2018
DOI: 10.1161/strokeaha.117.019189
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Prospective Study of Fasting Blood Glucose and Intracerebral Hemorrhagic Risk

Abstract: Background and Purpose Although diabetes mellitus is an established independent risk factor for ischemic stroke, the association between fasting blood glucose and intracerebral hemorrhage is limited and inconsistent. The objectives of the current study was to examine the potential impact of long-term fasting blood glucose concentration on subsequent risk of intracerebral hemorrhage. Methods This prospective study included 96,110 participants of the Kailuan study, living in Kailuan community, Tangshan city, C… Show more

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Cited by 46 publications
(46 citation statements)
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“…Finally, 141 articles were excluded because they were animal studies (n = 9), unable to provide information (n = 120) or without a full publication (n = 12). The remaining 12 studies were enrolled in the meta‐analysis . There were 4 prospective cohort studies, 6 cross‐sectional studies and 2 with both cohort and cross‐sectional data studies .…”
Section: Resultsmentioning
confidence: 99%
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“…Finally, 141 articles were excluded because they were animal studies (n = 9), unable to provide information (n = 120) or without a full publication (n = 12). The remaining 12 studies were enrolled in the meta‐analysis . There were 4 prospective cohort studies, 6 cross‐sectional studies and 2 with both cohort and cross‐sectional data studies .…”
Section: Resultsmentioning
confidence: 99%
“…The remaining 12 studies were enrolled in the meta‐analysis . There were 4 prospective cohort studies, 6 cross‐sectional studies and 2 with both cohort and cross‐sectional data studies . For continuous HbA 1c , 4 cohort studies investigated different structural brain abnormalities: 2 involved white matter hyperintensities, 3 involved infarct, and 2 involved brain volume).…”
Section: Resultsmentioning
confidence: 99%
“…An occult bleed was defined as an acute drop in hemoglobin with positive fecal occult blood test and negative upper and lower endoscopies. ICH was diagnosed according to the World Health Organization criteria [19], and confirmed by head computed tomography (CT) or magnetic resonance imaging (MRI). Major bleeding was diagnosed according to the standardized bleeding definitions for cardiovascular clinical trials by the American Bleeding Academic Research Consortium, and types 3 and 4 were defined as major bleeding [20].…”
Section: Definitionsmentioning
confidence: 99%
“…Overall, the current evidence supports that early intensive blood pressure lowering is safe and feasible, and is associated with a modestly better functional outcome. Thirdly, hyperglycemia on admission is associated with an increased 28-day case fatality in both nondiabetic and diabetic patients with ICH [19]. Therefore, hyperglycemia should be controlled adequately, glucose level should be monitored regularly and both hyperglycemia and hypoglycemia should be avoided [19,54].…”
Section: Management Of Ich In the Elderlymentioning
confidence: 99%
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