalkylammonium salt (1), potassium hexafluorophosphate solution (2) and imidazolium-based ionic liquid (3) on the improvement of antistatic properties of the polyurea-polyurethane coatings. In addition, the modified samples were also verified in terms of changes in mechanical properties and the appearance of functional groups other than in the reference sample, as well as surface defects that may arise due to incompatibility of the antistatic additive with the polymer matrix. In order to obtain information about the properties mentioned above, the electrical resistance was determined, the tensile strength and elongation were measured, FT-IR spectra were made, and images were taken with the use of scanning electron microscopy. The conducted research showed that the antistatic properties of the tested hybrid coatings could be improved, but their use may be associated with certain limitations that should be taken into account when designing such materials.

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Effect of the Molecularly Imprinted Polymer Component Ratio on Analytical Performance

et al. 2020

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Progress in Ionic Liquids as Reaction Media, Monomers and Additives in High-Performance Polymers

Cited by 3 publications

References 150 publications

Biological In Vitro Evaluation of PIL Graft Conjugates: Cytotoxicity Characteristics

Biological In Vitro Evaluation of PIL Graft Conjugates: Cytotoxicity Characteristics

New Hybrid Polyurea-Polyurethane Elastomers with Antistatic Properties and an Influence of Various Additives on Their Physicochemical Properties

Effect of the Molecularly Imprinted Polymer Component Ratio on Analytical Performance

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