Quality of Life, Depression, and Psychosocial Characteristics of Patients Awaiting Liver Transplants

Santos, Giovani Gn; Gonçalves, Lauro C.S.; Buzzo, N.; Mendes, Thatiane Aparecida; Dias, Tábata Pereira; Silva, R.C.M.A. da; Silva, R.F. da; Felício, Helen Catharine Camarero de; Junior, Ribeiro; Miyazaki, Maria Cristina de Oliveira Santos

doi:10.1016/j.transproceed.2012.07.046

Cited by 28 publications

(27 citation statements)

References 12 publications

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“…Patients regaining professional activities after only one year had a better QoL on the long term with less emotional problems [1,3,8,10,28] . A possible bias could be that only patients in good general condition will resume Ref.…”

Section: Socio-demographic Factorsmentioning

confidence: 96%

“…The transplantation and stay at intensive care unit have been considered as traumatic stressors that diminish QoL and can cause overall mental distress. These patients are prone to some psychiatric disorders (e.g., anxiety and affective disorders, posttraumatic stress disorder) and a low QoL after LT [21,[24][25][26][27][28][29][30][31] . The short form-36 questionnaire (SF-36) is extensively used to assess the health-related QoL, which is a reliable and standardized tool comparing as well the mental [the mental component summary score (MCS)] as the physical [physical component summary score (PCS)] aspects of QoL.…”

Section: Components Of Qolmentioning

confidence: 99%

“…Relational status however, does impact QoL. Married patients have a better QoL after liver transplantation than single or non-married patients [8,19,28] . This might be explained by a better social support.…”

Section: Socio-demographic Factorsmentioning

confidence: 99%

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Quality of life after liver transplantation: State of the art

Onghena¹,

Develtere²,

Poppe³

et al. 2016

WJH

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Quality of life (QoL) after deceased donor liver transplantation is increasingly recognized as a major outcome parameter. We reviewed recent publications in this rapidly evolving field in order to summarize recent achievements in the field and to define opportunities and perspectives for research and improvement of patient care. QoL does improve after liver transplantation according to a typical pattern. During the first year, there is a significant improvement in QoL. After one year, the improvement does stabilise and tends to decline slightly. In addition to the physical condition, different psychological parameters (such as depression, anxiety, sexual function) and sociodemographic elements (professional state, sex, marital state) seem to impact QoL. Opportunities for further research are the use of dedicated questionnaires and identification of influencing factors for QoL. Core tip: Quality of life (QoL) after deceased donor liver transplantation (LT) is increasingly recognized as a major outcome parameter. This review summarizes a broad spectrum of factors that influence QoL in LT and elucidates the evolution in time of physical and mental QoL after LT. Furthermore attention is given to areas for further investigation and the use of self-report QoL questionnaires in LT. This way, we want to offer a recent and complete overview in this rapidly evolving field.

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Section: Socio-demographic Factorsmentioning

confidence: 96%

Section: Components Of Qolmentioning

confidence: 99%

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Quality of life after liver transplantation: State of the art

Onghena¹,

Develtere²,

Poppe³

et al. 2016

WJH

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“…Incorrectly diagnosing cirrhotic patients with irreversible renal failure leads to needlessly listing these patients for SLK. On an individual level, this translates to increased time on the transplant waitlist and its associated stress, anxiety, and relative negative quality of life (24)(25)(26). On a societal level, this means that fewer kidneys are available to ESRD patients, who face a 6% annual mortality on the kidney transplant waitlist (27).…”

Section: Discussionmentioning

confidence: 99%

Renal recovery following orthotopic liver transplant after prolonged kidney injury: Perspectives on diagnosing hepatorenal syndrome and determining which patients should undergo simultaneous liver kidney transplantation

Card

Moeckel

Turner

2017

jrenhep

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We present a case of an individual with cirrhosis and renal failure. This case is notable because the patient was found to have hepatorenal syndrome (HRS) superimposed on Immunoglobulin A (IgA) nephropathy. After 8 months of dialysis, the patient had significant renal recovery following orthotopic liver transplant (OLT). Cases such as this are not likely to be rare, as case series have shown that IgA deposits are a common occurrence in patients with cirrhosis, including those who have HRS. While current diagnostic criteria for HRS emphasize the importance of excluding glomerular lesions, we argue that this approach should be reconsidered. More specifically, we feel that the diagnostic approach to HRS should be more inclusive of cases in which patients have simultaneous HRS and glomerular injury. In addition, our case highlights the challenges in determining which patients will benefit most from simultaneous liver-kidney transplants over OLTs alone.

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“…[9][10][11] However, survival and life-threatening complications are not the only issues to both physicians and patients. Many patients with ESLD face serious restrictions in their health-related quality of life, 12,13 with mental disorders, such as anxiety and depression, also occurring after these procedures. 14 Another important impairment of patients with ESLD is the presence of fatigue.…”

Section: Introductionmentioning

confidence: 99%

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Benzing

Krenzien²,

Krezdorn³

et al. 2017

Exp Clin Transplant

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Objectives: To date, fatigue is still poorly understood in recipients of orthotopic liver transplant and simultaneous/sequential liver and kidney transplant procedures. The present study examined the appearance of fatigue in patients who received orthotopic liver and sequential liver and kidney transplant procedures compared with the general population and the influence of various clinical and socioeconomic factors on fatigue levels. Materials and Methods: The Multidimensional Fatigue Inventory survey was sent to all patients with a history of orthotopic liver and simultaneous/sequential liver and kidney transplant. The results were compared to data from a reference population. Results: Our survey included 276 eligible patients: 256 recipients (92.7%) of orthotopic liver transplant and 20 recipients (7.3%) of simultaneous/sequential liver and kidney transplant. Significantly lower fatigue scores were found in the general population compared with both transplant groups (P < .001). There were also no significant differences between the transplant groups. Among the clinical and socioeconomic factors, history of hepatocellular carcinoma, chronic kidney disease, age, family status, and education had a significant impact on fatigue levels. Conclusions: This is the first study to compare fatigue in recipients of orthotopic liver and simultaneous/-sequential liver and kidney transplant. We found that fatigue is an important but still poorly understood outcome after transplant.

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Quality of Life, Depression, and Psychosocial Characteristics of Patients Awaiting Liver Transplants

Cited by 28 publications

References 12 publications

Quality of life after liver transplantation: State of the art

Quality of life after liver transplantation: State of the art

Renal recovery following orthotopic liver transplant after prolonged kidney injury: Perspectives on diagnosing hepatorenal syndrome and determining which patients should undergo simultaneous liver kidney transplantation

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