Race of apparent abnormalities in neonates born in Amir-Almomenin hospital of Sistan

حسینی, سوسن; Hosseini, Seyyed Ali; روش, عباس نیک; Nikravesh, Azita; حسینی, زهره سادات; Hashemi, Z S; رخشی, ناهید; Rakhshi, N

doi:10.29252/jnkums.6.3.573

Cited by 5 publications

(3 citation statements)

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“…Khoshhal-Rahdar et al (24) and Alijahan et al (25) found musculoskeletal anomalies as the most common congenital defects. In the Hosseini et al (26) study, anomalies of eye, ear and face ranked first followed by nervous system disorders. According to Jalali et al (23), the most and the least prevalent congenital anomalies were respectively linked to musculoskeletal and genitourinary abnormalities.…”

Section: Discussionmentioning

confidence: 98%

Determining the Risk Factors of Congenital Anomalies of Newborns in Hamadan Province

et al. 2020

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Background: Congenital anomalies are considered as one of the major causes of neonatal death. The prevalent pattern of congenital anomalies may vary diachronically or geographically. With regard to the pervasiveness of under-five mortality (probability of dying between birth and exactly 5 years old) in Hamadan province in the recent years, the present study intended to determine the risk factors of congenital anomalies of newborns in Hamadan province in 2017. Methods: The present case-control study was conducted in the hospitals affiliated to Hamadan University of Medical Sciences for 6 months in 2017. The study targeted all the newborns from birth to hospital discharge. The neonatal cases with congenital anomalies were identified through clinical examination. A report sheet was assigned to a healthy newborn, as a control, per each case of congenital anomalies born on the same day and in the same hospital. Once data was collected, they were statistically analyzed by means of SPSS V. 16 software. Results: According to the current results, the prevalence of congenital anomalies was 0.85% (8.5 per 1,000 live births). Genitourinary (40%), musculoskeletal (25.2%), eye, ear and neck (18.5%), chromosomal (5.9%), respiratory tract (3.7%) and cardiovascular system (2.2%) were the most common congenital anomalies, respectively. Consanguineous marriage, concomitant use of contraceptive methods and male sex were found to be the most important risk factors for congenital anomalies. Conclusions: The present study aimed at identifying the various types and prevalence of congenital anomalies in Hamadan province. Regular prenatal examination and early diagnosis for prevention, early intervention and scheduled termination of pregnancy are recommended. Besides, public awareness of the disadvantages of consanguineous marriage and other pertaining risk factors affecting the incidence of congenital anomalies is also recommended.

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Section: Discussionmentioning

confidence: 98%

Determining the Risk Factors of Congenital Anomalies of Newborns in Hamadan Province

et al. 2020

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“…Families in low-income countries have less access to health services and are deprived of access to health care due to financial problems or lack of services [8,9]. For example, Zahari et al indicated that the prevalence of congenital heart diseases in people with DS is similar in Malaysia and high-income countries, but the survival rate was lower in this country because of the delay in performing required medical surgeries due to limited human and physical resources [10].…”

Section: Discussionmentioning

confidence: 99%

The Relationship Between Health System Functions and the Prevalence of Down Syndrome on a Global Scale

