Pseudomonas syringae pv. tomato hijacks the Arabidopsis abscisic acid signalling pathway to cause disease

Torres-Zabala, Marta de; Truman, William; Bennett, Mark H.; Lafforgue, Guillaume; Mansfıeld, John W.; Rodriguez, Pedro L.; Bögre, László; Grant, Murray

doi:10.1038/sj.emboj.7601575

Cited by 491 publications

(500 citation statements)

References 52 publications

(66 reference statements)

Supporting

Mentioning

464

Contrasting

Unclassified

Order By: Relevance

“…It was implied that TaHSC70 might be regulated by a pathogeninduced signaling pathway. To date, a variety of signaling molecules, such as SA, ethylene (ET), jasmonic acid (JA) and ABA, have been proposed to be involved in plant defences [42,43]. In mammals, heat-induced HSP70s can be increased through prior treatment with moderate doses of SA [44,45].…”

Section: Discussionmentioning

confidence: 99%

Characterization of a wheat HSP70 gene and its expression in response to stripe rust infection and abiotic stresses

et al. 2010

View full text Add to dashboard Cite

Members of the family of 70-kD heat shock proteins (HSP70 s) play various stress-protective roles in plants. In this study, a wheat HSP70 gene was isolated from a suppression subtractive hybridization (SSH) cDNA library of wheat leaves infected by Puccinia striiformis f. sp. tritici. The gene, that was designated as TaHSC70, was predicted to encode a protein of 690 amino acids, with a molecular mass of 73.54 KDa and a pI of 5.01. Further analysis revealed the presence of a conserved signature that is characteristic for HSP70s and phylogenetic analysis demonstrated that TaHSC70 is a homolog of chloroplast HSP70s. TaHSC70 mRNA was present in leaves of both green and etiolated wheat seedlings and in stems and roots. The transcript level in roots was approximately threefold less than in leaves but light-dark treatment did not charge TaHSC70 expression. Following heat shock of wheat seedlings at 40°C, TaHSC70 expression increased in leaves of etiolated seedlings but remained stable at the same level in green seedlings. In addition, TaHSC70 was differentially expressed during an incompatible and compatible interaction with wheat-stripe rust, and there was a transient increase in expression upon treatment with methyl jasmonate (MeJA) treatment. Salicylic acid (SA), ethylene (ET) and abscisic acid (ABA) treatments had no influence on TaHSC70 expression. These results suggest that TaHSC70 plays a role in stress-related responses, and in defense responses elicited by infection with stripe rust fungus and does so via a JA-dependent signal transduction pathway.

show abstract

Section: Discussionmentioning

confidence: 99%

Characterization of a wheat HSP70 gene and its expression in response to stripe rust infection and abiotic stresses

et al. 2010

View full text Add to dashboard Cite

show abstract

“…Experiments with Arabidopsis mutants in the ABA signaling gene ABI2 (ABSCISIC ACID INSENSITIVE 2) provided evidence that ABA can repress bacterial induction of callose [14]. Both ABI1 and ABI2 encode structurally related homologues of protein phosphatase 2C (PP2C) that act as negative regulators in the ABA response [15].…”

Section: How Do Plants Resist Pathogens?mentioning

confidence: 99%

“…Both ABI1 and ABI2 encode structurally related homologues of protein phosphatase 2C (PP2C) that act as negative regulators in the ABA response [15]. Consequently, loss-of-function mutations in ABI1 and ABI2 induce hyperresponsiveness to ABA, whereas dominant gain-of-function mutations, such as abi1-1 and abi2-2, cause ABA insensitivity [14][15][16]. ABA hyper-responsive abi2 mutants deposit less callose upon infection with P. syringae, whereas ABA-insensitive abi2-1 mutants deposit augmented levels of callose [14].…”

Section: How Do Plants Resist Pathogens?mentioning

confidence: 99%

The multifaceted role of ABA in disease resistance

Ton

Flors

Mauch‐Mani

2009

Trends in Plant Science

746

583

View full text Add to dashboard Cite

“…Remarkably, there is evidence for shared elements in the signaling pathways in the hypersensitive response to pathogens and those in response to drought or saline exposure (de Torres-Zabala et al, 2007;Mur et al, 2006;Pandey et al, 2004). A predictive understanding of these systems in the models and crops is probably still some way off, but has the potential to be extremely useful for risk assessment efforts concerning the stress responses of crop relatives in natural settings.…”

Section: Evaluating the Potential For Ecological Releasementioning

confidence: 99%

Fitness and beyond: Preparing for the arrival of GM crops with ecologically important novel characters

Wilkinson

Tepfer

2009

Environ. Biosafety Res.

View full text Add to dashboard Cite

The seemingly inexorable expansion of global human population size, significant increases in the use of biofuel crops and the growing pressures of multifunctional land-use have intensified the need to improve crop productivity. The widespread cultivation of high-yielding genetically modified (GM) crops could help to address these problems, although in doing so, steps must also be taken to ensure that any gene flow from these crops to wild or weedy recipients does not cause significant ecological harm. It is partly for this reason that new GM cultivars are invariably subjected to strict regulatory evaluation in order to assess the risks that each may pose to the environment. Regulatory bodies vary in their approach to decision-making, although all require access to large quantities of detailed information. Such an exhaustive case-by-case approach has been made tractable by the comparative simplicity of the portfolio of GM crops currently on the market, with four crops and two classes of traits accounting for almost all of the area under cultivation of GM crops. This simplified situation will change shortly, and will seriously complicate and potentially slow the evaluation process. Nowhere will the increased diversity of GM crops cause more difficulty to regulators than in those cases where there is a need to assess whether the transgene(s) will enhance fitness in a non-transgenic relative and thereafter cause ecological harm. Current practice to test this risk hypothesis focuses on attempting to detect increased fitness in the recipient. In this paper we explore the merits and shortcomings of this strategy, and investigate the scope for developing new approaches to streamline decision-making processes for transgenes that could cause unwanted ecological change.Keywords: environmental risk assessment / fitness / fitness parameters / GM crops / invasiveness / weediness THE CONTEXT OF ENVIRONMENTAL RISK ASSESSMENTThroughout the world, wherever transgenic crops are grown outside the confines of the laboratory, there is a regulatory system for governing and monitoring the conditions under which experimental field trials and/or commercial cultivation is sanctioned. There is considerable variation between individual countries in the legislative frameworks that dictate how decisions to permit, delay or halt the release of a particular transgenic event are made (Capalbo et al., 2003;Cardwell and Kerr, 2008;Guehlstorf and Hallstrom, 2005; Jepson et al., 2005;Kalaitzandonakes et al., 2007;Nasiruddin and Nasim, 2007;Ramjoue, 2007;Salleh, 2006;Zafar, 2007). Nevertheless, there appears to be a growing harmonization of the underlying process that governs decision-making, * Corresponding author: jjw@aber.ac.uk with all systems adopting a case-by-case approach in which large bodies of evidence are first presented and then evaluated in a reiterative fashion.The documents made in support of individual submissions are usually rather weighty and data-rich; they invariably include substantial information relating to the biology and agr...

show abstract

Pseudomonas syringae pv. tomato hijacks the Arabidopsis abscisic acid signalling pathway to cause disease

Cited by 491 publications

References 52 publications

Characterization of a wheat HSP70 gene and its expression in response to stripe rust infection and abiotic stresses

Characterization of a wheat HSP70 gene and its expression in response to stripe rust infection and abiotic stresses

The multifaceted role of ABA in disease resistance

Fitness and beyond: Preparing for the arrival of GM crops with ecologically important novel characters

Contact Info

Product

Resources

About