2018
DOI: 10.1177/0885328218759385
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Red light accelerates the formation of a human dermal equivalent

Abstract: Development of biomaterials' substitutes and/or equivalents to mimic normal tissue is a current challenge in tissue engineering. Thus, three-dimensional cell culture using type I collagen as a polymeric matrix cell support designed to promote cell proliferation and differentiation was employed to create a dermal equivalent in vitro, as well to evaluate the photobiomodulation using red light. Polymeric matrix cell support was prepared from porcine serous collagen (1.1%) hydrolyzed for 96 h. The biomaterial exhi… Show more

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Cited by 5 publications
(3 citation statements)
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“…Non-ionising electromagnetic radiation (EMR) in the visible light spectrum has been used as a therapeutic modality to improve wound and soft tissue healing, reduce the appearance of aging, increase the rate of hair growth, reduce pain and inflammation, and has potential as an alternative cancer therapy [6][7][8][9][10][11] . More recently, light has demonstrated utility during in vitro cell and tissue culture, acting as an antioxidant substitute post-thawing of human stem cells and accelerating the formation of a dermal equivalent for human skin modelling 12,13 . Previously referred to as low-level laser therapy (LLLT), the use of light in biology is now more accurately referred to as photobiomodulation (PBM).…”
mentioning
confidence: 99%
“…Non-ionising electromagnetic radiation (EMR) in the visible light spectrum has been used as a therapeutic modality to improve wound and soft tissue healing, reduce the appearance of aging, increase the rate of hair growth, reduce pain and inflammation, and has potential as an alternative cancer therapy [6][7][8][9][10][11] . More recently, light has demonstrated utility during in vitro cell and tissue culture, acting as an antioxidant substitute post-thawing of human stem cells and accelerating the formation of a dermal equivalent for human skin modelling 12,13 . Previously referred to as low-level laser therapy (LLLT), the use of light in biology is now more accurately referred to as photobiomodulation (PBM).…”
mentioning
confidence: 99%
“…The amount of glass transition temperature was obtained by the curve inflection. In this work, T g was expressed as the midpoint of the step 45,46 …”
Section: Methodsmentioning
confidence: 99%
“… 101 It seems that PBM activates cell division in sufficiently soft scaffold systems, such as decellularized dermal matrices and hydrogels. 160 162 …”
Section: Pbm For Tissue Engineering and Regenerative Medicinementioning
confidence: 99%