Quassinoids from Aeschrion crenata

Five New Quassinoids from the Bark of Picrasma quassioides

“…2,b). Correlations between HÀC(9) and HOÀC (11), between HÀC(9) and H a ÀC (15), and between H a ÀC(15) and Me(21) were observed, indicating that the HOÀC(11) and HOÀC(13) groups were a-and b-configured, respectively. The NOESY data were consistent with a 3D structure generated by computer modeling (Fig.…”

“…Picraqualide E (5), a white amorphous powder, was established to have the molecular formula C 25 (16) and C (15), and between HOÀC(16) and C (16) (Fig. 3,a), although the key HMBC correlations between HÀC(7) and C(16), or between HÀC(16) and C (7), were not observed.…”

“…The eleven known quassinoids also isolated from P. quassioides were identified as nigakilactone E (6) [12], nigakilactone F (7) [12], kusulactone (8) [13], javanicin U (9) [9c], 12-norquassin (10) [15], quassin (11) [16], 2,3-didehydropicrasin B (12) [17], nigakilactone B (13) [12], nigakilactone C (14) [12], picrasin B (15) [14b], and simalikalacton C (16) [18] on the basis of their 1 H-and 13 C-NMR data as well as HR-EI mass-spectral data. The complete NMR assignment of 8 was achieved by a combination of 2D-NMR techniques (see Tables 1 and 2).…”

“…The signal for HÀC(9) showed NOESY correlations with both HÀC (5) and the H-atom of HOÀC (11), suggesting that these groups were all aoriented. The a-configuration for Me(21) was established based on NOESY interactions with the equatorial H b ÀC (15). A 3D structure of compound 1, generated by MM2 computer modeling (Chem 3D Pro, Version 6.0; Cambridge Soft, Cambridge, MA, USA), is shown in Fig.…”

Alcaloides β-indolopiridoquinazolínicos de Esenbeckia grandiflora mart. (Rutaceae)

“…1 Destas, 22 espécies, incluindo E. grandiflora, tiveram sua constituição química investigada. Dentre os compostos isolados, alcaloides furoquinolínicos (E. alata, 3 E. almawillia, 2,4 E. berlandieri, 5 E. belizencis, 6 E. conspecta, 7 E. flava, 5 E. febrifuga, 8 E. hieronimi, 9 E. leiocarpa, 10 E. litoralis, 5,11 E. pentaphylla, 12 E. pilocarpoides 13 e E. yaxhoob 14 ), quinolinônicos (E. almawillia, 2,4,[15][16][17] E. belizencis, 6 E. flava, 5 E. hieronimi 9 e E. leiocarpa, 10,18,19 E. pentaphylla 12 e E. pilocarpoides 13 ) e acridônicos (E. litoralis, 5 E. pentaphylla, 12 E. pilocarpoides 13 ), derivados alquil-, pirano-e furocumarínicos (E. alata, 3,20 E. almawillia, 4 E. berlandieri, 5 E. conspecta, 7 E. flava, 5 E. febrifuga, 21 E. hieronimi, 9 E. leiocarpa, 10 E. litoralis, 5,11 E. ovata, 22 E. pentaphylla 12 e E. yaxhoob 23 ) e os limonoides (E. berlandieri, 5 E. flava, 5 E. febrifuga, 24 E. litoralis, 5 E. hartmanni, …”