1996
DOI: 10.1016/0021-9150(96)05835-2
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PSK protects macrophages from lipoperoxide accumulation and foam cell formation caused by oxidatively modified low-density lipoprotein

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Cited by 20 publications
(9 citation statements)
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“…It is shown that PSK expresses the mimetic activity of superoxide dismutase (SOD) and promotes oxidative stress relief for cancer-bearing hosts [137,138]. PSK protects macrophages from lipoperoxide accumulation and foam cell formation caused by oxidatively modified low-density lipoprotein [139]. PSP is also considered as a good antioxidant as it exhibits strong scavenging effects on superoxide and hydroxyl radicals [140].…”
Section: Antioxidant and Free Radical Scavenging Activitiesmentioning
confidence: 99%
“…It is shown that PSK expresses the mimetic activity of superoxide dismutase (SOD) and promotes oxidative stress relief for cancer-bearing hosts [137,138]. PSK protects macrophages from lipoperoxide accumulation and foam cell formation caused by oxidatively modified low-density lipoprotein [139]. PSP is also considered as a good antioxidant as it exhibits strong scavenging effects on superoxide and hydroxyl radicals [140].…”
Section: Antioxidant and Free Radical Scavenging Activitiesmentioning
confidence: 99%
“…Protein-bound polysaccharide (Polysaccharide K, PSK) and polysaccharopeptide (PSP) from T. versicolor (Maeda et al, 1974;Chihara, 1990Chihara, , 1992Kim et al, 1999;Sia and Candlish, 1999;Fisher and Yang, 2002) are among the most studied. Their action, tested mostly in animal and in vitro models, seems to lie in a stimulation of the host immune response through the activation of lymphocyte cells in addition to a direct control of the peroxidative events and the radical cascade (Yuan et al, 1996;Slamenova et al, 2003).…”
Section: Introductionmentioning
confidence: 99%
“…PSK further repressed the mimetic activity of superoxide dismutase (SOD) and promoted oxidative stress relief for cancer-bearing hosts (Kobayashi and Kariya, 1994). PSK also gave protection to macrophages from lipoperoxide accumulation and foam cell formation created by oxidatively modified low-density lipoprotein (Yuan and Meiz, 1996). This protection is believed to be due to the induction of gene expression of antioxidative enzymes (Chen and Zhou,1997).…”
Section: Antioxidant Anti-inflammatory Free Radical Scavenging Actmentioning
confidence: 99%