2023
DOI: 10.1016/j.jconrel.2023.05.009
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Recent advances in biomimetic nanodelivery systems: New brain-targeting strategies

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Cited by 41 publications
(7 citation statements)
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“…As the most selective physiological barrier in the human body ( Liao et al, 2023 ), the BBB protects the CNS from potentially harmful substances, although this also presents considerable challenges for the treatment of CNS disease ( Nilles et al, 2022 ). Many drugs cannot penetrate the BBB, resulting in an insufficient effective concentration of drugs ( Yang et al, 2019 ).…”
Section: Protective Effects Of Salvianic Acid a Against Cerebral I/r ...mentioning
confidence: 99%
“…As the most selective physiological barrier in the human body ( Liao et al, 2023 ), the BBB protects the CNS from potentially harmful substances, although this also presents considerable challenges for the treatment of CNS disease ( Nilles et al, 2022 ). Many drugs cannot penetrate the BBB, resulting in an insufficient effective concentration of drugs ( Yang et al, 2019 ).…”
Section: Protective Effects Of Salvianic Acid a Against Cerebral I/r ...mentioning
confidence: 99%
“…The application of CMNVs in the treatment of IS has recently been reviewed. Li et al and Liao et al provided overviews of the applications of CMNVs in various brain diseases, including gliomas, IS, Parkinson’s disease, and Alzheimer’s disease [ 29 ]. Liu et al specifically focused on the progress of CMNVs in IS treatment.…”
Section: Introductionmentioning
confidence: 99%
“… 10 The need for new treatments for neurodegenerative diseases and the limitations imposed by the BBB are driving the adoption of nanotechnology. 11 Exosomes (Exos) are extracellular nanovesicles that participate in various physiological processes and exert pathological activities, including intracellular signalling and intercellular transport of protein and RNA. 12 Emerging clinicopathological and experimental studies have suggested the crucial role of Exos in intercellular communication and in the transportation of materials in the CNS and their excellent biocompatibility for drug delivery.…”
Section: Introductionmentioning
confidence: 99%