Quality of life, anxiety prevalence, depression symptomatology and suicidal ideation among acne patients in Lithuania

Lukavičiūtė, Laura; Navickas, Petras; Navickas, Alvydas; Grigaitienė, Jūratė; Gancevičienė, Rūta; Zouboulis, Christos C.

doi:10.1111/jdv.14477

Cited by 45 publications

(52 citation statements)

References 26 publications

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“…The differences in the findings of various studies higlight the social, behavioral and cultural factors, differences in population characteristics and individual perception. In our study, both the CADI and the DLQI scores were in postive correlaiton with GAGS score as previous studies [14,22,27,28]. Unlike the CADI score; the DLQI score was not corralated with GAGS score among patients who have acne lesions on forehead.…”

Section: Discussionsupporting

confidence: 79%

Akne vulgaris hastalarının değerlendirilmesi için hangi yaşam kalite ölçeği kullanılmalıdır? CADI ya da DYKİ? Bir prospektif çalışma

Tatlıparmak

Aksoy

Karadağ

2019

Archives of Clinical and Experimental Medicine

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Aim: Acne vulgaris is one of the most common diseases that affects quality of life. While the Dermatology Life Quality Index (DLQI) is the most frequently used life quality index for dermatologic disorders, the Cardiff Acne Disability Index (CADI) is an acne-spesific quality of life scale. The aim of this study was to determine which scale should be more appropriate and practical to evaluate the quality of life in acne patients and to compare the differences between two scales. Methods: Acne scores of 273 patients who were admitted to the dermatology outpatient clinic between December 2015 and November 2016 were determined by the Global Acne Grading System (GAGS) (range 0 to 44). The DLQI (range 0 to 30) and CADI scores (range 0 to 20) were calculated to evaluate the effect of patients' quality of life. Results: The mean GAGS score of the patients was 20.3, and the mean of CADI score was 6.1, while the mean of DLQI was 6.0. There was a significant positive correlation between total GAGS score and CADI and DLQI (r=0.639, p<0.001). When the relationship between the distribution of acne lesions and quality of life scales was evaluated; CADI score was significantly higher in the forehead localization group than in the non-forehead localization group (p=0.012), and the CADI and DLQI scores were higher in the upper back group than the group without back localization (p=0.001and p= 0.017 respectively). Conclusion: In our study, it was observed that the DLQI and CADI scales were not superior to each other in evaluating the quality of life in patients with acne. Besides, we think that the effect of quality of life on facial acne cases can be determined more clearly with CADI scale.

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Section: Discussionsupporting

confidence: 79%

Akne vulgaris hastalarının değerlendirilmesi için hangi yaşam kalite ölçeği kullanılmalıdır? CADI ya da DYKİ? Bir prospektif çalışma

Tatlıparmak

Aksoy

Karadağ

2019

Archives of Clinical and Experimental Medicine

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“…Of all skin diseases, AV has been identified as the second leading cause of disability-adjusted life years after dermatitis (atopic, contact, and seborrheic dermatitis), causing loss of productivity for patients and caregivers that is equal to the productivity cost of skin cancer [4]. Additionally, AV puts a significant burden on healthcare services and may lead to depression and in severe cases to suicidal ideation and suicide attempts [5, 6].…”

Section: Introductionmentioning

confidence: 99%

Predictors of Acne Vulgaris among Adolescents in Kuwait

AlKhabbaz¹,

Al-Taiar²,

Saeed³

et al. 2019

Med Princ Pract

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Objectives: The prevalence of acne vulgaris (AV) among adolescents in Kuwait has remained mostly unknown. This study aimed to estimate the prevalence of AV and its predictors among adolescents in Kuwait. Subjects and Methods: A cross-sectional study was conducted on 714 participants who were randomly selected from public schools using multistage cluster random sampling. The presence or absence of AV, as well as severity of AV, were assessed using the Global Acne Grading Scale. Data on risk factors and potential confounders were collected from the parents through a self-administered questionnaire, and from the adolescents by face-to-face interview. Weight and height were measured in a standardized manner. Results: Of 714 participants, 320 (44.8%; 95% CI 41.1–48.6%) self-reported AV. By clinical examination, AV was found among 479 (67.1%; 95% CI 63.5–70.5%) participants. Factors that were found to be significantly associated with AV in multivariable analysis were age, gender, nationality, and BMI categories. Females compared to males (adjusted prevalence ratio [APR] 1.16 [95% CI 1.05–1.25]; p = 0.006) and overweight or obese adolescents compared to normal weight (APR 1.15 [95% CI 1.02–1.26] and 1.14 [95% CI 1.02–1.23], respectively; p = 0.026) were more likely to have AV. None of the food items studied showed an association with AV in multivariable analysis. Conclusion: The prevalence of self-reported AV seems to be lower than that reported in other settings, while the prevalence of AV by clinical examination resembles that reported in many other countries. BMI was the only modifiable risk factor associated with AV in multivariable analysis, and none of the food items studied was related to the presence or absence of AV in multivariable analysis.

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“…Adolescence represents the commonest age group prescribed ISO who are more psychologically unstable and susceptible to changes in their appearance. A European study of 255 patients with severe acne revealed that 23% had depressive symptoms (Lukaviciute, Navickas, Navickas, Ganceviciene, & Zouboulis, 2017). It has been reported that ISO does not cause depression in the general population (Ramrakha et al, 2016).…”

Section: Acne and Risk Of Depressionmentioning

confidence: 99%

Depression, isotretinoin, and folic acid: A practical review

Abdelmaksoud

Vojvodić

Ayhan

et al. 2019

Dermatologic Therapy

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Isotretinoin (ISO) is a first‐generation retinoid discovered in 1952 and approved by the FDA for the treatment of nodulocystic acne in 1982. The anti‐inflammatory properties of ISO have found its use in disorders other than acne. ISO can create psychiatric problems, including depression and suicidal ideation. These neuropsychiatric problems are very similar to disorders secondary to hyperhomocysteinemia (HHcy), vitamin B12, and folic acid (vitamin B9) deficiencies. Given that previous literature suggested folate supplementation improved the efficacy of traditional antidepressant medications, clinicians may wish to consider folate supplementation for patients with depression or possible depressive symptoms, such as acne patients with genetic susceptibility. Brain‐derived neurotrophic factor may be a cytokine‐specific screening biomarker in immune‐based antidepressive therapy.

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Quality of life, anxiety prevalence, depression symptomatology and suicidal ideation among acne patients in Lithuania

Cited by 45 publications

References 26 publications

Akne vulgaris hastalarının değerlendirilmesi için hangi yaşam kalite ölçeği kullanılmalıdır? CADI ya da DYKİ? Bir prospektif çalışma

Akne vulgaris hastalarının değerlendirilmesi için hangi yaşam kalite ölçeği kullanılmalıdır? CADI ya da DYKİ? Bir prospektif çalışma

Predictors of Acne Vulgaris among Adolescents in Kuwait

Depression, isotretinoin, and folic acid: A practical review

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