Reduced body protein in children with spastic quadriplegic cerebral palsy

Arrowsmith, Fiona; Allen, Jim; Gaskin, Kevin; Gruca, Margaret; Clarke, Samantha L.; Briody, Julie; Howman‐Giles, Robert; Somerville, Helen; O’Loughlin, Edward

doi:10.1093/ajcn.83.3.613

Cited by 36 publications

(31 citation statements)

References 31 publications

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“…, 23 , 24 The present study, when assessing the fat-free mass by AMC, found different results from those reported in the literature, as most patients had a nutritional classification of normal weight, evidencing that the lean body mass of the assessed patients was still preserved.…”

Section: Discussioncontrasting

confidence: 99%

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Avaliação antropométrica de pacientes pediátricos com encefalopatia crônica não progressiva segundo diferentes métodos de classificação

Teixeira

Gomes

2014

Revista Paulista de Pediatria

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Objective:To perform anthropometric assessment of patients with quadriplegic, chronic non-progressive encephalopathy, comparing two distinct references of nutritional classification and to compare the estimated height to the length measured by stadiometer. Method:Cross-sectional study including 0-3-year children with quadriplegic chronic non-progressive encephalopathy in secondary public hospital. Length, weight, arm circumference, triceps skinfold and knee height were measured. The arm muscle circumference and estimated height were calculated. The following relations were evaluated: weight-for-age, length-for-age and weight-for-length, using as reference the charts of the World Health Organization (WHO) and those proposed by Krick et al. Results:Fourteen children with a mean age of 21 months were evaluated. Assessment of anthropometric indicators showed significant difference between the two classification methods to assess nutritional indicators length/age (p=0.014), weight/age (p=0.014) and weight/length (p=0.001). There was significant correlation between measured length and estimated height (r=0.796, p=0.001). Evaluation of arm circumference and triceps skinfold showed that most patients presented some degree of malnutrition. According to arm muscle circumference, most were eutrophic. Conclusions:Specific curves for children with chronic non-progressive encephalopathy appear to underestimate malnutrition when one takes into account indicators involving weight. Curves developed for healthy children can be a good option for clinical practice and weight-for-length indicator and body composition measurements should be considered as complementary tools.

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Section: Discussioncontrasting

confidence: 99%

“…, 23 , 24 O presente estudo, ao avaliar a massa livre de gordura por meio da circunferência muscular do braço, encontrou resultados diferentes dos relatados pela literatura, já que a maioria apresentou classificação nutricional de eutrofia, mostrando que a massa magra dos pacientes avaliados ainda está preservada.…”

Section: Discussionunclassified

Avaliação antropométrica de pacientes pediátricos com encefalopatia crônica não progressiva segundo diferentes métodos de classificação

Teixeira

Gomes

2014

Revista Paulista de Pediatria

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“…Moreover, children and adults with CP have significantly diminished lean body mass [29] and greater intermuscular adipose tissue [30], which collectively highlights the implications of skeletal muscle deterioration. Thus, even normal BMIs in this population may disguise excess body fat (i.e., “obesity misclassification” [31]), and risk for cardiovascular and metabolic dysregulation.…”

Section: Discussionmentioning

confidence: 99%

Abdominal obesity is an independent predictor of serum 25-hydroxyvitamin D deficiency in adults with cerebral palsy

