Recent Advances in Translational Work on Implantable Sensors

Abstract

This review evaluates example technologies from the point-of-view of likely translation into human use, including regulatory clearance, insertion into common medical practice and reimbursability. The intent is to highlight recent innovations in implantable sensors with a focus on the translational process itself in a holistic fashion. As well as looking at success stories, this review will also examine several seemingly promising technologies that have failed for reasons having nothing to do with the operational aspects of the sensors and systems involved. Innovation must be viewed as a multifaceted process, all segments of which must be fully addressed to achieve success. No party to the process can work in isolation and expect to achieve the end goal of providing new advances to patients. This review will have succeeded if it provides the reader with a better appreciation of the complex environment in which implantable sensor discoveries that seek to be translated into human medicine must navigate.Index Terms-Implantable sensors, sensor systems, in vivo medical devices.

Co-Designing Personal Health? Multidisciplinary Benefits and Challenges in Informing Diabetes Self-Care Technologies

“…We identified translational work challenges between HCI and AI academics and participants living with type 1 diabetes. The terms translational research and translational work are being used, in particular, in the biomedical domain to refer to the translation of scientific findings into medical practice [6,13]. Norman highlights the need for translational developers who can mediate between academia and industry [58].…”

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“…Moreover, a wide range of implants are now being envisioned for sensing, in-vivo drug delivery and other applications [2], [4]. Typically, these implants are powered by batteries that either need to be replaced periodically or need to be charged by wireless means [3].…”

23.2 A 1.1nW energy harvesting system with 544pW quiescent power for next-generation implants

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