Rare benign tumours of the nipple

Abstract

Histological examination of the lesion can be the only definite answer in these cases.

Reflectance Confocal Microscopy for Diagnosis of Mammary Paget’s Disease

“…Pigmented mammary Paget's disease (PMPD) corresponds to an even less common variant, frequently simulating other pigmented lesions of the nipple, including melanoma (3)(4)(5). According to the epidermotropic theory, Paget cells (PCs) originate from cancer cells that migrate via the lactiferous ducts along the basal membrane, to invade the epidermis of the nipple and areola (6,7). Considering its intra-epidermal spreading, PCs are therefore potentially demonstrable using non-invasive diagnostic techniques with near-cellular resolution, such as reflectance confocal microscopy (RCM) (8).…”

Congenital Milium of the Nipple

“…Pearls in the areola are frequent, but involvement of the nipple seems to be rare. We found three published cases of milia in the nipple and only one was congenital (Table ) .…”

Unilateral nipple involvement in histoid leprosy

“…Nipples, the conical appendage of the human breast, can be associated with various dermatoses and benign tumors. The common causes of tumoral swelling of the nipple include neurofibroma, leiomyoma, florid papillomatosis of the nipple, syringomatous adenoma of the nipple, nevoid hyperkeratosis, fibroma, pseudolymphoma, and hemangioma . Histoid leprosy is a form of multibacillary leprosy, accounting for 1.8% of patients with leprosy in our clinic .…”

“…The common causes of tumoral swelling of the nipple include neurofibroma, leiomyoma, florid papillomatosis of the nipple, syringomatous adenoma of the nipple, nevoid hyperkeratosis, fibroma, pseudolymphoma, and hemangioma. 1 Histoid leprosy is a form of multibacillary leprosy, accounting for 1.8% of patients with leprosy in our clinic. 2 In the post-elimination era, cases of histoid leprosy are considered an important source of infection in the community.…”