Quadruple-valve infective endocarditis caused by Abiotrophia defectiva

Planinc, Mislav; Kutleša, Marko; Baršić, Bruno; Rudež, Igor

doi:10.1093/icvts/ivx200

Cited by 10 publications

(7 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Most of them have underlying heart diseases, such as rheumatic heart disease ( 7 ), congenital heart disease ( 8 , 9 ), or a history of intravenous injection ( 10 ). Complications such as embolism and valve perforation almost appeared in all cases, and even multiple valves can be involved ( 11 ). Cases denying past medical history are rare, from children or non-elderly people.…”

Section: Discussionmentioning

confidence: 99%

Abiotrophia Defectiva as a Rare Cause of Mitral Valve Infective Endocarditis With Mesenteric Arterial Branch Pseudoaneurysm, Splenic Infarction, and Renal Infarction: A Case Report

Zhou

Gong

et al. 2022

Front. Med.

View full text Add to dashboard Cite

IntroductionAbiotrophia defectiva (A. defectiva) is a rare species leading to infective endocarditis (IE) with a poor prognosis. We describe a previously healthy patient with mitral valve infective endocarditis caused by A. defectiva.Case reportA young man was admitted with intermittent fever. Echocardiography confirmed vegetation on the mitral valve with evidence of valve perforation and severe mitral regurgitation. Three sets of blood cultures became positive for A. defectiva. As he presented with manifestations of mesenteric arterial branch pseudoaneurysm, splenic and renal infarction, mitral valve replacement, and embolization of superior mesenteric aneurysm were operated during 8 weeks' targeted antibiotic therapy.ConclusionThis case study emphasizes the importance of considering A. defectiva as a rare but important cause of IE and of performing blood culture to make its accurate diagnosis and timely anti-infective treatment. Early surgical management and active prevention of complications have been associated with a favorable prognosis.

show abstract

Section: Discussionmentioning

confidence: 99%

Abiotrophia Defectiva as a Rare Cause of Mitral Valve Infective Endocarditis With Mesenteric Arterial Branch Pseudoaneurysm, Splenic Infarction, and Renal Infarction: A Case Report

Zhou

Gong

et al. 2022

Front. Med.

View full text Add to dashboard Cite

show abstract

“…The AV is more commonly affected than other valves, consistent with our case, and AVR is indicated in 30% of cases [ 5 ]. The American Heart Association recommends treatment with penicillin or ceftriaxone and gentamycin for four to six weeks (vancomycin in penicillin-allergic patients) [ 1 - 6 ]. Early surgery is associated with better outcomes in patients with severe valvular disease and large vegetations [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

“…It is associated with a high risk of complications and mortality. NVS usually resides in the oral cavity, intestinal tract, or genitourinary tract, and can manifest as culture-negative endocarditis, osteomyelitis, or septic arthritis with a high propensity for septic emboli (30%) [1][2][3][4][5]. Here we present an unusual case of NVS subacute endocarditis of the aortic valve (AV) complicated by severe aortic regurgitation (AR) necessitating aortic valve replacement (AVR).…”

Section: Introductionmentioning

confidence: 99%

Pyridoxine-Deficient Streptococcus: An Uncommon Virulent Cause of Subacute Destructive Aortic Valve Endocarditis

Ahmad¹,

Banbury²,

Báez³

et al. 2022

Cureus

View full text Add to dashboard Cite

Nutritional variant streptococcus (NVS) or pyridoxal-dependent streptococcus is a rare but significant cause of infective endocarditis (IE), which presents as a diagnostic dilemma due to difficulty in organism isolation, and high rates of treatment failure, recurrence, and mortality. We discuss a case of a 52-year-old male who presented with chronic fatigue, cyclic fever, night sweats, and weight loss. He was treated with culturedirected antibiotics and surgical aortic valve replacement due to disease severity and risk of embolization. This case highlights the clinical significance of NVS IE, and the importance of early recognition, and immediate, often invasive therapy to improve outcomes.

show abstract

“…Abiotrophia defectiva, an NVS is an aggressive organism that can cause IE and also has a high probability of causing embolic complications and valvular destruction [3]. Abiotrophia defectiva is a part of the normal flora of the oral cavity, the urogenital and the intestinal tracts [4].…”

Section: Discussionmentioning

confidence: 99%

Abiotrophia defectiva: A Rare but Critical Cause of Infective Endocarditis

Agrawal

Prabhu

2019

Cureus

View full text Add to dashboard Cite

Infective endocarditis (IE) refers to an infection involving the endocardial surface of the heart. Most of the cases of IE are known to occur due to infection by viridans Streptococci or Staphylococci species. Abiotrophia defectiva is known to cause less than 1% of cases of IE. Though rare, this organism can cause life-threatening complications such as septic embolization, destruction of heart valves, and heart failure if not detected and treated timely. Here we discuss a case of a 44-year-old female who presented to our tertiary care centre with complaints of fever and easy fatiguability for two weeks. After further investigations, she was finally diagnosed to have IE due to Abiotrophia defectiva. Imaging demonstrated the presence of embolic and valvular complications as well. Through this case, we highlight the importance of early detection and timely management of this condition in order to decrease the occurrence of fatal complications and mortality.

show abstract

Quadruple-valve infective endocarditis caused by Abiotrophia defectiva

Cited by 10 publications

References 3 publications

Abiotrophia Defectiva as a Rare Cause of Mitral Valve Infective Endocarditis With Mesenteric Arterial Branch Pseudoaneurysm, Splenic Infarction, and Renal Infarction: A Case Report

Abiotrophia Defectiva as a Rare Cause of Mitral Valve Infective Endocarditis With Mesenteric Arterial Branch Pseudoaneurysm, Splenic Infarction, and Renal Infarction: A Case Report

Pyridoxine-Deficient Streptococcus: An Uncommon Virulent Cause of Subacute Destructive Aortic Valve Endocarditis

Abiotrophia defectiva: A Rare but Critical Cause of Infective Endocarditis

Contact Info

Product

Resources

About