Redox‐Responsive Macroscopic Gel Assembly Based on Discrete Dual Interactions

Abstract

The macroscopic self-assembly of polymeric hydrogels modified with β-cyclodextrin (βCD gel), ferrocene (Fc gel), and styrenesulfonic acid sodium salt (SSNa gel) was investigated. Under reductive conditions, the Fc gel selectively adhered to the βCD gel through a host-guest interaction. On the other hand, the oxidized ferrocenium (Fc(+)) gel selectively adhered to the SSNa gel through an ionic interaction under oxidative conditions. The adhesion strength was estimated by a tensile test. We finally succeeded in forming an ABC-type macroscopic assembly of all three gels through two discrete noncovalent interactions.

Redox-responsive polymeric membranes via supermolecular host–guest interactions

“…It was known that Fc and β-CD could form inclusion complex due to the interaction between Fc and β-CD [36,48,49]. To figure out the interaction between PES-PEG-Fc and PES-PEG-β-CD, 2D NMR (NOESY) spectra test was performed to evidence the formation and dissociation of the inclusion complex between the Fc moieties on PES-PEG-Fc and the β-CD moieties on PES-PEG-β-CD.…”

“…The host-guest complex between Fc and β-CD has attracted enormous attention due to its reversible redox-responsive property and good stability in water system. Fc in reduced state acts as a hydrophobic guest, which could insert into hydrophobic cavity of CD and further form 1:1 complex with β-CD due to the strong hydrophobic interaction between Fc and β-CD; whereas in the oxidized state, the hydrophobic binding of positively charged Fc ions (Fc þ ) to CDs turns weak, which induces the dissociation of the complexes between Fc and β-CD [2,[35][36][37][38].…”

Supramolecular Polymeric Materials Containing Cyclodextrins

“…Two kinds of non-covalent interactions can be used to form a sequenceregulated assembly. 31) 2.3.6. Potential Applications The process of macroscopic self-assembly and adhesion through CD-guest interaction can be used for various applications ranging from adhesion between dissimilar materials 32) and semi-dry materials, 33) programmable self-assembly toward two dimensional (2D) and 3D scaffolds.…”

Macroscopic Self‐Assembly Based on Complementary Interactions between Nucleobase Pairs

“…[29] More recently, there have been some reports on macroscopic adhesion systems based on various noncovalent interactions, as represented by dynamic covalent bonds, [30,31] ion-ion interactions, [32,33] hydrogen bonds, [34] and so on. [35] Most recently, a DNA-based gel assembly system was developed by using a DNA polymerase-mediated rolling circle amplification (RCA) method on the surface of a gel; [36] alternatively, we have been studying gel assembly by using oligonucleotides.…”