Recent progress and prospects of alkaline phosphatase biosensor based on fluorescence strategy

Han, Yong-Jun; Chen, Jia; Li, Zhan; Chen, Hongli; Qiu, Hongdeng

doi:10.1016/j.bios.2019.111811

Cited by 129 publications

(57 citation statements)

References 165 publications

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“…Optical detection utilizes the properties of light, such as absorbance, fluorescence, and the emission mode of the sample when excited. Among optical detection methods, the fluorescence method is commonly used because it is sensitive, cheap, fast, and easy to operate [189]. The key to designing a fluorescence biosensor is fluorescent dyes or the labeling of fluorophores.…”

Section: Optical Detectionmentioning

confidence: 99%

Public-Health-Driven Microfluidic Technologies: From Separation to Detection

Zhang

Wang

et al. 2021

Micromachines

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Separation and detection are ubiquitous in our daily life and they are two of the most important steps toward practical biomedical diagnostics and industrial applications. A deep understanding of working principles and examples of separation and detection enables a plethora of applications from blood test and air/water quality monitoring to food safety and biosecurity; none of which are irrelevant to public health. Microfluidics can separate and detect various particles/aerosols as well as cells/viruses in a cost-effective and easy-to-operate manner. There are a number of papers reviewing microfluidic separation and detection, but to the best of our knowledge, the two topics are normally reviewed separately. In fact, these two themes are closely related with each other from the perspectives of public health: understanding separation or sorting technique will lead to the development of new detection methods, thereby providing new paths to guide the separation routes. Therefore, the purpose of this review paper is two-fold: reporting the latest developments in the application of microfluidics for separation and outlining the emerging research in microfluidic detection. The dominating microfluidics-based passive separation methods and detection methods are discussed, along with the future perspectives and challenges being discussed. Our work inspires novel development of separation and detection methods for the benefits of public health.

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Section: Optical Detectionmentioning

confidence: 99%

Public-Health-Driven Microfluidic Technologies: From Separation to Detection

Zhang

Wang

et al. 2021

Micromachines

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“…Fluorescence biosensors are a type of biosensors that have been widely employed for POC diagnostics of infectious diseases due to their appealing advantages of high sensitivity, low cost, easily operation and rapid analysis [122] , [123] , [124] , [125] , [126] , [127] . Labeling of fluorophores, either fluorescent dyes or fluorescent nanomaterials, is always essential for the establishment of a fluorescence biosensor.…”

Section: Detection Methods For Poc Diagnostic Applicationsmentioning

confidence: 99%

Point-of-care diagnostics for infectious diseases: From methods to devices

et al. 2021

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“…Recently, the electrochemical based methods overcome the above disadvantages, and have the advantages of low manufacturing cost, high sensitivity and high selectivity [8,9]. There are many techniques for the electrochemical, such as metal ion-induced optical [10], fluorescence detection [11]. They are considered to be better alternatives for urea determination.…”

Section: Introductionmentioning

confidence: 99%