et al. 2014

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BackgroundIndividuals with cerebral palsy (CP) are at risk for nutritional insufficiency. The purpose of the study was to examine the vitamin D status of adults with CP, and to evaluate the association between vitamin D and functional level, age, race, and anthropometric indicators of adiposity.MethodsSerum vitamin D levels, BMI, waist circumference (WC), and functional level (measured by Gross Motor Function Classification System (GMFCS)) were examined in 112 adults with CP. Vitamin D status was assessed by serum 25-hydroxyvitamin D level (25(OH)D). The influence of motor impairment and adiposity on 25(OH)D were assessed using general linear modeling and logistic regression, with age, sex, race, and season as covariates.ResultsMean vitamin D was 28.1 ± 16.0 ng/ml. Only 45% of subjects had optimal levels of 25(OH)D, 21% were insufficient and 34% were deficient. Overweight or obesity was prevalent (52%), as was abdominal obesity in men (23.5% at 102 cm cutoff) and women (31.1% at 88 cm cutoff). There was a robust association between the indicator of visceral adiposity (WC) and 25(OH)D level (p <0.001), even after controlling for age, sex, race, season, and GMFCS. According to sex-specific WC cutoffs, the odds of being deficient in vitamin D increase by a factor of 3.5 (95% CI 1.12-11.0) for abdominal obesity. GMFCS was not associated with 25(OH)D.ConclusionsAdults with CP are at risk for low vitamin D levels and overweight/obesity. Waist circumference is a strong independent predictor for low vitamin D levels.

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“…However, recent studies have shown that children with CP with a lower degree of involvement (hemiparetic and diparetic) and with better function have a higher rate of obesity compared to children with CP with a higher degree of involvement. Similarly, children with a low degree of involvement have a lower rate of neuromuscular disorder arising from spasticity and decreased motor control which affect functional activities in daily life compared to children with a moderate and high degree of involvement (5)(6)(7)(8). However, they have less energy consumption, limited participation in physical activities and sportive activities compatible with their age compared to their healthy peers (5,9).…”

Section: Introductionmentioning

confidence: 99%

Examination of the relation between body mass index, functional level and health-related quality of life in children with cerebral palsy

Şimşek¹,

Tuç²

2014

Turk Arch Ped

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Aim: The aim of this study was to examine the relation between body mass index (BMI) and functional level and health-related quality of life in children with cerebral palsy (CP). Material and Methods:Two hundred seventy-eight children with CP aged between 2 and 18 years were included in the study. The sociodemographic properties of the children were recorded. Their functional independence levels were assessed with WeeFIM and their health-related quality of life levels were assessed with the Child Health Questionnaire-Parent Form (PF-50). Approval was obtained from the ethics committee of Abant İzzet Baysal University Medical Faculty for this study (Number: 2008/100-77).Results: When classified by body mass index, 26.3% of the children had a normal body weight, 5.4% were overweight, 11.5% were obese and 56.8% had a low body weight. The rate of low body weight was higher in children with moderate and severe CP (52.7% and 53.8%, respectively), while the rate of obesity was higher in children with mild CP who could walk (7.1%). A significant difference was found in children with CP with a normal body weight, overweight children with CP, obese children with CP and children with CP with a low body weight in terms of the total WeeFIM score and the variables of quality of life including physical functionality and role/social limitations because of physical health (p<0.05). In the correlation analysis, a positive correlation was found between WeeFIM and BMI and the subdimensions of role/social limitations because of emotional or behavioral difficulties, pain and discomfort and self-esteem (p<0.05). Conclusions:Our results showed that BMI affected functional independence and health-related quality of life in children with CP and this was more prominent in children who had severe CP and low BMI values. More studies are needed in this area. (Türk Ped Arş 2014; 49: 130-7)

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Reduced body protein in children with spastic quadriplegic cerebral palsy

Abstract: Body protein in children with SQCP is significantly reduced for age and height. Skinfold anthropometry and DXA show wide variation in estimation of body protein compared with NAA in this group of children.

Cited by 36 publications

References 31 publications

Avaliação antropométrica de pacientes pediátricos com encefalopatia crônica não progressiva segundo diferentes métodos de classificação

Avaliação antropométrica de pacientes pediátricos com encefalopatia crônica não progressiva segundo diferentes métodos de classificação

Abdominal obesity is an independent predictor of serum 25-hydroxyvitamin D deficiency in adults with cerebral palsy

Examination of the relation between body mass index, functional level and health-related quality of life in children with cerebral palsy

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