Prophylactic Low-energy Laser Application to Prevent Chemoradiation-induced Oral Mucositis: A Prospective and Randomized Trial

Oral Glutamine May Have No Clinical Benefits to Prevent Radiation-Induced Oral Mucositis in Adult Patients With Head and Neck Cancer: A Meta-Analysis of Randomized Controlled Trials

“…At present, there are plenty of published studies exploring different ways for the prevention of OM, such as laser therapy or several nonpharmacologic methods (12)(13)(14). But there is still lack of definitive conclusion about the effect of these interventions.…”

Supportive care in head and neck oncology

“…In both groups, it was allowed to receive basic oral care and analgesics. The number of patients diagnosed with grade 3 or 4 oral mucositis treated with LLL was significantly lower in week 4 (P ¼ 0.04) and more patients treated with placebo had radiation therapy interruptions due to mucositis (6 versus 0, P ¼ 0.02), which may translate in better chemoradiation efficacy and tolerability [14].…”