Several studies have highlighted that the IEEE 802.15.4 standard presents a number of limitations such as low reliability, unbounded packet delays and no protection against interference/fading, that prevent its adoption in applications with stringent requirements in terms of reliability and latency. Recently, the IEEE has released the 802.15.4e amendment that introduces a number of enhancements/modifications to the MAC layer of the original standard in order to overcome such limitations. In this paper we provide a clear and structured overview of all the new 802.15.4e mechanisms. After a general introduction to the 802.15.4e standard, we describe the details of the main 802.15.4e MAC behavior modes, namely Time Slotted Channel Hopping (TSCH), Deterministic and Synchronous Multichannel Extension (DSME), and Low Latency Deterministic Network (LLDN). For each of them, we provide a detailed description and highlight the main features and possible application domains. Also, we survey the current literature and summarize open research issues.