Rapid assessment of regional and global left ventricular function using three-dimensional k-t BLAST imaging

Huber, Steffen; Muthupillai, Raja; Mojibian, Hamid; Cheong, Benjamin; Kouwenhoven, Marc; Flamm, Scott D.

doi:10.1016/j.mri.2008.01.027

Cited by 8 publications

(6 citation statements)

References 37 publications

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“…Table 2 shows that the 3D measurements have greater inter‐ and intraobserver variability than the 2D measurements except the interobserver variability for LVEDV and correspondingly LVEF. The limits of agreement and the systematic deviation for LV function measurements with our proposed technique presented in Tables 1 and 2 are comparable to the results from the literature (2, 4, 5). The differences in our LV functional measurements are therefore not clinically relevant, but further validation on a larger set of subjects is desirable.…”

Section: Resultssupporting

confidence: 87%

“…This approach is sensitive to misregistration errors between slices because of variations in breathholding positions, though it benefits from the inflow enhancement effect (1). Recent advances in accelerated acquisition strategies allow single breathhold whole heart cardiac exams with superior SNR and contrast‐to‐noise ratio (CNR) using three‐dimensional (3D) imaging research sequences (2–5). However, the limited duration of a single breathhold requires compromises in spatial resolution, temporal resolution, volume coverage, and image quality.…”

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confidence: 99%

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Single breathhold cardiac CINE imaging with multi‐echo three‐dimensional hybrid radial SSFP acquisition

Liu

Wieben

Jung

et al. 2010

Magnetic Resonance Imaging

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Purpose: To achieve single breathhold whole heart cardiac CINE imaging with improved spatial resolution and temporal resolution by using a multi-echo three-dimensional (3D) hybrid radial SSFP acquisition. Materials and Methods:Multi-echo 3D hybrid radial SSFP acquisitions were used to acquire cardiac CINE imaging within a single breathhold. An optimized interleaving scheme was developed for view ordering throughout the cardiac cycle.Results: Whole heart short axis views were acquired with a spatial resolution of 1.3 Â 1.3 Â 8.0 mm 3 and temporal resolution of 45 ms, within a single 17 s breathhold. The technique was validated on eight healthy volunteers by measuring the left ventricular volume throughout the cardiac cycle and comparing with the conventional 2D multiple breathhold technique. The left ventricle functional measurement bias of our proposed 3D technique from the conventional 2D technique: end diastolic volume À3.3 mL 6 13.7 mL, end systolic volume 1.4 mL 6 6.1 mL, and ejection fraction À1.7% 6 4.3%, with high correlations 0.94, 0.97, and 0.91, accordingly. Conclusion:A multi-echo 3D hybrid radial SSFP acquisition was developed to allow for a whole heart cardiac CINE exam in a single breathhold. Cardiac function measurements in volunteers compared favorably with the standard multiple breathhold exams.

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Section: Resultssupporting

confidence: 87%

mentioning

confidence: 99%

Single breathhold cardiac CINE imaging with multi‐echo three‐dimensional hybrid radial SSFP acquisition

Liu

Wieben

Jung

et al. 2010

Magnetic Resonance Imaging

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“…Furthermore, the partition encoding direction of the 3D spiral dynamic scan can be accelerated with combinations of partial Fourier acceleration and through-time non-Cartesian GRAPPA [38,39] to shorten the breathhold, increase partition encoding resolution or expand the volumetric coverage. In the end, conservative scan and reconstruction parameters were selected for both methods at the expense of scan efficiency, where multiple slices with R = 2 [12], one slice with R = 1 [14,22] and one slice with R = 2 (as used in this study) per breathhold all yield high quality images against which ventricular functional parameters and image quality of a test method can be compared.…”

Section: Discussionmentioning

confidence: 99%

“…The breathhold for the dynamic scan for 3D k-t BLAST was reduced to an average of 15 s (plus an additional breathhold of 7-14 s for training data) by increasing acceleration to R = 6 and encoding data with in-plane resolution near 3 × 3 mm 2 followed by spatial interpolation [12]. Lower blood-myocardium contrast from reduced in-flow enhancement for 3D cine cardiac imaging [13] was improved for 3D k-t BLAST with the use of a contrast agent [14]; this study acquired dynamic data with a resolution of 2.4 × 2.4 × 10-12 mm 3 and then interpolated to 1.2 × 1.2 × 5-6 mm 3 . However, Bland-Altman analysis of systolic LV functional parameters still showed significant differences with a 2D cine standard.…”

Section: Introductionmentioning

confidence: 99%

Quantification of left ventricular functional parameter values using 3D spiral bSSFP and through-time Non-Cartesian GRAPPA

