Real time device for biosensing: design of a bacteriophage model using love acoustic waves

Tamarin, Ollivier; Comeau, Sylvie; Déjous, Corinne; Moynet, Daniel; Rebière, Dominique; Bezian, J.; Pistré, Jacques

doi:10.1016/s0956-5663(03)00022-8

Cited by 78 publications

(35 citation statements)

References 12 publications

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“…[103][104][105][106][107][108][109][110][111][112][113] Among these methods, optical and electrochemical methods are the most frequently utilized due to their selectivity and sensitivity. Other than the above major methods, approaches such as nuclear magnetic resonance (NMR) spectroscopy, [114][115][116][117][118] magnetoresistive, 119 and acoustical 120,121 are also coupled to microfluidics for sensing application.…”

Section: Detection Methodsmentioning

confidence: 99%

Microfluidic sensing: state of the art fabrication and detection techniques

2011

J. Biomed. Opt.

176

141

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Section: Detection Methodsmentioning

confidence: 99%

Microfluidic sensing: state of the art fabrication and detection techniques

2011

J. Biomed. Opt.

176

141

View full text Add to dashboard Cite

“…In addition, the wave guide layer in the Love mode biosensor could, in principle, also protect and insulate the IDT from the liquid media which might otherwise be detrimental to the electrode. Therefore, they are frequently utilized to perform bio-sensing in liquid conditions (Lindner, 2008;Jacoby & Vellekoop, 1997;Bisoffi et al, 2008;Andrä et al, 2008;Moll et al, 2007Moll et al, , 2008Branch & Brozik, 2004;Tamarin et al, 2003;Howe & Harding, 2000), arising as the most promising SGAW device for this purpose due to its high mass sensitivity and electrode isolation characteristics from liquid media (Rocha-Gaso et al, 2009;Francis et al, 2005). The mass sensitivity of LW sensors can be evaluated by different techniques based on incremental modifications of the surface density on the sensing area of the device (Francis et al, 2004).…”

Section: Surface Generated Acoustic Wave Devices (Sgaw)mentioning

confidence: 99%

QCM Technology in Biosensors

Montagut¹,

Narbon²,

Jiménez³

et al. 2011

Biosensors - Emerging Materials and Applications

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“…Guard electrodes were included in the design shown in Fig.20c to suppress electric field edge effects. 0.125λ b 3 0.125λ b 4 0.250λ The EWC-SPUDT design in Fig. 20a produced a sinc(x) function type response with a phase linearity of 2° P-P (Fig 21a).…”

Section: Interdigital Transducer Designs and S21 Responsementioning

confidence: 99%

“…The transduction mechanism for Love wave sensors is based on propagating waves with a shearhorizontal polarization (SH) along the propagation direction. The SH polarization minimizes attenuation of the surface acoustic wave (SAW) into viscous media permitting detection in fluids [1][2][3][4].…”

Section: Introductionmentioning

confidence: 99%

Shear horizontal surface acoustic wave microsensor for Class A viral and bacterial detection.

Branch¹,

Huber²,

Brozik³

et al. 2008

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The rapid autonomous detection of pathogenic microorganisms and bioagents by field deployable platforms is critical to human health and safety. To achieve a high level of sensitivity for fluidic detection applications, we have developed a 330 MHz Love wave acoustic biosensor on 36° YX Lithium Tantalate (LTO). Each die has four delay-line detection channels, permitting simultaneous measurement of multiple analytes or for parallel detection of single analyte containing samples. Crucial to our biosensor was the development of a transducer that excites the shear horizontal (SH) mode, through optimization of the transducer, minimizing propagation losses and reducing undesirable modes. Detection was achieved by comparing the reference phase of an input signal to the phase shift from the biosensor using an integrated electronic multi-readout system connected to a laptop computer or PDA. The Love wave acoustic arrays were centered at 330 MHz, shifting to 325-328 MHz after application of the silicon dioxide waveguides. The insertion loss was −6 dB with an out-of-band rejection of 35 dB. The amplitude and phase ripple were 2.5 dB p-p and 2-3° p-p, respectively. Time-domain gating confirmed propagation of the SH mode while showing suppression of the triple transit. Antigen capture and mass detection experiments demonstrate 4 a sensitivity of 7.19 ± 0.74 ° mm 2 / ng with a detection limit of 6.7 ± 0.40 pg / mm 2 for each channel.5 CONTENTS

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Real time device for biosensing: design of a bacteriophage model using love acoustic waves

Cited by 78 publications

References 12 publications

Microfluidic sensing: state of the art fabrication and detection techniques

Microfluidic sensing: state of the art fabrication and detection techniques

QCM Technology in Biosensors

Shear horizontal surface acoustic wave microsensor for Class A viral and bacterial detection.

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