Pulmonary sequestration associated with aspergillosis

Abstract

Pulmonary sequestration involves an abnormal pulmonary tissue separated from the normal pulmonary parenchyma, not connected to the tracheobronchial tree and supplied by a systemic artery. A case of intralobar pulmonary sequestration is presented. Case; a 49-year-old male was admitted to our hospital complaining of fever, cough and sputum production. Sputum culture resulted in a large growth of Aspergillus niger. Angiography showed an abnormal blood supply from the abdominal aorta to the right lower lobe. Right lower lobectomy was performed. The postoperative courses are uneventful.

Pulmonary sequestration and aspergillosis

“…PS aspergillosis is in fact essentially discovered after surgery. However, it may be suspected by preoperative positive precipitins as in our fourth patient [7,9,12,15,17], by positive sputum [17] or by CT guided biopsy [11,15,19]. In one case [7] diagnosis was provided only by precipitin positivity.…”

“…Some are exceptionnal as those due to Blastomycosis dermatitidis [3] or to Exophiala [4]. Superimposed infection by Aspergillus was reported as of 1964 [5]; To our knowledge only 14 other cases have been reported (Table 1) [6][7][8][9][10][11][12][13][14][15][16][17][18][19]; all were case reports. All cases but one were observed in adults [7] and 2/3 occured in females.…”

“…In two patients it was obtained by PS culture [13,14]; In all other patients Aspergilloma or Aspergillus hyphae were identified within the resected specimens as in three of our patients. Aspergillus fumigatus was present in most cases; Aspergillus niger observed in our first patient has been reported only once [17].…”