Rapid and highly sensitive detection of mercury ions using a fluorescence-based paper test strip with an N-alkylaminopyrazole ligand as a receptor

Aragay, Gemma; Montón, Helena; Pons, Josefina; Font-Bardı́a, Mercè; Merkoçi, Arben

doi:10.1039/c2jm15717a

Cited by 47 publications

(36 citation statements)

References 35 publications

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“…18,19 The first paper-based sensor was reported in 1883, 20 and since that time the field has evolved from lateral flow assays (1D) 6,21-23 to 3D devices. 16,24-29 Historically, most paper-based assays are implemented using nitrocellulose, 30,31 but the characteristics of this material are best suited for lateral flow sensing rather than multidimensional sensor systems.…”

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DNA Detection Using Origami Paper Analytical Devices

et al. 2013

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We demonstrate the hybridization-induced fluorescence detection of DNA on an origami-based paper analytical device (oPAD). The paper substrate was patterned by wax printing and controlled heating to construct hydrophilic channels and hydrophobic barriers in a three-dimensional fashion. A competitive assay was developed where the analyte, a single-stranded DNA (ssDNA), and a quencher-labeled ssDNA competed for hybridization with a fluorophore-labeled ssDNA probe. Upon hybridization of the analyte with the fluorophore-labeled ssDNA, a linear response of fluorescence vs. analyte concentration was observed with an extrapolated limit of detection < 5 nM and a sensitivity relative standard deviation as low as 3%. The oPAD setup was also tested against OR/AND logic gates, proving to be successful in both detection systems.

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“…18 Nonetheless, a few groups have successfully developed paper-based sensors that utilize fluorescence detection 16,25 and yield low LODs. 23,44 …”

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DNA Detection Using Origami Paper Analytical Devices

et al. 2013

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“…Several paper monitor sensors have been recently developed for screening contaminants (Alkasir et al 2012) and toxic metals in water (Aragay et al 2012;Ratnarathorn et al 2012). Several paper monitor sensors have been recently developed for screening contaminants (Alkasir et al 2012) and toxic metals in water (Aragay et al 2012;Ratnarathorn et al 2012).…”

Section: Discussionmentioning

confidence: 99%

A new paper sensor method for field analysis of acid volatile sulfides in soils

Pellegrini

Contin

Antisari

et al. 2018

Environmental Toxicology and Chemistry

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Monitoring of biogenic sulfide is important because acid volatile sulfides (AVS) represent a reactive pool responsible for immobilization of toxic metals. We propose a new sulfide paper sensor method for semiquantitative determination of AVS in which developed color is compared to a reference chart. The method was validated against the ion‐selective microelectrode and the purge‐and‐trap methods. For fieldwork, readings should fall within 1 to 10 μmoles S2–. Considering that the volume of soil used ranged between 1 and 16 cm3, the corresponding soil sulfides concentration range spans from 0.06 to 10 mmoles S2– cm−3. The sulfide paper sensor method is highly suitable for field screening and has sensitivity levels comparable to laboratory methods. Environ Toxicol Chem 2018;37:3025–3031. © 2018 SETAC

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“…To date, water monitor sensors have been developed for detecting organophosphate and carbamate pesticides (Hossain et al, 2009a), various metals (Hossain and Brennan, 2011;Apilux et al, 2010Apilux et al, , 2012Aragay et al, 2012;Nie et al, 2010;Ratnarathorn et al, 2012), coliform bacteria and phenolic compounds (Alkasir et al, 2012). However, one area where mPAD testing technology is lacking is the existence of simple, quantitative on-site analysis methods that can be performed at low cost by untrained personnel.…”

Section: Introductionmentioning

confidence: 98%