Reduced graphene oxide-yttria nanocomposite modified electrode for enhancing the sensitivity of electrochemical genosensor

Employing Label‐free Electrochemical Biosensor Based on 3D‐Reduced Graphene Oxide and Polyaniline Nanofibers for Ultrasensitive Detection of Breast Cancer BRCA1 Biomarker

“…One of the main label-free strategies is to direct detection of the redox active nucleobase based on its electrochemical property (such as guanine oxidation), and different redox markers such as Ferrocene and Methylene blue (MB) are adopted. Hence, electrochemical DNA biosensors are widely employed as an appropriate technique for early cancer and mutation detection, owing to their outstanding features including label-free, low cost, portable, highly sensitive and selective performance, and simplicity of detection in biological fluids [22][23][24][25].…”

New Design of Active Material Based on YInWO4-G-SiO2for a Urea Sensor and High Performance for Nonenzymatic Electrical Sensitivity

“…Yttrium also shows a high surface-to-volume ratio, quick oxygen ion mobility, productive charge transferability, chemical inertness, sharp line emission bands, and biocompatibility. − , Besides, it is known to have a high quantum yield, amazing photostability, and a low dielectric constant ( k ). Thus, it might have a potential application toward the development of biosensors. − , Tungstate (WO 4 ) has attracted significant consideration due to its unprecedented physicochemical properties and reasonable applications as electrode material in different areas, e.g., photoanodes, supercapacitors, memory devices, and humidity sensors. − , Finally, SiO 2 materials have a large surface area (700 and 500 m 2 g –1 ), good biocompatibility, nontoxicity, high ionic conductivity, and good chemical and thermal stability, making them perfect for use as supports for adsorption, catalysis, chemical separations, biosensors, and so on. − , …”

“…Thus, it might have a potential application toward the development of biosensors. [28][29][30][31][32]70 Tungstate (WO 4 ) has attracted significant consideration due to its unprecedented physicochemical properties and reasonable applications as electrode material in different areas, e.g., photoanodes, supercapacitors, memory devices, and humidity sensors. [33][34][35][36][37][38]71 Finally, SiO 2 materials have a large surface area (700 and 500 m 2 g −1 ), good biocompatibility, nontoxicity, high ionic conductivity, and good chemical and thermal stability, making them perfect for use as supports for adsorption, catalysis, chemical separations, biosensors, and so on.…”

Biofunctionalized Nanostructured Yttria Modified Non-Invasive Impedometric Biosensor for Efficient Detection of Oral Cancer

“…Among these NMOs, the nano-sized yttrium oxide (Yattria, nY 2 O 3 ) exhibits high surface-to-volume ratio, fast oxygen ion mobility, efficient charge transfer ability, chemical inertness, sharp line emission bands, and biocompatibility [34,35,36]. In addition, it is known to have high quantum yield, excellent photo stability, and low dielectric constant (k), making it a potential candidate for application towards the development of biosensors [37,38,39,40,41]. The low dielectric constant (13) of yttrium oxide makes the thin film highly conductive [42].…”

“…Besides this, the oxygen moieties in Y 2 O 3 can facilitate functionalization and covalent immobilization of antibodies. Rasheed et al developed yttria-reduced graphene oxide nanocomposite based genosensor for detection of BRCA 1 (breast cancer) gene [40]. Efforts have also been made to use yttria–zirconia nanocomposite for the fabrication of sensors that can be used for detection of hydrogen, oxygen, and nitric oxide [41,43].…”