2008
DOI: 10.1016/j.seppur.2008.04.005
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Reactive extraction of N-acetylneuraminic acid—Kinetic model and simulation of integrated product removal

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Cited by 22 publications
(12 citation statements)
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“…Finally, the use of COSMO-RS here evidences the fact that this tool has opened many doors for the selection of solvents and could open more for the screening of entrainers in combined operations for process intensification, including reactions followed by in situ extractions, [33][34][35][36] reactive extractions or reactive distillations, to name a few.…”
Section: Discussionmentioning
confidence: 72%
See 1 more Smart Citation
“…Finally, the use of COSMO-RS here evidences the fact that this tool has opened many doors for the selection of solvents and could open more for the screening of entrainers in combined operations for process intensification, including reactions followed by in situ extractions, [33][34][35][36] reactive extractions or reactive distillations, to name a few.…”
Section: Discussionmentioning
confidence: 72%
“…The use of such systems would have further advantages, such as thermodynamically shifting the reaction towards the products and concentrating it if the volume of the extracting solvent is kept low. 31,32 This approach has also been used to recover N-acetylneuraminic acid from the reacting medium in its enzymatic production from N-acetyl-D-mannosamine and sodium pyruvate 33,34 or for the separation of phenyl acetic acid by Alamine 336, a mixture of amines, from the aqueous enzymatic hydrolysis of penillicin G, 35,36 in both of cases to prevent enzymatic deactivation. The selection of solvents is a topic of concern in research and industrial practice as environmental policies lead to more and more restrictive regulations, such as REACH in the EU.…”
Section: Introductionmentioning
confidence: 99%
“…2) used in this study was manufactured at the glass shop of Zhejiang University, which was the same as shown elsewhere (Wasewar et al, 2002;Zimmermann et al, 2008). The cell was a glass cylinder of inside diameter 10 cm and height 11.5 cm, which was divided into two halves by an acrylic circular disc with a circular whole in the middle and a ring gasket.…”
Section: Determination Of Extraction Kineticsmentioning
confidence: 99%
“…The modified Lewis cell used in this study was the same as shown elsewhere (32,38). The cell was a glass cylinder of the inside diameter 6.4 cm and height 7.5 cm which was divided into two halves by an acrylic circular disc with a circular hole in the middle.…”
Section: Extraction Kineticsmentioning
confidence: 99%