Progress on Developing Adaptive Optics–Optical Coherence Tomography for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts

Zawadzki, Robert J.; Capps, Arlie G.; Kim, Dae Yu; Panorgias, Athanasios; Stevenson, Scott B.; Hamann, Bernd; Werner, John S.

doi:10.1109/jstqe.2013.2288302

Cited by 26 publications

(15 citation statements)

References 95 publications

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“…Although high speed AO-OCT systems and retinal tracking techniques are now available and help reduce image artifacts (Ishikawa et al, 2006; Kocaoglu et al, 2014a; Kocaoglu et al, 2014b; Zawadzki et al, 2014), it is still unclear whether these provide better ability to detect disease (Menke et al, 2009). Additionally, novel post-processing methods (Jonnal et al, 2012), and high-speed complementary metal oxide semiconductor (CMOS) detectors have been employed to reduce motion artifacts (Kocaoglu et al, 2011b; Kocaoglu et al, 2011c; Salas et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Adaptive optics optical coherence tomography in glaucoma

Dong

Wollstein

Wang

et al. 2017

Progress in Retinal and Eye Research

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Since the introduction of commercial optical coherence tomography (OCT) systems, the ophthalmic imaging modality has rapidly expanded and it has since changed the paradigm of visualization of the retina and revolutionized the management and diagnosis of neuro-retinal diseases, including glaucoma. OCT remains a dynamic and evolving imaging modality, growing from time-domain OCT to the improved spectral-domain OCT, adapting novel image analysis and processing methods, and onto the newer swept-source OCT and the implementation of adaptive optics (AO) into OCT. The incorporation of AO into ophthalmic imaging modalities has enhanced OCT by improving image resolution and quality, particularly in the posterior segment of the eye. Although OCT previously captured in-vivo cross-sectional images with unparalleled high resolution in the axial direction, monochromatic aberrations of the eye limit transverse or lateral resolution to about 15-20 μm and reduce overall image quality. In pairing AO technology with OCT, it is now possible to obtain diffraction-limited resolution images of the optic nerve head and retina in three-dimensions, increasing resolution down to a theoretical 3 μm3. It is now possible to visualize discrete structures within the posterior eye, such as photoreceptors, retinal nerve fiber layer bundles, the lamina cribrosa, and other structures relevant to glaucoma. Despite its limitations and barriers to widespread commercialization, the expanding role of AO in OCT is propelling this technology into clinical trials and onto becoming an invaluable modality in the clinician's arsenal.

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Section: Introductionmentioning

confidence: 99%

Adaptive optics optical coherence tomography in glaucoma

Dong

Wollstein

Wang

et al. 2017

Progress in Retinal and Eye Research

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“…OCT systems for example, which are not part of this review, can benefit tremendously from AO. Impressive work is already underway in several labs (Felberer et al 2014, Jonnal et al 2012, Zawadzki et al 2014, Zawadzki et al 2009). …”

Section: 0 Discussionmentioning

confidence: 99%

Adaptive Optics Ophthalmoscopy

Roorda

Duncan

2015

Annu. Rev. Vis. Sci.

147

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This review starts with a brief history and description of adaptive optics (AO) technology, followed by a showcase of the latest capabilities of AO systems for imaging the human retina and an extensive review of the literature on where AO is being used clinically. The review concludes with a discussion on future directions and guidance on usage and interpretation of images from AO systems for the eye.

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“…Zawadzki et al (2014) use a combination of AO-SLO and AO-OCT for correcting the transverse eye motion artifacts. For OCT they used a 836 nm light with a bandwidth of 112 nm and for SLO, a 683.4 nm light with a bandwidth of 8.2 nm .…”

Section: Methodsmentioning

confidence: 99%

Involuntary eye motion correction in retinal optical coherence tomography: Hardware or software solution?

Baghaie

D’Souza

2017

Medical Image Analysis

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In this paper, we review state-of-the-art techniques to correct eye motion artifacts in Optical Coherence Tomography (OCT) imaging. The methods for eye motion artifact reduction can be categorized into two major classes: 1) hardware-based techniques and 2) software-based techniques. In the first class, additional hardware is mounted onto the OCT scanner to gather information about the eye motion patterns during OCT data acquisition. This information is later processed and applied to the OCT data for creating an anatomically correct representation of the retina, either in an offline or online manner. In software based techniques, the motion patterns are approximated either by comparing the acquired data to a reference image, or by considering some prior assumptions about the nature of the eye motion. Careful investigations done on the most common methods in the field provides invaluable insight regarding future directions of the research in this area. The challenge in hardware-based techniques lies in the implementation aspects of particular devices. However, the results of these techniques are superior to those obtained from software-based techniques because they are capable of capturing secondary data related to eye motion during OCT acquisition. Software-based techniques on the other hand, achieve moderate success and their performance is highly dependent on the quality of the OCT data in terms of the amount of motion artifacts contained in them. However, they are still relevant to the field since they are the sole class of techniques with the ability to be applied to legacy data acquired using systems that do not have extra hardware to track eye motion.

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Progress on Developing Adaptive Optics–Optical Coherence Tomography for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts

Cited by 26 publications

References 95 publications

Adaptive optics optical coherence tomography in glaucoma

Adaptive optics optical coherence tomography in glaucoma

Adaptive Optics Ophthalmoscopy

Involuntary eye motion correction in retinal optical coherence tomography: Hardware or software solution?

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