Reactor design for the ABE fermentation using cells of Clostridium acetobutylicum immobilized by adsorption onto bonechar

Qureshi, N.; Maddox, I. S.

doi:10.1007/bf00369330

Cited by 62 publications

(34 citation statements)

References 9 publications

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“…PBRs suffer from excessive cell growth followed by blockage but the reaction rates are much higher as compared to batch reactors. 73 In the past, various materials such as bonechar, 83 coke, 84 beechwood shavings, 85 chitosan, carrageenan and sodium alginate matrices have been used as the support materials. 86 Recently, more immobilization materials were studied for PBR continuous reactors as listed in Table 3.…”

Section: Packed Bed Reactorsmentioning

confidence: 99%

Biobutanol: the outlook of an academic and industrialist

et al. 2013

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The gradual shift of transportation fuels from oil based fuels to the alternative fuel resources and worldwide demand for energy has been the impetus for research to produce alcohol biofuels from renewable resources. Current bioethanol and biodiesel can, however, not cover an increasing demand for biofuels. Hence, there is an extensive need for advanced biofuels with superior fuel properties. The present review is focused on the developments of biobutanol, which is regarded to be superior to bioethanol in terms of energy density and hygroscopicity. Although acetone-butanolethanol (ABE) fermentation is one of the oldest large-scale fermentation processes, butanol yield by anaerobic fermentation remains sub-optimal. For sustainable industrial scale butanol production, a number of obstacles need to be addressed including choice of feedstock, low product yield, product toxicity to production strain, multiple end-products and downstream processing of alcohol mixtures.Metabolic engineering provides a means for fermentation improvements. Different strategies are employed in the metabolic engineering of Clostridia that aim to enhance the solvent production, improve selectivity for butanol production, and increase the tolerance of Clostridia to solvents. The introduction and expression of a non-clostridial butanol producing pathway in E. coli is most promising strategy for butanol biosynthesis. Several rigorous kinetic and physiological models for fermentation have been formulated, which form useful tool for optimization of the process. Due to the lower butanol titers in the fermentation broth, simultaneous fermentation and product removal techniques have been developed to improve production economics. With the use of new strains, inexpensive substrates, and superior reactor designs, economic ABE fermentation may further attract an attention of researchers all over the world. The present review is attempting to provide an overall outlook on discoveries and strategies that are being developed for commercial n-butanol production.

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Section: Packed Bed Reactorsmentioning

confidence: 99%

Biobutanol: the outlook of an academic and industrialist

et al. 2013

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“…Single species biofilm are used to produce industrially important chemicals [22,23]. Such biofilms can exist in some situations and are important industrially, although in nature they are not the norm.…”

Section: Biofilm Formationmentioning

confidence: 99%

Biofilm reactors for industrial bioconversion processes: employing potential of enhanced reaction rates

et al. 2005

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This article describes the use of biofilm reactors for the production of various chemicals by fermentation and wastewater treatment. Biofilm formation is a natural process where microbial cells attach to the support (adsorbent) or form flocs/aggregates (also called granules) without use of chemicals and form thick layers of cells known as "biofilms." As a result of biofilm formation, cell densities in the reactor increase and cell concentrations as high as 74 gL -1 can be achieved. The reactor configurations can be as simple as a batch reactor, continuous stirred tank reactor (CSTR), packed bed reactor (PBR), fluidized bed reactor (FBR), airlift reactor (ALR), upflow anaerobic sludge blanket (UASB) reactor, or any other suitable configuration. In UASB granular biofilm particles are used. This article demonstrates that reactor productivities in these reactors have been superior to any other reactor types. This article describes production of ethanol, butanol, lactic acid, acetic acid/vinegar, succinic acid, and fumaric acid in addition to wastewater treatment in the biofilm reactors. As the title suggests, biofilm reactors have high potential to be employed in biotechnology/bioconversion industry for viable economic reasons. In this article, various reactor types have been compared for the above bioconversion processes.

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“…A fluidized bed reactor was the most stable of the systems investigated, and a productivity of 4.8 kg m was maintained for 2000 h of operation. The results demonstrate that this type of reactor may have a useful future role in the ABE fermentation [97]. Schoutens determined the optimal conditions necessary for the continuous BuOH production from whey permeate with C. beyerinckii LMD 27.6 immobilized in calcium alginate beads.…”

Section: Characteristics Of the Processmentioning

confidence: 95%