Protective Effects and Mechanisms of <i>Pourthiaea villosa</i> (Thunb.) Decne. Extract on Hydrogen Peroxide-Induced Skin Aging in Human Dermal Fibroblasts

Choi, Sun‐Il; Lee, Jong Seok; Lee, Sarah; Cho, Bong‐Yeon; Choi, Seung‐Hyun; Han, Xionggao; Sim, Wan‐Sup; Kim, Young‐Cheul; Lee, Boo-Yong; Kang, Il‐Jun; Lee, Ok‐Hwan

doi:10.1089/jmf.2018.4379

Cited by 6 publications

(8 citation statements)

References 33 publications

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“…The downregulation of MMP-2 expression was described after treatments with plant extracts of Cassia fistula [ 43 ], Magnolia officinalis [ 29 ], and Pourthiaea villosa [ 51 ];…”

Section: Skin Anti-aging Natural Products By Acting On the Skin Elast...mentioning

confidence: 99%

“…A reduction in other metalloproteinases was observed after treatments with plant extracts of Penthorium chinense [ 47 ], Piper cambodianum [ 34 ], Pousthiaea villosa [ 51 ] and Syzygium aromaticum [ 50 ];…”

Section: Skin Anti-aging Natural Products By Acting On the Skin Elast...mentioning

confidence: 99%

“…Among the plant extracts that modulated oxidative stress, it is important to highlight those herbal preparations with a range of antioxidant properties by different methods. Camelia sinensis also upregulated SOD, CAT, and GPX in human dermal fibroblasts and increased the NRf2 transcriptional level and nuclear translocation [ 38 ], whereas Pourthiaea villosa and Ulmus macrocarpa increased SOD1 and SOD 2 protein levels and inhibited the cellular senescence induced by hydrogen peroxide [ 51 , 61 ].…”

Section: Skin Anti-aging Natural Products By Acting On the Skin Oxida...mentioning

confidence: 99%

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Recent Advances in Herbal-Derived Products with Skin Anti-Aging Properties and Cosmetic Applications

2022

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Although aesthetic benefits are a desirable effect of the treatment of skin aging, it is also important in controlling several skin diseases, mainly in aged people. The development of new dermocosmetics has rapidly increased due to consumers’ demand for non-invasive products with lower adverse effects than those currently available on the market. Natural compounds of plant origin and herbal-derived formulations have been popularized due to their various safe active products, which act through different mechanisms of action on several signaling pathways for skin aging. Based on this, the aim of the review was to identify the recent advances in herbal-derived product research, including herbal formulations and isolated compounds with skin anti-aging properties. The studies evaluated the biological effects of herbal-derived products in in vitro, ex vivo, and in vivo studies, highlighting the effects that were reported in clinical trials with available pharmacodynamics data that support their protective effects to treat, prevent, or control human skin aging. Thus, it was possible to identify that gallic and ferulic acids and herbal formulations containing Thymus vulgaris, Panax ginseng, Triticum aestivum, or Andrographis paniculata are the most promising natural products for the development of new dermocosmetics with skin anti-aging properties.

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“…The downregulation of MMP-2 expression was described after treatments with plant extracts of Cassia fistula [ 43 ], Magnolia officinalis [ 29 ], and Pourthiaea villosa [ 51 ];…”

Section: Skin Anti-aging Natural Products By Acting On the Skin Elast...mentioning

confidence: 99%

Section: Skin Anti-aging Natural Products By Acting On the Skin Elast...mentioning

confidence: 99%

Section: Skin Anti-aging Natural Products By Acting On the Skin Oxida...mentioning

confidence: 99%

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Recent Advances in Herbal-Derived Products with Skin Anti-Aging Properties and Cosmetic Applications

2022

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“…In this review, it was observed that the HPLC was employed in most of the studies to identify and quantify the bioactive compounds in plant extracts. Out of the 30 publications that were reviewed in Table 2, 12 research groups performed bioactive compound identification (and/or quantification) using HPLC with detectors such as diode-array detection (DAD) or photodiode-array detection (PDA), 1 used ultra-HPLC (UHPLC) 34 and 2 of them were coupled with MS in the analysis. 33,55 HPLC is preferred could be due to majority of them carried out extraction using polar solvents such as ethanol.…”

