Quantile regression methods for left-truncated and right-censored data

Cheng, Jung-Yu; Huang, Shu-Chun; Tzeng, Shinn-Jia

doi:10.1080/00949655.2015.1016433

Cited by 6 publications

(1 citation statement)

References 20 publications

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“…More broadly speaking, we are aware that the emergence of other censoring types, such as interval censored data, current status data, and left truncated data, has prompted the extension of quantile regression. See, for example, the extended quantile regression work of Zhou et al , 37 Kim et al , 38 and Lin et al 39 for interval censored outcome data, of Ou et al 40 for current status data, and of Cheng et al 41 and Shen 42 for left truncated data.…”

Section: Discussion and Future Directionsmentioning

confidence: 99%

Quantile regression for survival data in modern cancer research: expanding statistical tools for precision medicine

Hong

Christiani

2019

Precision Clinical Medicine

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Quantile regression links the whole distribution of an outcome to the covariates of interest and has become an important alternative to commonly used regression models. However, the presence of censored data such as survival time, often the main endpoint in cancer studies, has hampered the use of quantile regression techniques because of the incompleteness of data. With the advent of the precision medicine era and availability of high throughput data, quantile regression with high-dimensional predictors has attracted much attention and provided added insight compared to traditional regression approaches. This paper provides a practical guide for using quantile regression for right censored outcome data with covariates of low- or high-dimensionality. We frame our discussion using a dataset from the Boston Lung Cancer Survivor Cohort, a hospital-based prospective cohort study, with the goals of broadening the scope of cancer research, maximizing the utility of collected data, and offering useful statistical alternatives. We use quantile regression to identify clinical and molecular predictors, for example CpG methylation sites, associated with high-risk lung cancer patients, for example those with short survival.

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