Recovery and concentration of basic amino acids by electrodialysis with bipolar membranes

Abstract

Recovery and concentration of basic amino acids by electrodialysis with bipolar membranes are studied. The utilization of bipolar membranes leads to an increase of amino acids fluxes through monopolar membranes. No-flow concentration compartments give the possibility to concentrate amino acid solutions. Concentration factors have been obtained in a wide range of current density for basic amino acids with various side chains (lysine, arginine, histidine). The feed solution concentration influence on concentration factor is discussed. The correlation between the hydration of monopolar membranes in amino acids forms and concentration efficiency during the electrodialysis with bipolar membranes is found.

Bipolar Membrane Electrodialysis for Direct Conversion of L-Ornithine Monohydrochloride to L-Ornithine

“…Cations in the dilute solution migrate through CEM with a direction from the anode to the cathode under the driving force of direct current, while anions in the dilute solution migrate through AEM with the opposite direction [10]. Currently, ED has been used widely in the fields of salt concentration [11], feed desalination [12,13], ion metathesis reaction [14,15], ion substitution [16,17], acid and base production [18][19][20][21][22], etc. For instance, as for the separation of basic amino acid, Kattan Readi et al [23] reported that 1,5 pentanediamine (PDA) can be separated from L-arginine (Arg) by ED at a pH of 10 (PDA +1.5 /Arg ± ) with a high recovery ratio of 63%.…”

“…Simultaneously, Cl − ions in the feed compartment migrate through AEM to the acid compartment, thus the L-lysine was produced. Eliseeva et al [22] reported the recovery and concentration of basic amino acids (lysine, arginine and histidine) by BMED (the BP-C configuration), in which the positively charged basic amino acids in the acid compartment migrate through CEM to the base compartment, and combine with OH − ions generated by BPM to produce the basic amino acids. Meanwhile, the concentration of basic amino acids can be increased 35-50 times.…”

Electro-membrane processes for organic acid recovery

“…ED was able to recover 63-65% amino acid 133 and tartaric acid, 152 85% of butyric acid, and more than 90% of glyceric acid 140 and lactic acid. 3,16,143 Meanwhile, EDBM has been used for the recovery of acetic acid, 132 amino acid, 134,135 citric acid, 137,138 fumaric acid, 139 lactic acid, 142 malic acid, 145 propionic acid, 116 salicylic acid, 121,146 and succinic acid. 149 Most of the studies on EDBM mainly focused on the current efficiency, where the results showed that the current efficiency for organic acid recovery was affected by the EDBM stack conguration and feed characteristics.…”

Bipolar nanofiltration membranes based on plasma modified microfilters

“…This technique called EDBM (electrodialysis with BPM) has found a large number of new applications in chemical industry, in food and drug industry as well as in waste water treatment or production of high quality water. Among EDBM processes described so far one can find: production of specific organic compounds, mainly acids, removal of boron from aqueous solution, regeneration of CO 2 or other chemicals, recovery of amino acids, water electrolysis for H 2 production, inactivation of the enzymes in juice manufacturing, and others.…”