Pruritus ani and perianal eczema as a manifestation of systemic contact dermatitis

Hadasik, Karolina; Bergler‐Czop, Beata; Miziołek, Bartosz; Salwowska, Natalia; Skrzypek‐Salamon, Alina

doi:10.5114/ada.2017.67085

Cited by 5 publications

(2 citation statements)

References 11 publications

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“…According to the previous studies, one of the causes of perianal eczema and pruritus ani may include the manifestations of nickel-induced systemic dermatitis. [ 2 ] Patch test has shown that certain components in wet wipes, such as methylchloroisothiazolinone, are the main allergens of perianal eczema. [ 3 ] The majority of typical clinical manifestations include severe itching and other symptoms, such as erythema, pimples, blisters, erosions, exudates, crusts caused by scratching, thickening, and roughening of the anus skin.…”

Section: Introductionmentioning

confidence: 99%

Differences in microbiota between acute and chronic perianal eczema

Ma¹,

Lü²,

Yang

et al. 2021

Medicine

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Microbiota has been suggested to play a role in patients with intestinal and cutaneous diseases. However, the profiling of perianal eczema microbiota has not been described. We have explored the general profile and possible differences between acute and chronic perianal eczema. A total of 101 acute perianal eczema (APE) and 156 chronic perianal eczema (CPE) patients were enrolled in this study and the perianal microbiota was profiled via Illumina sequencing of the 16S rRNA V4 region. The microbial α-diversity and structure are similar in APE and CPE patients; however, the perianal microbiota of the APE patients had a higher content of Staphylococcus (22.2%, P < .01) than that of CPE patients. Top10 genera accounting for more than 60% (68.81% for APE and 65.47% for CPE) of the whole microbiota, including Prevotella , Streptococcus , and Bifidobacterium , show an upregulation trend in the case of APE without reaching statistically significant differences. This study compared the microbiota profiles of acute and chronic perianal eczema. Our results suggest that the microbiota of acute perianal eczema patients is enriched in Staphylococcus compared with that in the chronic group. Our findings provide data for further studies.

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Section: Introductionmentioning

confidence: 99%

Differences in microbiota between acute and chronic perianal eczema

Ma¹,

Lü²,

Yang

et al. 2021

Medicine

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“…SCD caused by nickel is Systemic Nickel Allergy Syndrome (SNAS) which we consider a major factor in atopy. Sources of nickel exposure include dental materials, dietary intake, and jewelry [2,[7][8][9][10][11][12][13][14][15]. In a case series of 20 patients with allergic rhinitis, 11 of whom also had asthma, Brera reported improvement in nasal and bronchial symptoms with a low nickel diet [16].…”

Section: Introductionmentioning

confidence: 99%

Refractory Systemic Nickel Allergy Syndrome Management: 5 Cases and Chart Review Survey from an Integrative Medical Practice

Chung¹,

Bandomer²,

Cafaro³

et al. 2023

Preprint

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Five patients with standard medical treatment-resistant symptoms of skin lesions, ear infections, allergic rhinitis, nasal congestion, asthma, heartburn, and failure to thrive were success- fully treated with an integrative medicine assessment and integrative medicine treatment approach. The integrative medicine assessment method of autonomic response testing enabled the identifica- tion of nickel sensitivity as a common element in these patients. It guided the use of the integrative medicine therapies of low dose immunotherapy, gamma linoleic acid supplementation, chelation, dietary nickel restriction, and removal of nickel containing dental and cosmetic appliances. A chart review of 151 patients indicated a strong association of nickel and the simultaneous presence of skin lesions.

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Systemic Contact Dermatitis

Veien¹

2020

Contact Dermatitis

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Pruritus ani and perianal eczema as a manifestation of systemic contact dermatitis

Cited by 5 publications

References 11 publications

Differences in microbiota between acute and chronic perianal eczema

Differences in microbiota between acute and chronic perianal eczema

Refractory Systemic Nickel Allergy Syndrome Management: 5 Cases and Chart Review Survey from an Integrative Medical Practice

Systemic Contact Dermatitis

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