“…Bulk nanobubbles possess distinct features such as extraordinary longevity, high surface to volume ratio , high mass transfer coefficient and Laplace pressure, ability to generate reactive oxygen species. Owing to such peculiar properties, nanobubbles have wide range of applications in the field of wastewater treatment [1] , [2] , medical application [3] , food processing [4] , environmental sectors [5] , bio-engineering sectors [6] , flotation [7] , therapeutic delivery [8] . Despite such overwhelming applications, the fundamental understanding of nanobubble generation [9] and a unique characterization technique to distinguish nanobubbles from the particle and nanodroplet [10] are still under infancy.…”