Recent advances on small-molecule fluorophores with emission beyond 1000 nm for better molecular imaging in vivo

Structural and process controls of AIEgens for NIR-II theranostics

“…2a). [14][15][16][17][18][19][20][21][22][23][24][25][26][27][28] However, the uorescence efficiency (F) decreases remarkably with wavelength (l), especially in low energy bandgap NIR-II materials, as intramolecular motions around the single or double bond result in dominant non-radiative relaxation dynamics (Fig. 2b).…”

Rational design of a multifunctional molecular dye for dual-modal NIR-II/photoacoustic imaging and photothermal therapy

“…[39][40][41][42][43][44] Beneting from their excellent photo-stability and uorescence features, diverse biological practices such as vascular/lymphatic and tumor uorescence imaging with a high signal to background ratio (S/B) as well as precise uorescence image-guided surgery indeed bring good news for biomedical applications in the NIR-II channel. [45][46][47][48][49][50][51][52][53][54][55][56][57][58][59][60] Despite these excellent uorescence imaging results, the potential utilization of these molecular dyes for multimodal imaging or even cancer theranostics is rarely explored.…”

Rationally Designed Furocarbazoles as Multifunctional Aggregation Induced Emissive Luminogens for the Sensing of Trinitrophenol (TNP) and Cell Imaging

“…Fluorescence imaging of biological cells and tissues and real‐time monitoring of biosamples reveal information of biological structures, providing accurate diagnostic tools and treatment of disease . Luminogens or AIEgens which can lit up under the influence of bio‐environment are regarded as prospective candidates to be used as fluorescent bioprobes.…”