Abstract. In this paper, physical and numerical simulations were applied to investigate the polymer degradation performance and its effect on polymer enhanced oil recovery (EOR) efficiency in homogeneous reservoirs. Physical experiments were conducted to determine basic physicochemical properties of the polymer, including viscosity, rheology, and degradation. A new mathematical model was proposed, and an in-house simulator was designed to further explore polymer degradation. The results of the physical experiments illustrated that polymer could increase polymer solution viscosity significantly, and the relationship between polymer solution viscosity and polymer concentration exhibited a clear power law relationship. However, the viscosity of a polymer solution with the same polymer concentration decreased with an increase in the shear rate, showing shear thinning performance. Moreover, the viscosity decreased with an increase in time, which was caused by polymer degradation. The validation of the designed simulator was improved when compared to the simulation results using ECLIPSE V2013.1 software. The difference between 0 and 0.1 day -1 in the polymer degradation rate showed a decrease of 6% in oil recovery after 2,000 days, according to simulation results, which demonstrated that polymer degradation had an adverse effect on polymer flooding efficiency.