Quality of Life Perception in Patients With Intractable Epilepsy or Pseudoseizures

Breier, Joshua I.; Fuchs, Kathleen L.; Brookshire, Bonnie L.; Wheless, James W.; Thomas, A. B.; Constantinou, Jules E.C.; Willmore, L. James

doi:10.1001/archneur.55.5.660

Cited by 68 publications

(39 citation statements)

References 18 publications

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“…5,7 Breier et al compared self-reported quality of life in patients with intractable epilepsy and pseudo seizures. 8 Bengali QOLIE-9, which is a valid and reliable instrument to assess the quality of life in patients suffering from epilepsy, was used to for this purpose. The Bengali translated version of QOLIE-9 is a valid and reliable instrument in the local context.…”

Section: Discussionmentioning

confidence: 99%

Quality of life in epilepsy

Singh¹,

Pandey

2017

Int J Res Med Sci

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Background: The quality of life (QOL) evaluation is a relatively new measure to evaluate the outcome of epilepsy. Many factors influence the quality of life of people with epilepsy, including seizure severity, stigma, fear, and the presence of cognitive or psychiatric problems. QOL is influenced by biological factors as well as cultural, social and religious beliefs and values. This study was planned to find out the impact of epilepsy on quality of life of epileptic patients.Methods: The study was conducted in the epilepsy clinic of department of neurology at a tertiary care hospital over a period of one year.101 patients were included after fulfilling the inclusion criteria. All the patients seeking treatment in the OPD were screened, assessed and then all procedures were fully explained to them. History regarding name, age sex, socio-demographic profile and detailed history regarding seizure disorder was taken from both the patient and the reliable informant. Bengali version of QOLIE-9 was used to assess the quality of life.Results: One hundred and one patients with epilepsy consisting of 70 men (69.3%) and 31 women (30.7%) were included. Their ages ranged from 15 to 52, the mean age being 26.17 (SD = 7.84). Out of the 101 patients, 65 patients (64.4%) were suffering from partial epilepsies and 36 patients (35.6%) were suffering from generalized epilepsies. Mean QOLIE-9 total scores were 16.66, 19.74, 20.13 and 24.00 in married, widows, unmarried and separated individuals respectively. The differences in the means were statistically significant on ANOVA (p value 0.002). Mean QOLIE-9 total scores were 27.75, 19.64, 19.65, 18.14 and 18.00 in primary, secondary, higher secondary, graduate and postgraduate individuals respectively. The differences were highly significant statistically on ANOVA (p value<0.001). Frequency of seizures per month was positively correlated with QOLIE-9 total scores (Pearson Correlation 0.622) and was highly statistically significant (p value<0.001).Conclusions: Frequent seizures, lower education level and single status are associated with lower quality of life in persons with epilepsy.

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Section: Discussionmentioning

confidence: 99%

Quality of life in epilepsy

Singh¹,

Pandey

2017

Int J Res Med Sci

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“…At a follow-up after about two years, 56% of individuals so afflicted reported poor or very poor physical, mental and social well-being, with the outcome being worse for those who had a long history of seizures and concomitant psychiatric pathology (Lempert & Schmidt, 1990). In another study, Breier et al (1998) found that PNES patients reported a general low level of quality of life and experienced more physical limitations than chronic complex partial seizure patients.…”

Section: General Psychopathologymentioning

confidence: 99%

Demographic and Seizure Variables, But Not Hypnotizability or Dissociation, Differentiated Psychogenic from Organic Seizures

Litwin¹,

Cardeña²

2001

Journal of Trauma & Dissociation

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ABSTRACT. Early detection and differential diagnosis of psychogenic non-epileptic seizures (PNES) and epileptic seizures (ES) is a major clinical issue in comprehensive epilepsy centers. Using blind conditions with patients with PNES (N = 10) and ES (N = 31) before diagnosis, we tested the hypotheses that individuals with PNES would exhibit significantly greater dissociativity, hypnotizability, absorption, and history of early abuse than ES patients. Although PNES patients tended to show greater dissociative phenomena, only the last of our hypotheses was fully supported. Although absorption did not discriminate between the two diagnostic groups, it was significantly higher among those reporting early abuse. A logistic regression analysis using scores on dissociation, hypnotizability and absorption showed them to be poor predictors of diagnosis; however, other analyses revealed that female gender, reports of multiple trauma incidents lasting months or years, initial seizure onset in late teens or twenties, and daily seizure attacks significantly differentiated PNES from ES patients. Thus, demographic and seizure variables proved to be much better predictors of diagnosis Richard Litwin is in Private Practice, Cleveland, OH.

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“…Consequently social isolation is very common in PWE [2]. Increased feelings of anxiety and depression can be further compounded by reduced social opportunities, lack of social support, poor self-esteem, a reduced sense of mastery, stigma and discrimination, an overprotective parental style in childhood or vocational disability [35,[52][53][54][63][64][65][66][67][68][69][70]. Self-esteem and sense of mastery have been inversely related to higher scores on measures of depression and anxiety in PWE [71].…”

Section: Psychological Factors: Anxiety and Depressionmentioning

confidence: 99%

“…Individuals may not know when a seizure will occur and often have difficulty accepting living with a chronic condition that may or may not improve. This can cause PWE to feel that they lack control over their life, can lower mood and heighten feelings of anxiety [6,[52][53][54]. This has been reflected in research where PWE demonstrate a lower sense of mastery in relation to healthy controls [55].…”

Section: Dispositional Factors: Self-esteem and Sense Of Masterymentioning

confidence: 99%

Quality of Life Issues in Epilepsy

McCagh¹

2014

Epilepsy Topics

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Quality of Life Perception in Patients With Intractable Epilepsy or Pseudoseizures

Cited by 68 publications

References 18 publications

Quality of life in epilepsy

Quality of life in epilepsy

Demographic and Seizure Variables, But Not Hypnotizability or Dissociation, Differentiated Psychogenic from Organic Seizures

Quality of Life Issues in Epilepsy

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