Pseudomaladie de Kaposi secondaire à une malformation artérioveineuse superficielle : syndrome de Stewart-Bluefarb

Alioua, Z.; Lamsyah, H.; Sbai, Mohamed Ali; Rimani, M.; Baba, Noureddine; Ghfir, M.; Sedrati, O.

doi:10.1016/j.annder.2007.04.004

Cited by 5 publications

(5 citation statements)

References 14 publications

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“…Managing this condition always involves a multidisciplinary approach, as was the case with our patient. This observation draws attention to clinicians when encountering any angiomatous mass in the extremities, always investigating the presence or absence of the notion of pathergy, which, once present, may suggest a diagnosis other than Kaposi's disease, as was the case with our patient, and always conducting an appropriate vascular examination to identify venous insufficiency [7][8][9] .…”

Section: Argumentmentioning

confidence: 62%

Multiple acroangiodermatitis of the left big toe: A case report from the university clinic of dermatology-venereology of the national university hospital center Hubert Koutoukou MAGA of Cotonou in Benin

Kitha,

Dégboé,

Gomez

et al. 2024

Int. J.Dermatol. Sci.

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Angioacrodermatitis, or Pseudo-Kaposi sarcoma, is a vascular anomaly observed at the extremities in patients with venous insufficiency, often triggered by trauma. Acroangiodermatitis may resemble Kaposi's sarcoma, but unlike Kaposi's sarcoma, acroangiodermatitis is not characterized by progressive changes, and there is a lack of spindle cells and vessels resembling slits on histopathological analysis. Thus, in clinical practice, it is important to recognize acroangiodermatitis and exclude Kaposi's sarcoma, as there may sometimes be similarity with this entity. Topical treatment with neutral corticosteroid preparations and local is often helpful. 35-year-old patient, a communications advisor, who consulted for asymptomatic solid lesions on the left big toe, evolving continuously for 10 years, progressively increasing in size. A toe injury preceded the onset of the lesions. He had no other medical history. On examination, there were angioma-like masses, firm with a discretely keratotic surface, welldefined, painless on palpation adherent to deep and superficial planes, of variable shape, numbering four (4), measuring 2 cm x 4 cm, the largest of which had a parrot beak appearance. There was a discreet increase in local temperature, but no bruit or thrill was noted. The HIV retroviral serology and blood glucose levels were normal. Histopathology revealed vascular proliferation with dilated luminal vessels separated by fibrosis. The diagnosis of acroangiodermatitis or pseudo-Kaposi sarcoma was made. Acroangiodermatitis is a vascular pathology that presents a differential diagnostic challenge with Kaposi's disease. Histopathology is the cornerstone of diagnosis.

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Section: Argumentmentioning

confidence: 62%

Multiple acroangiodermatitis of the left big toe: A case report from the university clinic of dermatology-venereology of the national university hospital center Hubert Koutoukou MAGA of Cotonou in Benin

Kitha,

Dégboé,

Gomez

et al. 2024

Int. J.Dermatol. Sci.

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“…Stewart-Bluefarb syndrome is a form of pseudo-Kaposi corresponding to reactional posttraumatic angiodysplasia. It is clinically and histologically similar to MK [9].…”

Section: Introductionmentioning

confidence: 83%

“…Its pathogenesis is not clearly elucidated, but it suggests that any condition favoring the increase of venous pressure produces a retrograde blood flow that can stimulate, especially in fragile anatomical areas, the proliferation of endothelial and fibroblastic cells under the action of the vascular endothelium growth factor (VEGF). e contributing factors may be trauma, as is the case in our patient, an arteriovenous fistula during hemodialysis, vascular surgery, or a significant hormonal period such as puberty or pregnancy [9,13].…”

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confidence: 84%

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Epidemic, Endemic, or Stewart–Bluefarb? When Several Forms of Kaposi Seem to Dispute Paternity

