2014
DOI: 10.1183/09031936.00172113
|View full text |Cite
|
Sign up to set email alerts
|

Prolonged shedding of rhinovirus and re-infection in adults with respiratory tract illness

Abstract: Rhinovirus infections occur frequently throughout life and have been reported in about onethird of asymptomatic cases. The clinical significance of sequential rhinovirus infections remains unclear.To determine the incidence and clinical relevance of sequential rhinovirus detections, nasopharyngeal samples from 2485 adults with acute cough/lower respiratory illness were analysed. Patients were enrolled prospectively by general practitioners from 12 European Union countries during three consecutive years (2007)(… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

5
73
0
1

Year Published

2014
2014
2023
2023

Publication Types

Select...
8
2

Relationship

1
9

Authors

Journals

citations
Cited by 68 publications
(79 citation statements)
references
References 32 publications
5
73
0
1
Order By: Relevance
“…In our study it should be underlined that all eight HAP cases with long-term shedding of community-acquired viruses involved immunocompromised patients with coinfection with other pathogens. Shedding of rhinoviruses for more than 4 weeks is not uncommon even in immunocompetent individuals [27] and especially in patients with immunodeficiency in whom chronic rhinovirus carriage for as long as 4-12 months has been documented [28]. The significance of rhinovirus detection in respiratory specimens from pneumonia patients is a subject of some debate.…”
Section: Discussionmentioning
confidence: 99%
“…In our study it should be underlined that all eight HAP cases with long-term shedding of community-acquired viruses involved immunocompromised patients with coinfection with other pathogens. Shedding of rhinoviruses for more than 4 weeks is not uncommon even in immunocompetent individuals [27] and especially in patients with immunodeficiency in whom chronic rhinovirus carriage for as long as 4-12 months has been documented [28]. The significance of rhinovirus detection in respiratory specimens from pneumonia patients is a subject of some debate.…”
Section: Discussionmentioning
confidence: 99%
“…Several viruses were detected in sufficient numbers to investigate their epidemiology. Rhinovirus characteristics, including high case numbers, broad age range and distribution of family members who were index cases, propensity to transmit within households, and year-round detection, correspond with high infectiousness and extensive genetic diversity [27]. Influenza viruses have less extensive genetic diversity, but age-associations were consistent with greater antigenic drift for A/H3N2 compared to A/H1N1 and B [11,13,28,29].…”
Section: Discussionmentioning
confidence: 99%
“…For HRV, the rates of prolonged shedding (same genotype in 35%) versus re-infection (other genotype) in the GRACE study have been further investigated [24].…”
Section: Importance Of Respiratory Viruses Including Newly Detectedmentioning
confidence: 99%