Pt NPs catalyzed chemiluminescence method for Hg²⁺ detection based on a flow injection system

Abstract

Establishing a simple and accurate method for Hg2+ detection is of great importance for the environment and human health. In this work, platinum nanoparticles (Pt NPs) with different capped agents and morphologies were synthesized. It was found that Pt NPs exhibited peroxidase‐like activity that can catalyze the chemiluminescence (CL) of the luminol system without H2O2. The most intensive CL signals were obtained by using PVP‐capped Pt NPs as catalysis. Based on the fact that Hg2+ could further enhance the CL intensity in the Pt NPs‐luminol CL system, a Pt NPs‐catalyzed CL method based on a flow injection system is developed for the sensitive analysis of Hg2+. When the concentration of Hg2+ in the system increases, the CL intensity would together increase, thereby achieving sensitive Hg2+ detection. The limit of detection (LOD) was calculated to be 8.6 nM. This developed method provides a simple and rapid approach for the sensitive detection of Hg2+ and shows great promise for applications in other complex systems.

Nanozymes—Hitting the Biosensing “Target”

“…They took advantage of this catalysis mechanism and applied it toward Hg 2+ detection, as the Hg 2+ could further enhance the CL intensity in the Pt NPs-luminol CL system. With this approach, they were able to detect Hg 2+ and achieved a low-end detection limit of 8.6 nM compared with other methods (LOD ranges from 3.3 nM to 338 nM) ( Figure 8 b) [ 135 ]. Based on the intrinsic properties of Au and Pt, Wang and colleagues designed an Au@AgPt NP with surface-enhanced Raman scattering (SERS)—an active peroxidase-like activity that could be used to detect the signal molecules (which generate SERS or colorimetric signal) [ 136 ].…”

A novel colorimetric chemosensor for selective and highly sensitive determination of thiourea: An approach toward a molecular keypad lock

“…There are many conventional analytical techniques for detection and analysis of Hg 2+ and TU, for example, atomic absorption spectrometry, [ 23,24 ] inductively coupled plasma atomic emission spectrometry, [ 25,26 ] chemiluminescence, [ 27 ] cold vapor atomic absorption spectrometry, [ 28–30 ] fluorescence detection, [ 31 ] supramolecular polymer networks [ 32,33 ] for Hg 2+ analysis, and UV–VIS, [ 34–36 ] mass spectrometry, [ 37,38 ] Fourier‐transform infrared spectroscopy, [ 39 ] Raman spectroscopy, [ 40 ] high‐performance liquid chromatography, [ 41 ] and electrochemical methods [ 42–45 ] for TU measurements. All of the methods described above for analysis of two species have some shortcomings, for example, they need time‐consuming pretreatments, sophisticated operations, complicated detection processes, and relatively expensive instruments.…”

Nanomaterials for light-mediated therapeutics in deep tissue

“…Silver and platinum nanoparticles also enhance the luminol-H 2 O 2 reaction, with a similar catalytic mechanism to Au NPs. 31,32 It was also found that the catalytic activity of silver nanoparticles (AgNPs) increased with the aggregation of small Ag NPs, due to the increase in the electron density in the Ag NPs' conduction bands. 33 Other than gold, silver and platinum, copper(II) compounds like CuFe 2 O 4 nanospheres could also act as efficient catalysts for luminol-based chemiluminescence reactions.…”