Adégbidi

Degboe

Akpadjan

et al. 2020

Case Reports in Dermatological Medicine

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The role of human herpes virus 8 (HHV8) is demonstrated in the occurrence of Kaposi’s disease, but the role of cofactors is still hardly known. We report a case of Kaposi’s disease which occurred 10 years after a local trauma in an HIV-positive patient from Central Africa. A 38-year-old female, from and living in Central Africa, consulted for angiomatous papulo-nodules associated with purple-colored macules and painful lymphoedema of the right leg and foot that had been developing for 6 months. She reported a history of posttraumatic lymphoedema of the affected limb as a result of a road accident that occurred ten years earlier. The mucous were healthy. There was no sign of systemic lesions. The diagnosis of Kaposi’s disease was evoked with, in differential, a Stewart–Bluefarb syndrome-type of pseudo-Kaposi and an epidemic Kaposi disease. Retroviral serology was positive to HIV1 with a CD4 count of 600 cells/mm3. Histopathology of the lesions and duplex ultrasonography could not be performed. The rest of the biological assessment was without particularity. The diagnosis of epidemic Kaposi’s disease associated with cofactors involved in endemic Kaposi’s disease and Stewart–Bluefarb syndrome was retained. An antiretroviral treatment (emtricitabine, tenofovir, and efavirenz) allowed to obtain after 6 months a noticeable improvement of the lesions and a disappearance of the pain with however the persistence of a residual lymphoedema. This is a special case of Kaposi’s disease that seems to involve several factors. The role of cofactors in Kaposi’s disease remains to be elucidated.

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“…A large number of entities require distinction from KS including cutaneous metastasis, bacillary angiomatosis, pyogenic granuloma, hemangiomas, angiokeratoma, blue rubber bleb nevus syndrome, melanocytic lesions and stasis dermatitis [6,7,8,9,10,11,12,13,14,15,16,17,18]. …”

Section: Introductionmentioning

confidence: 99%

Preliminary Evaluation of in vivo Reflectance Confocal Microscopy Features of Kaposi’s Sarcoma

et al. 2010

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Background: Kaposi’s sarcoma (KS) is an unusual, clinically polymorphic, vascular neoplasm with genetic, infectious, environmental and immunological pathogenesis. Reflectance confocal microscopy (RCM) made in vivo noninvasive imaging of the skin possible and has been used for the evaluation of several skin diseases offering important microscopic information. Objective: The purpose of our study is to describe the RCM features of KS and correlate them with histopathology evaluating the effective prediction attitude and repeatability of RCM. Methods: Twelve KS lesions underwent RCM followed by histological examination. Data obtained were statistically correlated. Results: Analysis of the incidence of 11 selected microscopic criteria (by RCM and optical histology: inflammatory cells in the epidermis and in the dermis, single or in aggregates; spindle cells; stroma; anastomosing, newborn, increased number and dilated vessels; extravasated erythrocytes; deposits of hemosiderin) was performed disclosing a good correlation and high sensitivity of RCM. Conclusion: In our study RCM seems to provide high accuracy to predict histological findings, demonstrating its possible role in the management of patients affected by KS.

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Pseudomaladie de Kaposi secondaire à une malformation artérioveineuse superficielle : syndrome de Stewart-Bluefarb

Cited by 5 publications

References 14 publications

Multiple acroangiodermatitis of the left big toe: A case report from the university clinic of dermatology-venereology of the national university hospital center Hubert Koutoukou MAGA of Cotonou in Benin

Multiple acroangiodermatitis of the left big toe: A case report from the university clinic of dermatology-venereology of the national university hospital center Hubert Koutoukou MAGA of Cotonou in Benin

Epidemic, Endemic, or Stewart–Bluefarb? When Several Forms of Kaposi Seem to Dispute Paternity

Preliminary Evaluation of in vivo Reflectance Confocal Microscopy Features of Kaposi’s Sarcoma

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