Radial Wicking of Biological Fluids in Paper

Hertaeg, Michael J.; Tabor, Rico F.; Berry, Joseph D.; Garnier, Gil

doi:10.1021/acs.langmuir.0c01318

Cited by 16 publications

(22 citation statements)

References 47 publications

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“…Using the conservative case of a 6 μ l whole blood drop on untreated glass H = 0.86 × 10 −3 m, R = 2.9 × 10 −3 m, μ = 4.0 × 10 −3 Pa s , γ = 50 × 10 −3 N m −1 and E˙=3.5×10−8 m s−1. Values of μ [48], γ [49] and E˙ [5,50] are taken from literature. This leads to a value of H4γ/3μE˙R4 of 9.2 × 10 5 demonstrating the dominance of surface tension.…”

Section: Discussionmentioning

confidence: 99%

Pattern formation in drying blood drops

Hertaeg

Tabor

Routh

2021

Phil. Trans. R. Soc. A.

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Patterns in dried droplets are commonly observed as rings left after spills of dirty water or coffee have evaporated. Patterns are also seen in dried blood droplets and the patterns have been shown to differ from patients afflicted with different medical conditions. This has been proposed as the basis for a new generation of low-cost blood diagnostics. Before these diagnostics can be widely used, the underlying mechanisms leading to pattern formation in these systems must be understood. We analyse the height profile and appearance of dispersions prepared with red blood cells (RBCs) from healthy donors. The red cell concentrations and diluent were varied and compared with simple polystyrene particle systems to identify the dominant mechanistic variables. Typically, a high concentration of non-volatile components suppresses ring formation. However, RBC suspensions display a greater volume of edge deposition when the red cell concentration is higher. This discrepancy is caused by the consolidation front halting during drying for most blood suspensions. This prevents the standard horizontal drying mechanism and leads to two clearly defined regions in final crack patterns and height profile. This article is part of a discussion meeting issue ‘A cracking approach to inventing new tough materials: fracture stranger than friction’.

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Section: Discussionmentioning

confidence: 99%

Pattern formation in drying blood drops

Hertaeg

Tabor

Routh

2021

Phil. Trans. R. Soc. A.

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“…Hertaeg et al. 2020). In addition, knowing that typical evaporation rate for water is of order m s at room temperature in the diffusion-limited regime, it takes hours for a sessile droplet of mm in thickness to evaporate (see e.g.…”

Section: Potential Implicationsmentioning

confidence: 97%

“…FisherScientific 2011; Hertaeg et al. 2020). In addition, the initial apparent contact angle (above the surface of the paper) and the advancing contact angle (within the paper) are both assumed to be 15, i.e.…”

Section: Potential Implicationsmentioning

confidence: 99%

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Growth of a fluid-infused patch from droplet drainage into a thin porous layer

Zheng

2022

J. Fluid Mech.

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Growth of a fluid-infused patch on a thin porous layer, e.g. on a piece of paper or cloth, is related to the transmission of virus particles through exhaled droplets and aerosols. We present a theoretical model to describe how a wet patch develops gradually through imbibition, once a sessile droplet attaches at a permeable surface and drains gradually into a thin porous layer. Two limiting cases are considered based on different assumptions on the motion of the contact line during the coupled process of drop drainage and patch growth: (i) the apparent contact angle remains unchanged, so the radius of a sessile droplet decreases with time; and (ii) the location of the contact line remains pinned, so the contact angle decreases as time progresses. The model leads to evolution pathways for both the droplet and the fluid film within the porous layer, without introducing arbitrary fitting parameters. Potential implications of the model and its solutions are also discussed briefly in the context of the outspread of COVID-19, employing physical parameters for exhaled droplets, paper and cloth.

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“…Furthermore, porosimetry techniques typically employ nonwetting fluids, which require high pressures to intrude porous substrates. However, in various applications, knowledge on the porous structure of a material in contact with the wetting fluid is of notable interest, particularly if materials are considered whose geometric structures change because of swelling . A prominent example of such materials is filter paper.…”

Section: Introductionmentioning

confidence: 99%

Porosity Centrifuge: Determination of Pore Sizes of Swellable Porous Materials under Hypergravity

2021

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Porous materials are ubiquitous and essential for many processes in nature as well as in industry, and the need to produce them from renewable materials will definitely increase. A prominent example for such a fully recyclable and biogenic porous material is paper, a material that contains macropores formed in between the fibers as well as a large distribution of much finer pores on and within the fiber walls. While the determination of pore sizes is of central importance for the characterization of such materials, their determination is usually only possible with complex methodologies. The determination of pore sizes in the context of water has remained largely unsolved to date, in particular, if water-swellable materials are considered. Here, we introduce a completely new way of determining pore sizes of materials even under swelling conditions. Using a centrifugal device and studying the imbibition of water into paper at various centrifugal forces that oppose the capillary forces, we can access the mean pore size of different paper materials in an experimentally simple fashion. In addition, we can show that the pore size values obtained with our "centrifugal porosimetry" are consistent with the values obtained using other methods, usually much more involved methods. For this purpose, we measure wellcharacterized translucent macroporous materials using water, ranging from simple glass capillaries to standard filters and nitrocellulose membranes.

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Radial Wicking of Biological Fluids in Paper

Cited by 16 publications

References 47 publications

Pattern formation in drying blood drops

Pattern formation in drying blood drops

Growth of a fluid-infused patch from droplet drainage into a thin porous layer

Porosity Centrifuge: Determination of Pore Sizes of Swellable Porous Materials under Hypergravity

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