Barkauskas

Rajiah

Ashwath

et al. 2014

Journal of Cardiovascular Magnetic Resonance

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BackgroundThe standard clinical acquisition for left ventricular functional parameter analysis with cardiovascular magnetic resonance (CMR) uses a multi-breathhold multi-slice segmented balanced SSFP sequence. Performing multiple long breathholds in quick succession for ventricular coverage in the short-axis orientation can lead to fatigue and is challenging in patients with severe cardiac or respiratory disorders. This study combines the encoding efficiency of a six-fold undersampled 3D stack of spirals balanced SSFP sequence with 3D through-time spiral GRAPPA parallel imaging reconstruction. This 3D spiral method requires only one breathhold to collect the dynamic data.MethodsTen healthy volunteers were recruited for imaging at 3 T. The 3D spiral technique was compared against 2D imaging in terms of systolic left ventricular functional parameter values (Bland-Altman plots), total scan time (Welch’s t-test) and qualitative image rating scores (Wilcoxon signed-rank test).ResultsSystolic left ventricular functional values were not significantly different (i.e. 3D-2D) between the methods. The 95% confidence interval for ejection fraction was −0.1 ± 1.6% (mean ± 1.96*SD). The total scan time for the 3D spiral technique was 48 s, which included one breathhold with an average duration of 14 s for the dynamic scan, plus 34 s to collect the calibration data under free-breathing conditions. The 2D method required an average of 5min40s for the same coverage of the left ventricle. The difference between 3D and 2D image rating scores was significantly different from zero (Wilcoxon signed-rank test, p < 0.05); however, the scores were at least 3 (i.e. average) or higher for 3D spiral imaging.ConclusionThe 3D through-time spiral GRAPPA method demonstrated equivalent systolic left ventricular functional parameter values, required significantly less total scan time and yielded acceptable image quality with respect to the 2D segmented multi-breathhold standard in this study. Moreover, the 3D spiral technique used just one breathhold for dynamic imaging, which is anticipated to reduce patient fatigue as part of the complete cardiac examination in future studies that include patients.Electronic supplementary materialThe online version of this article (doi:10.1186/s12968-014-0065-1) contains supplementary material, which is available to authorized users.

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“…Hence, improved CS methods for maintaining both reasonable spatial and temporal quality of dynamic MR data at higher reduction factors are very desirable. Several extensions and improvements of k‐t‐BLAST/k‐t SENSE and CS techniques have been recently proposed (20–28).…”

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confidence: 99%

k‐t group sparse: A method for accelerating dynamic MRI

Usman

Prieto

Schaeffter

et al. 2011

Magnetic Resonance in Med

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Compressed sensing (CS) is a data-reduction technique that has been applied to speed up the acquisition in MRI. However, the use of this technique in dynamic MR applications has been limited in terms of the maximum achievable reduction factor. In general, noise-like artefacts and bad temporal fidelity are visible in standard CS MRI reconstructions when high reduction factors are used. To increase the maximum achievable reduction factor, additional or prior information can be incorporated in the CS reconstruction. Here, a novel CS reconstruction method is proposed that exploits the structure within the sparse representation of a signal by enforcing the support components to be in the form of groups. These groups act like a constraint in the reconstruction. The information about the support region can be easily obtained from training data in dynamic MRI acquisitions. The proposed approach was tested in two-dimensional cardiac cine MRI with both downsampled and undersampled data. Results show that higher acceleration factors (up to 9-fold), with improved spatial and temporal quality, can be obtained with the proposed approach in comparison to the standard CS reconstructions. Key words: compressed sensing; undersampling; group sparsity; l 1 minimization; dynamic MRI Dynamic MRI applications usually require high spatial and temporal resolution. The acquisition speed of MR images, however, is limited by physical (e.g., gradient strength and slew rate) and physiological (e.g., nerve stimulation) constraints (1). To address this issue, several reconstruction techniques have been proposed that can reconstruct MR images of significant quality from reduced data acquisitions. Following Tsao et al.'s classification (2), these techniques can be classified into those which exploit correlations in the k-space (3-8), in time domain (9-13) or in both k-space and time domains (2,14,15).Recently, a new data reduction technique titled ''compressed sensing'' (CS) (16,17) has been proposed for application in MRI. According to the CS theory, perfect reconstruction of a signal is possible from sampling rates below the Shannon-Nyquist limit, provided the signal is sparse (in itself or in some transform domain) and the measurement samples are obtained with an incoherent basis. For dynamic MRI, Lustig et al. proposed a CS technique called ''k-t sparse'' (18) in which the undersampled data acquisition was done in the phase encodetime dimension (k-t space) by randomly skipping the phase encodes for each time frame. The sparsity was introduced by transforming the dynamic MR data using a wavelet transform and a Fourier transform along spatial and temporal directions, respectively. Alternatively, Gamper et al. (19) showed that a Fourier transform along the temporal dimension was sufficient to achieve sparsity in x-f space, where x is spatial position and f is temporal frequency. For low reduction factors (up to 3-fold), Gamper demonstrated that CS reconstructions exhibit less error than k-t Broad-use Linear Acquisition Speedup Technique (BLAST...

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Rapid assessment of regional and global left ventricular function using three-dimensional k-t BLAST imaging

Cited by 8 publications

References 37 publications

Single breathhold cardiac CINE imaging with multi‐echo three‐dimensional hybrid radial SSFP acquisition

Single breathhold cardiac CINE imaging with multi‐echo three‐dimensional hybrid radial SSFP acquisition

Quantification of left ventricular functional parameter values using 3D spiral bSSFP and through-time Non-Cartesian GRAPPA

k‐t group sparse: A method for accelerating dynamic MRI

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