Section: Instrumentation In the Identification Of Bioactive Compoundsmentioning

confidence: 99%

Plant polyphenols as green sunscreen ingredients: A systematic review

Suk

Gew

2022

J of Cosmetic Dermatology

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The sun is the source of energy for living things on Earth. It emits electromagnetic radiation of various wavelengths including infrared, visible, and ultraviolet light. Ultraviolet radiation (UVR) is divided into three regions: UVA, UVB, and UVC. UVA region (320-400 nm) penetrates deep into the skin through the epidermis and dermis, which are responsible for skin darkening, photoaging, and DNA damage. UVB region (280-320 nm) acts mainly on the epidermis, which is the major cause of sunburn and skin cancer. The UVC region (200-280 nm) is less hazardous because the radiation is filtered by the stratospheric ozone layer. 1,2 Excessive exposure to UVR has harmful effects on human skin which potentially causes skin damage. Therefore, photoprotection from both UVA and UVB radiation is more of a concern for the development of sunscreen.Sunscreen plays a critical role in reducing the incidence of UVinduced skin problems with its ability to absorb, scatter, and reflect the harmful radiation, thus creating a chemical barrier on the skin that avoids skin damage caused by UVR. 3 The common ingredients in current sunscreen include organic compounds such as benzophenones, avobenzone, and p-aminobenzoic acid derivatives; inorganic compounds such as zinc oxide, magnesium oxide, titanium dioxide, and kaolin. 4 The long-term use of sunscreen consisting of these ingredients has been reported to cause negative health effects such as dermatitis, phototoxic, photoallergic, photogenotoxicity, and systemic toxicity. [5][6][7] Some studies also reported the negative environmental effect of chemical ingredients in sunscreen such as the damage to coral reefs that leads to ecosystem disruption. 8 Therefore, it is important to develop an effective sunscreen with minimum side effects.

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“…Cells were pre-treated with the extracts and then exposed to the ROS-inducing stressor (H2O2 or AAPH). The ROS detection reagent, DCFH-DA, was added and detection for ROS was performed by fluorimetry [ 76 , 77 , 79 , 80 ]. All extracts inhibited intracellular ROS production by protecting against oxidative stress.…”

Section: The Impact Of Reactive Oxygen Species On Dermal Fibroblastsmentioning

confidence: 99%

Antioxidant Properties of Plant-Derived Phenolic Compounds and Their Effect on Skin Fibroblast Cells

et al. 2021

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Plants are rich sources of a diverse range of chemicals, many of which have significant metabolic activity. One large group of secondary compounds are the phenolics, which act as inter alia potent reactive oxygen scavengers in cells, including fibroblasts. These common dermis residue cells play a crucial role in the production of extracellular matrix components, such as collagen, and maintaining the integrity of connective tissue. Chronic wounds or skin exposure to UV-irradiation disrupt fibroblast function by the generation of reactive oxygen species, which may damage cell components and modify various signaling pathways. The resulting imbalance may be reversed by the antioxidant activity of plant-derived phenolic compounds. This paper reviews the current state of knowledge on the impact of phenolics on fibroblast functionality under oxidative stress conditions. It examines a range of compounds in extracts from various species, as well as single specific plant-derived compounds. Phenolics are a good candidate for eliminating the causes of skin damage including wounds and aging and acting as skin care agents.

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Protective Effects and Mechanisms of Pourthiaea villosa (Thunb.) Decne. Extract on Hydrogen Peroxide-Induced Skin Aging in Human Dermal Fibroblasts

Cited by 6 publications

References 33 publications

Recent Advances in Herbal-Derived Products with Skin Anti-Aging Properties and Cosmetic Applications

Recent Advances in Herbal-Derived Products with Skin Anti-Aging Properties and Cosmetic Applications

Plant polyphenols as green sunscreen ingredients: A systematic review

Antioxidant Properties of Plant-Derived Phenolic Compounds and Their Effect on Skin Fibroblast Cells

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