Karyani¹,

Soltani²,

Akbari³

et al. 2022

J Rehab

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Objective: Down syndrome or trisomy 21 is one of the most common human chromosomal disorders that affect cognitive functions, communication and behavioral skills. At the macro level, various factors can contribute to the Down syndrome prevalence and mortality. This study aimed to investigate the association of health system functions with Down syndrome prevalence and mortality worldwide. Materials & Methods: The study was a cross-sectional study conducted based on the secondary analysis of existing data in 2019. Data from 202 countries in six different regions (African Region [AFRO], Eastern Mediterranean Region [EMRO], European Region [EURO], South-East Asia Region [SEARO], Western Pacific Region [WPRO], and Pan American Health Organization [PAHO]) were included in the study. Data were extracted from the World Health Organization (WHO), the World Bank and the Institute for Health Metrics and Evaluation databases. The adjusted linear regression analysis was used to examine the association between health system-related factors with prevalence of, and death due to Down syndrome as the outcome variables. In the present study, two functions of health financing (domestic general government health expenditure [GGHE-D] per capita in PPP [purchasing power parity] int$, domestic private health expenditure [PHE-D] per capita in PPP int$, external health expenditure [EXT] per capita in PPP int$) and health system resources (nurse and midwifery personnel, generalist medical practitioners [GMP], specialist medical practitioners [SMP], pharmacists, dentists, physiotherapists) were included in the study as independent variables. We used the Stata software version 14 to analyze Results: Africa and low-income countries had the highest deaths due to Down syndrome. On the other side, Europe and high-income countries had the highest prevalence of Down syndrome worldwide. According to the available data, Iran had a lower prevalence (29.31 vs 38.44 per 100,000 population) and higher deaths (0.34 vs 0.32 per 100,000 population) compared to high- income countries. The 20-year trend of prevalence of, and deaths due to Down syndrome in Iran has always been lower and higher than high-income countries, respectively. Linear regression analysis showed that GGHE-D per capita (β=0.385, P<0.001) and PHE-D per capita (β=0.354, P=0.02) could predict the prevalence of Down syndrome significantly in the study countries. On the other hand, nurse and midwifery personnel (β=-0.607, P=0.014) and number of SMP (β=0.420, P=0.025) were associated with increased deaths from Down syndrome in the included countries. Conclusion: Our findings showed GGHE-D and PHE-D are associated with a higher prevalence of Down syndrome in health systems. On the other hand, health system resources (nurses and SMP) were the main predictors of death due to Down syndrome in the included countries. International organizations and governments need to monitor and improve the equitable access of vulnerable groups to health services in low-income countries. Improving health insurance coverage and equitable distribution of health resources is suggested to reduce deaths due to Down syndrome in Iran.

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“…The center for disease control and prevention also reported that around 3% of all births in the United States are affected by CAs (20). Studies in Iran also showed that the prevalence of major CAs in Tehran was 18 cases per 1000 births (6), while the prevalence of obvious major CAs per 1000 births was 8.5 -17 cases among different ethnic groups in Gorgan (9), 8.2 cases in Ardebil (10), 8.92 -2046 cases in different areas of Golestan province (21), and 18 cases in Sistan (22). The CA prevalence in an earlier study in Birjand was also as high as 5.34 cases per 1000 live births (23).…”

Section: Discussionmentioning

confidence: 99%

The Prevalence of Major Congenital Anomalies Among Live Births in Birjand, Iran

2018

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Background and Objectives: Congenital anomalies can increase the neonatal mortality rate. Infants with anomalies suffer from long-term disabilities that impose heavy burdens on their families and healthcare systems. Understanding the prevalence of congenital anomalies helps health policy-makers develop better health-related policies. This study aimed to evaluate the prevalence of major congenital anomalies among live births in Birjand city, Iran. Methods: This cross-sectional descriptive-analytical study was conducted on 6,000 infants who were born from September 23, 2015, to March 6, 2016, in the maternity departments in Birjand. Stillbirths and infants who died immediately after birth, i.e. before the assessment for anomalies, were excluded. On the first day of birth, a neonatologist or a pediatrician performed a careful physical examination for each infant to diagnose probable congenital anomalies. Appropriate diagnostic procedures were also used to confirm the diagnosis when needed. Then, data on the characteristics of infants were collected using a researcher-made checklist. The data were reported using descriptive statistics such as absolute frequency, relative frequency, mean, and standard deviation. Moreover, the Chi-square and Fisher's exact tests were conducted using the SPSS computer program (v. 16.0) for hypothesis testing at a significance level of less than 0.05. Results: The prevalence of major congenital anomalies was 1.83 cases per 1000 live births. The prevalence rates of low birth weight and prematurity were significantly greater among infants with congenital anomalies than in their non-afflicted counterparts (45.5% vs. 15.9% and 36.4% vs. 11.1%, respectively; P < 0.05). Around 63.6% of the anomalies were among male infants and 54.5% of parents had kinship relationships. Conclusions: This study showed that the prevalence of major congenital anomalies among live births in Birjand was 1.83 cases per 1000 live births, which is less than the rates reported in other areas of Iran.

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Race of apparent abnormalities in neonates born in Amir-Almomenin hospital of Sistan

Cited by 5 publications

References 0 publications

Determining the Risk Factors of Congenital Anomalies of Newborns in Hamadan Province

Determining the Risk Factors of Congenital Anomalies of Newborns in Hamadan Province

The Relationship Between Health System Functions and the Prevalence of Down Syndrome on a Global Scale

The Prevalence of Major Congenital Anomalies Among Live Births in Birjand, Iran

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