Quantification of monomer elution and carbon–carbon double bonds in dental adhesive systems using HPLC and micro-Raman spectroscopy

Miletić, Vesna; Santini, Ario; Trkulja, Ivan

doi:10.1016/j.jdent.2008.11.006

Cited by 56 publications

(45 citation statements)

References 35 publications

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“…This in vitro elution experiment could demonstrate the presence of these four monomers, together with CQ and the different forms of BisEMA (i.e., BisEMA‐3 and BisEMA‐10). These results are in accordance with previous studies . Venus Pearl is based on TCD‐DI‐HEA and UDMA.…”

Section: Resultssupporting

confidence: 93%

Simultaneous analysis of bisphenol A based compounds and other monomers leaching from resin-based dental materials by UHPLC-MS/MS

et al. 2017

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Resin-based dental materials have raised debates concerning their safety and biocompatibility, resulting in a growing necessity of profound knowledge on the quantity of released compounds into the oral cavity. In this context, the aim of this study was to develop a comprehensive and reliable procedure based on liquid chromatography with mass spectrometry for the simultaneous analysis of various leached compounds (including bisphenol A based compounds) in samples from in vitro experiments. Different experiments were performed to determine the optimal analytical parameters, comprising mass spectrometry parameters, chromatographic separation conditions, and sample preparation. Four internal standards were used as follows: deuterated diethyl phthalate and bisphenol A (commercially available), and deuterated analogues of triethylene glycol dimethacrylate and urethane dimethacrylate (custom-made). The optimized method was validated for linearity of the calibration curves and the associated correlation coefficient, lower limit of quantification, higher limit of quantification, and intra- and interassay accuracy and precision. Additionally, the developed liquid chromatography with tandem mass spectrometry method was applied to the analysis of leaching compounds from four resin-based dental materials. The results indicated that this method is suitable for the analysis of different target compounds leaching from dental materials. This method might serve as a valuable basis for quick and accurate quantification of leached compounds from resin-based dental materials in biological samples.

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Section: Resultssupporting

confidence: 93%

Simultaneous analysis of bisphenol A based compounds and other monomers leaching from resin-based dental materials by UHPLC-MS/MS

et al. 2017

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“…On the other hand, the residual monomers present at 7 d may well have been leached to the medium, decreasing the number of carbon double bonds and not increasing stiffness of the restoration. That means the increase in the degree of conversion was possibly apparent with the residual monomer eluted after 4 m. 42 In this regard, one could say that at 7 d the reaction is still occurring, thus explaining the low initial values of the selfetch groups (Table 2). However, the monomer elution rationale is more likely, because the degree of conversion increase was not accompanied by bond strength improvements.…”

Section: Discussionmentioning

confidence: 96%

Bond strengths, degree of conversion of the cement and molecular structure of the adhesive–dentine joint in fibre post restorations

Melo

Bottino

Galvão³

et al. 2012

Journal of Dentistry

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“…The results showed that AgBr/NPVP-modified PMMA resins were non-cytotoxic towards HDPCs according to the standard. It is well accepted that polymerization of dental resinous materials is never complete 38, 39 and the unpolymerized monomers can be released over time. The unpolymerized monomers can be the primary reason for the cytotoxicity of dental resinous materials 40 .…”

Section: Discussionmentioning

confidence: 99%

The antifungal effects and mechanical properties of silver bromide/cationic polymer nano-composite-modified Poly-methyl methacrylate-based dental resin

Zhang

Chen

Huang

et al. 2017

Sci Rep

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Poly-methyl methacrylate (PMMA)-based dental resins with strong and long-lasting antifungal properties are critical for the prevention of denture stomatitis. This study evaluated the antifungal effects on Candida albicans ATCC90028, the cytotoxicity toward human dental pulp cells (HDPCs), and the mechanical properties of a silver bromide/cationic polymer nano-composite (AgBr/NPVP)-modified PMMA-based dental resin. AgBr/NPVP was added to the PMMA resin at 0.1, 0.2, and 0.3 wt%, and PMMA resin without AgBr/NPVP served as the control. Fungal growth was inhibited on the AgBr/NPVP-modified PMMA resin compared to the control (P < 0.05), and the antifungal activity increased as the incorporation of the AgBr/NPVP antimicrobial composite increased. Confocal laser scanning microscopy (CLSM) showed that the number of fungal cells attached to the modified PMMA resin was considerably lower than in the control. The relative growth rate of HDPCs of modified groups were higher than 75%. The flexural strength (FS) and flexural modulus (FM) were not significantly different (P > 0.05) between the experimental and control groups. These data indicate that the incorporation of AgBr/NPVP conferred strong and long-lasting antifungal effects against Candida albicans to the PMMA resin, and it has low toxicity toward HDPCs, and its mechanical properties were not significantly affected.

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Quantification of monomer elution and carbon–carbon double bonds in dental adhesive systems using HPLC and micro-Raman spectroscopy

Cited by 56 publications

References 35 publications

Simultaneous analysis of bisphenol A based compounds and other monomers leaching from resin-based dental materials by UHPLC-MS/MS

Simultaneous analysis of bisphenol A based compounds and other monomers leaching from resin-based dental materials by UHPLC-MS/MS

Bond strengths, degree of conversion of the cement and molecular structure of the adhesive–dentine joint in fibre post restorations

The antifungal effects and mechanical properties of silver bromide/cationic polymer nano-composite-modified Poly-methyl methacrylate-based dental resin

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